Expression
Positive expression of a PDG in a given cancer type was defined as its mRNA expression was reliably detected in at least 50% of tumor specimens (i.e., the 50th percentile of fragments per kilobase of transcript per million mapped reads [FPKM] value ≥1).
Summary of PDG mRNA expression levels (FPKM value) in each cancer type
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HGNC | Ensembl | No. Detectable | ACC | BLCA | BRCA | CESC | CHOL | COAD | DLBC | ESCA | GBM | HNSC | KICH | KIRC | KIRP | LAML | LGG | LIHC | LUAD | LUSC | MESO | OV | PAAD | PCPG | PRAD | READ | SARC | SKCM | STAD | TGCT | THCA | THYM | UCEC | UCS | UVM | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Symbol | Gene ID | Cancer Types | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th | 25th | 50th | 75th | 90th |
EGFR | ENSG00000146648 | 28 | 1.61 | 3.77 | 7.82 | 13.04 | 4.92 | 10.04 | 19.33 | 37.44 | 1.03 | 2.35 | 5.16 | 10.06 | 7.53 | 15.15 | 24.65 | 38.07 | 6.8 | 9.25 | 12.83 | 21.28 | 5.06 | 6.67 | 9.17 | 12.23 | 0.26 | 0.46 | 0.84 | 1.45 | 13.77 | 26.62 | 52.14 | 99.47 | 14.09 | 55.61 | 247.86 | 476.76 | 18.8 | 29.82 | 44.48 | 74.36 | 3.86 | 7.53 | 14.65 | 23.01 | 19.03 | 29.33 | 42.29 | 61.42 | 6.23 | 10.07 | 15.34 | 21.73 | 0 | 0.01 | 0.07 | 0.15 | 18.48 | 33.61 | 51.11 | 99.34 | 5 | 7.72 | 12.78 | 20.99 | 6.8 | 12.57 | 22.41 | 38.86 | 14.95 | 23.19 | 36 | 57.07 | 7.26 | 13.43 | 21.86 | 36.96 | 1.89 | 3.33 | 5.68 | 8 | 5.82 | 7.61 | 10.34 | 14.31 | 0.21 | 0.48 | 1.14 | 3.16 | 7.06 | 10.28 | 14.17 | 18.34 | 5.45 | 7.11 | 9.27 | 10.77 | 3.55 | 6.13 | 11.3 | 18.66 | 0.16 | 0.4 | 1.1 | 2.79 | 6.63 | 10.17 | 14.07 | 22.26 | 0.82 | 1.53 | 3.01 | 6.05 | 7.73 | 11.95 | 17.44 | 23.7 | 5.35 | 10.92 | 20.89 | 31.69 | 2.1 | 3.74 | 6.17 | 9.83 | 2.5 | 5.93 | 8.12 | 14.77 | 0.19 | 0.3 | 0.51 | 0.8 |
FLT3 | ENSG00000122025 | 1 | 0.01 | 0.03 | 0.08 | 0.17 | 0.02 | 0.06 | 0.16 | 0.34 | 0.22 | 0.63 | 2.05 | 4.99 | 0.04 | 0.1 | 0.21 | 0.39 | 0.05 | 0.11 | 0.46 | 0.97 | 0.03 | 0.08 | 0.17 | 0.27 | 0.15 | 0.31 | 0.72 | 1.28 | 0.04 | 0.08 | 0.18 | 0.3 | 0.03 | 0.07 | 0.13 | 0.26 | 0.05 | 0.12 | 0.27 | 0.51 | 0 | 0.01 | 0.04 | 0.1 | 0.19 | 0.35 | 0.61 | 1.09 | 0.07 | 0.19 | 0.48 | 1.56 | 42.86 | 76.74 | 113.97 | 152.58 | 0.07 | 0.13 | 0.23 | 0.43 | 0.02 | 0.06 | 0.14 | 0.27 | 0.12 | 0.25 | 0.43 | 0.68 | 0.06 | 0.15 | 0.28 | 0.5 | 0.22 | 0.51 | 1.28 | 2.93 | 0.02 | 0.06 | 0.12 | 0.21 | 0.16 | 0.56 | 1.23 | 2.14 | 0.02 | 0.03 | 0.07 | 0.14 | 0.06 | 0.12 | 0.22 | 0.38 | 0.04 | 0.08 | 0.14 | 0.26 | 0.03 | 0.09 | 0.23 | 0.66 | 0.04 | 0.1 | 0.26 | 0.54 | 0.06 | 0.14 | 0.27 | 0.5 | 0.19 | 0.3 | 0.51 | 0.68 | 0.02 | 0.07 | 0.16 | 0.37 | 0.5 | 0.8 | 1.26 | 2 | 0.02 | 0.06 | 0.13 | 0.25 | 0.02 | 0.04 | 0.1 | 0.26 | 0 | 0.01 | 0.03 | 0.07 |
CCNE1 | ENSG00000105173 | 31 | 8.64 | 15.05 | 24.1 | 39.49 | 7.31 | 12.17 | 21.96 | 33.06 | 1.26 | 2.16 | 4.61 | 12.71 | 8.14 | 11.24 | 14.92 | 19.69 | 2.69 | 3.93 | 5.38 | 8.1 | 4.72 | 6.93 | 9.74 | 13.12 | 10.49 | 13.22 | 16.68 | 24.64 | 4.13 | 6.17 | 9.38 | 16.14 | 2.27 | 3.33 | 5.29 | 7.82 | 4.12 | 6.16 | 8.77 | 12.19 | 1 | 1.23 | 1.79 | 2.12 | 0.61 | 0.81 | 1.26 | 1.82 | 0.84 | 1.21 | 1.87 | 3.14 | 4.41 | 7.32 | 10.55 | 13.6 | 1.29 | 1.73 | 2.4 | 3.3 | 0.67 | 1.36 | 3.38 | 7.69 | 1.84 | 3.24 | 6.73 | 12.78 | 4.82 | 7.21 | 12.04 | 18.26 | 1.32 | 2.29 | 3.26 | 5.23 | 10.07 | 17.4 | 30.49 | 49.68 | 2.05 | 2.8 | 3.75 | 5.89 | 1.37 | 2 | 3.01 | 4.54 | 0.64 | 0.85 | 1.18 | 1.59 | 4.71 | 7 | 10.67 | 14.99 | 2.98 | 6 | 12.67 | 21.8 | 3.69 | 5.42 | 7.75 | 11.46 | 3.02 | 5.26 | 9.26 | 23.53 | 8.58 | 13.8 | 21.57 | 30.22 | 1.22 | 1.54 | 1.95 | 2.49 | 4.09 | 5.89 | 7.47 | 8.8 | 10.05 | 20.33 | 36.02 | 55.4 | 18.21 | 29.17 | 41.05 | 57.27 | 1.36 | 1.72 | 2.21 | 2.74 |
BCL2 | ENSG00000171791 | 28 | 0.19 | 0.29 | 0.46 | 0.75 | 0.56 | 0.92 | 1.59 | 2.7 | 4.31 | 10.2 | 18.63 | 28.44 | 0.78 | 1.41 | 2.26 | 3.94 | 1.5 | 2.62 | 4.39 | 7.74 | 0.72 | 1.25 | 2.13 | 3.23 | 3.3 | 8.18 | 19.17 | 27.48 | 0.75 | 1.4 | 2.21 | 3.45 | 2 | 2.52 | 3.51 | 4.68 | 0.57 | 0.98 | 2 | 3.8 | 7.22 | 11.4 | 15.43 | 18.81 | 7.96 | 13.29 | 19.4 | 24.93 | 6.37 | 9.17 | 13.39 | 20.02 | 8.84 | 13.05 | 19.01 | 28.25 | 3.39 | 4.45 | 5.75 | 7.41 | 0.31 | 0.54 | 0.92 | 1.49 | 0.95 | 1.69 | 2.59 | 4.19 | 1.28 | 2.42 | 4.45 | 8.19 | 0.93 | 1.3 | 1.71 | 2.57 | 0.68 | 1.2 | 2.29 | 3.49 | 0.86 | 1.48 | 2.57 | 4.25 | 1.4 | 2.72 | 4.28 | 6.88 | 1.57 | 2.64 | 4.16 | 6.14 | 0.64 | 1.12 | 1.68 | 2.46 | 2.04 | 3.36 | 5.34 | 9.46 | 3.21 | 5.08 | 9.01 | 13 | 1.09 | 1.92 | 3.42 | 5.74 | 0.56 | 0.94 | 1.69 | 2.53 | 4 | 6.25 | 9.73 | 17.13 | 5.26 | 7.79 | 11.22 | 20.58 | 1.09 | 2.07 | 4.19 | 7.23 | 1.28 | 2.08 | 4.01 | 6.07 | 9.71 | 13.31 | 19.51 | 25.21 |
TOP2A | ENSG00000131747 | 32 | 2.91 | 6.98 | 17.01 | 33.44 | 28.37 | 44.69 | 67.57 | 95.92 | 12.12 | 23.85 | 42.91 | 70.56 | 43.2 | 60.81 | 82.42 | 127.6 | 5.88 | 10.42 | 15.9 | 29.96 | 27.51 | 36.32 | 46.54 | 63.09 | 37.17 | 47.38 | 69.6 | 85.16 | 33.07 | 45.86 | 71.32 | 120.36 | 14.91 | 24.92 | 39.51 | 55.09 | 19.12 | 30.69 | 45.29 | 61.78 | 0.56 | 0.87 | 1.96 | 3.39 | 2.46 | 3.67 | 6.48 | 10.54 | 1.55 | 2.72 | 5.31 | 15.57 | 12.92 | 21.38 | 33.04 | 48.85 | 1.56 | 3.65 | 9.62 | 22.42 | 3.49 | 9.05 | 21.42 | 39.47 | 9.84 | 19.84 | 36.99 | 58.23 | 21.99 | 34.73 | 50.92 | 75.79 | 8.82 | 16.15 | 27.34 | 43.8 | 13.67 | 22.07 | 36.62 | 54.33 | 6.41 | 9.74 | 15.9 | 23.29 | 1.06 | 1.95 | 3.71 | 5.52 | 1.81 | 2.98 | 5.23 | 10.03 | 25.02 | 38.89 | 53.45 | 69.16 | 17.75 | 37.14 | 56.32 | 90.68 | 11.82 | 18.83 | 30.27 | 42.55 | 19.73 | 32.41 | 55.84 | 94.66 | 34.07 | 47.96 | 63.4 | 84.62 | 1.46 | 2.4 | 3.84 | 5.82 | 24.82 | 79.5 | 150.34 | 202.42 | 28.84 | 46.37 | 74.3 | 116.16 | 45.18 | 63.87 | 95.12 | 122.39 | 1.06 | 2.22 | 3.68 | 5.79 |
MET | ENSG00000105976 | 28 | 0.38 | 0.88 | 1.62 | 3.47 | 6.53 | 10.73 | 17.9 | 26.56 | 1.12 | 2.44 | 5.21 | 9.41 | 7.12 | 11.98 | 17.78 | 24.89 | 9.6 | 15.54 | 20.63 | 29.89 | 18.37 | 24.74 | 34.26 | 48.31 | 0.32 | 0.86 | 2.1 | 5.14 | 12.2 | 20.73 | 31.18 | 47.59 | 0.55 | 1.28 | 3.56 | 7.09 | 9.91 | 14.56 | 22.08 | 31.77 | 25.81 | 44.37 | 64.78 | 82.08 | 28.99 | 39.71 | 55.72 | 76.15 | 43.44 | 69.74 | 107.96 | 169.01 | 0.01 | 0.06 | 0.14 | 0.24 | 0.12 | 0.29 | 0.78 | 2.1 | 9.85 | 15.22 | 22.8 | 29.19 | 12.15 | 25.08 | 48.89 | 104.91 | 11.08 | 17.83 | 25.79 | 33.13 | 11.27 | 25.46 | 45.9 | 65.13 | 1.45 | 2.82 | 5.52 | 9.24 | 12.23 | 18.6 | 29.49 | 47.94 | 0.33 | 0.56 | 1.02 | 2.22 | 1.13 | 2.22 | 3.94 | 6.01 | 18.6 | 26.34 | 33.11 | 39.82 | 1 | 1.94 | 5.02 | 12.89 | 3.38 | 10.23 | 25.86 | 52.98 | 10.33 | 17.49 | 26.84 | 43.01 | 0.81 | 1.87 | 3.41 | 5.77 | 29.56 | 69.25 | 100.35 | 130.56 | 2.11 | 4.99 | 11.52 | 17.72 | 4.03 | 7.59 | 16.57 | 32.26 | 4.64 | 6.84 | 11.77 | 16.01 | 25.64 | 47.21 | 81.91 | 113.51 |
FGFR2 | ENSG00000066468 | 29 | 1.48 | 3.2 | 7.01 | 12.74 | 3.05 | 6.41 | 13.5 | 22.61 | 4.49 | 9.03 | 16.36 | 28.75 | 4.31 | 8.26 | 14.69 | 24.62 | 24.73 | 49.41 | 83.61 | 121.84 | 1.33 | 2.94 | 6.46 | 11.69 | 0.1 | 0.28 | 0.48 | 0.9 | 5.05 | 10.66 | 18.78 | 35.77 | 7.57 | 11.43 | 19.54 | 38.14 | 5.43 | 8.76 | 17.05 | 31.04 | 3.17 | 6.05 | 10.95 | 14.04 | 4.62 | 7.65 | 11.72 | 17.15 | 4.27 | 7.13 | 12.06 | 18.06 | 0.01 | 0.05 | 0.18 | 0.45 | 11.84 | 21.01 | 34.21 | 59.76 | 1.06 | 7.53 | 24.16 | 44.7 | 2.41 | 4.59 | 8.58 | 14.64 | 10.93 | 22.24 | 41.05 | 67.38 | 3.09 | 5.15 | 8.03 | 11.61 | 11.77 | 18.7 | 28.08 | 39.63 | 4.68 | 7.4 | 12.01 | 17.25 | 0.16 | 0.85 | 2.71 | 6.38 | 2.73 | 5.85 | 11.2 | 16.45 | 1.08 | 2.35 | 4.64 | 8.48 | 0.71 | 4.13 | 13.94 | 25.16 | 0.04 | 0.12 | 0.36 | 1.3 | 5.1 | 9.74 | 17.1 | 28.87 | 9.89 | 16.13 | 22.82 | 34.96 | 9.07 | 14.39 | 21.33 | 28.69 | 3.86 | 6.64 | 13.55 | 23.64 | 7.52 | 17.46 | 44.79 | 71.14 | 4.67 | 12.83 | 26.11 | 43.33 | 0.37 | 1.16 | 2.51 | 3.03 |
RAD51 | ENSG00000051180 | 28 | 0.68 | 1.47 | 3.6 | 7.7 | 6.41 | 9.37 | 13.23 | 17.06 | 3.33 | 5.87 | 9.8 | 13.98 | 10.93 | 14.92 | 19.24 | 23.91 | 2.62 | 3.38 | 5.21 | 7.97 | 7.36 | 10.68 | 14.96 | 18.89 | 11.8 | 15.23 | 23.42 | 27.28 | 4.94 | 7.14 | 11.3 | 14.3 | 3.28 | 5.15 | 7.42 | 10.2 | 7.39 | 10.44 | 14.51 | 19.83 | 0.38 | 0.54 | 0.8 | 1.52 | 0.96 | 1.34 | 1.96 | 2.66 | 0.66 | 0.99 | 1.57 | 2.37 | 5.73 | 8.1 | 10.9 | 14.64 | 0.58 | 0.95 | 1.78 | 3.96 | 0.71 | 1.55 | 3.01 | 5.37 | 2.15 | 3.83 | 6.53 | 9.45 | 7.66 | 11.09 | 15.32 | 19.7 | 2.22 | 3.37 | 6.41 | 9.07 | 4.31 | 6.48 | 8.78 | 12.27 | 2.07 | 3.03 | 4.42 | 6.08 | 0.4 | 0.72 | 1.13 | 1.54 | 0.81 | 1.19 | 1.83 | 3.14 | 6.89 | 9.3 | 13.96 | 20.22 | 4.03 | 6.83 | 10.19 | 13.97 | 4.41 | 7.06 | 10.07 | 13.01 | 4.46 | 6.69 | 10.22 | 13.56 | 18.82 | 33.65 | 52.62 | 70.02 | 0.69 | 0.99 | 1.32 | 1.81 | 4.67 | 12.59 | 18.99 | 24.59 | 5.39 | 8.39 | 12.22 | 16.96 | 5.94 | 7.58 | 9.59 | 12.12 | 1.08 | 1.52 | 2.25 | 2.88 |
BUB1B | ENSG00000156970 | 27 | 0.89 | 1.71 | 3.6 | 7.79 | 4.67 | 7.58 | 10.69 | 14.25 | 2.93 | 5.22 | 8.62 | 13.03 | 8.76 | 12.18 | 15.92 | 20.61 | 1.87 | 3.24 | 5.32 | 7.87 | 6.58 | 9.56 | 12.46 | 15.81 | 8.09 | 14.26 | 21.27 | 28.24 | 7.41 | 10.83 | 15.26 | 20.76 | 3.08 | 4.32 | 6.68 | 9.82 | 4.65 | 7.46 | 10.95 | 14.43 | 0.46 | 0.65 | 1.05 | 1.94 | 0.65 | 0.99 | 1.5 | 2.17 | 0.42 | 0.65 | 1.06 | 2.08 | 10.62 | 16.67 | 22.66 | 27.64 | 0.49 | 1.08 | 2.09 | 4.96 | 0.6 | 1.38 | 3.34 | 5.28 | 1.77 | 3.56 | 6.44 | 10.1 | 6.6 | 9.56 | 13.45 | 18.33 | 1.68 | 2.75 | 5.75 | 8.19 | 3.83 | 5.56 | 8.52 | 11.8 | 1.71 | 2.5 | 3.68 | 4.97 | 0.33 | 0.52 | 0.9 | 1.52 | 0.7 | 1.06 | 1.67 | 2.74 | 5.71 | 8.68 | 11.46 | 15.7 | 3.14 | 6.66 | 10.88 | 18.21 | 3.78 | 6.15 | 9.68 | 12.98 | 4.68 | 7.35 | 11.49 | 15.65 | 13.61 | 19.8 | 29.68 | 39.65 | 0.63 | 0.9 | 1.33 | 1.76 | 4.01 | 10.83 | 22.33 | 28.81 | 5.82 | 10.36 | 15.23 | 20.88 | 8.65 | 10.72 | 14.11 | 21.76 | 0.54 | 0.86 | 1.33 | 2.09 |
ERBB2 | ENSG00000141736 | 33 | 1.12 | 1.78 | 3.1 | 5.95 | 41.94 | 77.18 | 126.48 | 212.72 | 51.77 | 82.52 | 129.58 | 301.83 | 35.77 | 49.53 | 72.32 | 112.96 | 34.62 | 57.94 | 74.64 | 86.31 | 42.86 | 55.47 | 69.12 | 82.31 | 2.19 | 2.54 | 3.19 | 4.32 | 27.38 | 47.52 | 80.13 | 158.53 | 7.5 | 13.23 | 21.14 | 28.63 | 23.54 | 32.28 | 43.97 | 58.71 | 27.21 | 37.41 | 56.62 | 64.68 | 19.53 | 28.31 | 37.92 | 50.54 | 48.4 | 68.12 | 94.38 | 118.13 | 1.16 | 1.6 | 2.35 | 3.17 | 5.94 | 7.39 | 9.36 | 15.85 | 8.95 | 16.78 | 30.03 | 43.52 | 45.93 | 66.97 | 95.03 | 127.31 | 21.63 | 30.48 | 41.39 | 54.75 | 21.37 | 28.23 | 40.55 | 54.81 | 32.43 | 42.83 | 61.58 | 81.33 | 35.02 | 54.76 | 67.99 | 89.59 | 1.88 | 2.45 | 3.54 | 5.14 | 48.48 | 60.12 | 75.02 | 90.17 | 37.49 | 50.57 | 67.66 | 86.98 | 9.5 | 14.99 | 20.48 | 30.46 | 9.23 | 14.93 | 21.53 | 30.38 | 33.94 | 50.01 | 77.75 | 171.05 | 10.98 | 20.2 | 34.93 | 56.84 | 55.85 | 68.59 | 87.91 | 107.57 | 4.04 | 8.05 | 17.97 | 36.16 | 39.16 | 54.9 | 79.08 | 132.2 | 33.73 | 46.85 | 70.11 | 125.16 | 13.32 | 16.49 | 20.28 | 26.01 |
BIRC5 | ENSG00000089685 | 30 | 1.25 | 4.28 | 10.07 | 23.65 | 13.81 | 25.27 | 35.37 | 46.53 | 6.38 | 12.88 | 24.08 | 40.2 | 22.45 | 30.37 | 42.57 | 56.16 | 4.43 | 7.63 | 12.38 | 20.18 | 17.75 | 25.08 | 34.93 | 45.01 | 22.77 | 39.05 | 50.4 | 56.18 | 9.15 | 15.46 | 21.34 | 27.02 | 13.36 | 20.59 | 30.99 | 50.3 | 17.94 | 26.39 | 35.83 | 47.85 | 0.43 | 0.72 | 1.85 | 3.9 | 1.35 | 1.95 | 3.15 | 5.13 | 0.79 | 1.24 | 2.26 | 6.49 | 5.37 | 8.47 | 12.03 | 16.9 | 0.92 | 2.12 | 5.14 | 14.64 | 2.35 | 5.97 | 12.9 | 23.19 | 5.37 | 11.68 | 22.51 | 36.53 | 21.01 | 33 | 44.76 | 61.51 | 4.84 | 8.9 | 18.51 | 29.75 | 12.46 | 20.66 | 31.74 | 50.79 | 3.45 | 4.99 | 8.04 | 13.87 | 0.52 | 0.93 | 1.58 | 2.93 | 1.24 | 2 | 3.64 | 7 | 16.29 | 23.21 | 34.23 | 44.95 | 9.64 | 19.97 | 34.94 | 53.69 | 11.42 | 17.96 | 26.02 | 36.59 | 8.46 | 12.85 | 19.58 | 27.32 | 24.1 | 31.46 | 42.15 | 52.77 | 0.5 | 0.79 | 1.26 | 1.89 | 11.91 | 35.83 | 64.73 | 79.66 | 15 | 27.08 | 42.2 | 61.93 | 28.32 | 36.93 | 44.93 | 57.18 | 1.53 | 2.98 | 4.79 | 5.77 |
CHEK1 | ENSG00000149554 | 33 | 1.48 | 2.25 | 4.61 | 7.76 | 6.12 | 9.63 | 14.6 | 19.72 | 3.48 | 5.65 | 9.79 | 16.41 | 10.78 | 15.11 | 20.34 | 25.68 | 4.28 | 6.88 | 9.26 | 11.47 | 11.1 | 15.1 | 18.83 | 23.88 | 15.64 | 24.19 | 32.97 | 46.92 | 6.24 | 9.58 | 13.5 | 19.05 | 5.36 | 8.08 | 11.34 | 15.58 | 6.91 | 9.78 | 13.51 | 18.3 | 1.74 | 2.4 | 3.07 | 4.25 | 2.39 | 3.3 | 4.52 | 6.54 | 2.13 | 2.82 | 4.27 | 5.64 | 10.98 | 15.68 | 19.47 | 24.72 | 1.56 | 2.29 | 3.74 | 6.97 | 1.1 | 2.13 | 4.36 | 7.63 | 2.83 | 5.52 | 9.17 | 15.16 | 8.16 | 11.71 | 15.4 | 20.21 | 4.07 | 6.4 | 9.4 | 13.55 | 5.35 | 7.69 | 11.91 | 16.85 | 2.61 | 3.67 | 5.07 | 6.95 | 1.11 | 1.57 | 2.21 | 3.43 | 1.83 | 2.29 | 3.01 | 3.87 | 10.02 | 14.6 | 20.33 | 25.28 | 4.57 | 6.9 | 11.17 | 15.76 | 4.14 | 6.44 | 9.73 | 14.26 | 5.95 | 9.35 | 13.28 | 19.2 | 13.55 | 18.97 | 27.1 | 33.79 | 1.5 | 2.02 | 2.56 | 3.05 | 6.25 | 13.9 | 23.73 | 26.7 | 6.75 | 11 | 15.54 | 19.74 | 10.92 | 13.19 | 17.39 | 21.47 | 1.6 | 2.13 | 2.67 | 3.36 |
CDK1 | ENSG00000170312 | 33 | 3.6 | 10.82 | 24.33 | 44.91 | 18.7 | 29.92 | 41.77 | 54.92 | 11.77 | 21.09 | 33.57 | 50.88 | 38.73 | 52.35 | 67.43 | 84.21 | 7.13 | 8.46 | 12.59 | 24.2 | 26.67 | 34.89 | 45.07 | 59.1 | 25.47 | 35.73 | 48.06 | 69.61 | 20.66 | 30.75 | 41.88 | 55.09 | 9.81 | 14.86 | 24.01 | 31.43 | 17.94 | 26.67 | 38.38 | 53.48 | 1.09 | 1.58 | 2.47 | 4.88 | 3.01 | 4.09 | 5.78 | 8.34 | 1.2 | 1.81 | 3.21 | 7.28 | 9.97 | 16.78 | 25.54 | 34.92 | 1.39 | 2.92 | 6.29 | 13.72 | 2.43 | 5.62 | 11.82 | 18.9 | 8.01 | 14.13 | 25.77 | 39.54 | 23.74 | 34.91 | 48.33 | 63.25 | 6.3 | 9.58 | 16.01 | 24.08 | 17.52 | 25.19 | 35.79 | 50.51 | 5.7 | 9.42 | 13.44 | 18.25 | 1.39 | 2.07 | 3.5 | 5.57 | 1.98 | 2.96 | 5.41 | 9.71 | 22.31 | 38.22 | 49.34 | 62.12 | 10.06 | 19.41 | 31.04 | 48.45 | 8.66 | 14.23 | 21.42 | 30.75 | 16.05 | 24.44 | 36.08 | 45.75 | 14.98 | 21.54 | 31.85 | 37.22 | 2.17 | 2.84 | 3.91 | 5.19 | 17.9 | 34.9 | 53.99 | 72.39 | 22.17 | 34.09 | 46.57 | 57.74 | 30.15 | 38.22 | 50.54 | 64.32 | 1.37 | 2.55 | 3.76 | 6.8 |
FGFR3 | ENSG00000068078 | 25 | 0.1 | 0.2 | 0.48 | 1.52 | 8.18 | 31.28 | 90.5 | 173.62 | 1.3 | 4.1 | 9.06 | 19.83 | 10.92 | 30.55 | 54.25 | 90.5 | 20.15 | 62.3 | 104.83 | 153.57 | 3.75 | 6.39 | 11.56 | 16.17 | 0.06 | 0.11 | 0.15 | 0.29 | 11.01 | 24.95 | 48.76 | 82.57 | 6.98 | 13.24 | 30.26 | 60.18 | 19.47 | 33.33 | 50.86 | 71.51 | 0.06 | 0.11 | 0.22 | 0.44 | 3.67 | 6.29 | 9.71 | 14.5 | 3.84 | 7.8 | 12.73 | 18.75 | 0.31 | 0.61 | 1.27 | 3.27 | 8.2 | 18.87 | 35.14 | 59.89 | 6.39 | 11.04 | 20.98 | 45.53 | 1.63 | 5 | 12.39 | 24.11 | 10.25 | 22.01 | 45.38 | 81.75 | 0.45 | 0.66 | 1.54 | 2.55 | 0.75 | 2.08 | 5.66 | 12.27 | 5.37 | 9.99 | 17.2 | 29.86 | 0.13 | 0.21 | 0.33 | 0.66 | 3.65 | 5.87 | 9.35 | 12.73 | 3.61 | 6.88 | 11.29 | 18.46 | 0.24 | 0.57 | 1.69 | 5.66 | 0.11 | 0.27 | 0.91 | 3.08 | 2.78 | 6.96 | 14.52 | 28.71 | 31.84 | 45.22 | 70.73 | 90.8 | 0.63 | 1.23 | 2.41 | 5.68 | 1.73 | 2.8 | 9.3 | 39.3 | 1.23 | 3.13 | 7.75 | 19.93 | 2.14 | 5.95 | 17.05 | 38.75 | 0.86 | 1.78 | 2.8 | 4.05 |
JAK2 | ENSG00000096968 | 31 | 1.12 | 1.56 | 2.05 | 2.9 | 1.32 | 2.07 | 3.43 | 5.39 | 2.54 | 3.82 | 5.35 | 7.46 | 2.07 | 3.43 | 5.43 | 7.9 | 1.16 | 1.68 | 2.96 | 4.35 | 1.91 | 2.77 | 4.07 | 6.39 | 3.05 | 5 | 8.49 | 17.19 | 2.48 | 4.4 | 6.77 | 11.37 | 2.08 | 2.82 | 3.4 | 4.3 | 1.52 | 2.55 | 4.24 | 6.77 | 1.88 | 2.66 | 3.57 | 4.29 | 2.88 | 3.88 | 5.11 | 6.61 | 1.39 | 2.09 | 2.8 | 3.68 | 11.34 | 15.86 | 22.19 | 28.86 | 2.42 | 2.99 | 3.75 | 4.7 | 0.55 | 0.81 | 1.24 | 1.98 | 2.03 | 3.04 | 4.42 | 5.91 | 1.86 | 2.75 | 3.9 | 5.51 | 2.04 | 3.11 | 4.11 | 5.45 | 0.97 | 1.49 | 2.11 | 2.7 | 2.62 | 3.86 | 5.08 | 6.85 | 2 | 2.74 | 3.51 | 4.82 | 1.55 | 2.16 | 2.79 | 3.44 | 1.73 | 2.55 | 3.5 | 4.42 | 2.65 | 3.99 | 6.61 | 10.58 | 1.29 | 2.28 | 3.81 | 5.99 | 3.17 | 5.48 | 8.74 | 13.8 | 1.41 | 2.07 | 3.19 | 4.45 | 1.39 | 1.77 | 2.25 | 2.81 | 1.55 | 2.53 | 3.46 | 5.11 | 1.01 | 1.5 | 2.42 | 3.57 | 0.91 | 1.3 | 1.72 | 2.92 | 0.43 | 0.93 | 1.46 | 2.61 |
CDK6 | ENSG00000105810 | 33 | 1.41 | 3.17 | 7.39 | 11.45 | 0.6 | 1.64 | 3.99 | 7.23 | 0.97 | 1.71 | 3.32 | 6.37 | 1.2 | 2.46 | 4.77 | 7.55 | 0.73 | 2.18 | 7.21 | 9.84 | 4.11 | 5.39 | 7.61 | 10.15 | 3.06 | 4.08 | 5.7 | 9.59 | 6.37 | 10.33 | 18.7 | 28.11 | 3.11 | 6.17 | 10.6 | 18.22 | 4.78 | 8.03 | 12.85 | 17.81 | 1.65 | 2.33 | 3.33 | 4.52 | 2.32 | 3.59 | 5.24 | 7.36 | 2.35 | 3.84 | 5.92 | 8.76 | 43.42 | 77.44 | 117.17 | 150.74 | 1.79 | 2.82 | 4.91 | 9.09 | 0.81 | 1.79 | 3.56 | 5.96 | 1.06 | 1.89 | 3.34 | 5.66 | 3.6 | 5.56 | 8.06 | 11.29 | 4.07 | 6.94 | 10.48 | 16.67 | 0.73 | 1.79 | 3.31 | 5.3 | 3.55 | 5.24 | 6.72 | 8.36 | 2.52 | 3.66 | 5.04 | 7.09 | 1.49 | 2.56 | 4.03 | 6.47 | 4.05 | 5.75 | 7.64 | 9.71 | 0.83 | 2.55 | 5.3 | 9.05 | 3.01 | 5.96 | 10.67 | 16.5 | 4.99 | 7.85 | 11.56 | 18.15 | 1.2 | 2.55 | 5.93 | 9.31 | 0.74 | 1.1 | 1.57 | 2.18 | 4.34 | 11.85 | 18.25 | 22.95 | 0.55 | 1.2 | 2.56 | 4.39 | 3.47 | 4.71 | 8.1 | 11.53 | 0.68 | 1.25 | 2.18 | 3.45 |
PLK1 | ENSG00000166851 | 30 | 1.13 | 3.46 | 9.07 | 16.81 | 12.2 | 21.56 | 34.33 | 47.46 | 5.78 | 10.84 | 20.13 | 32.2 | 23.23 | 31.91 | 40.56 | 50.15 | 4.82 | 7.43 | 10.18 | 14.49 | 21.35 | 29.06 | 38.66 | 47.04 | 28.06 | 40.26 | 50.88 | 72.24 | 19.78 | 29.18 | 42.18 | 56.04 | 8.05 | 12.85 | 17.98 | 26.54 | 18.92 | 27.45 | 36.73 | 47.12 | 0.46 | 0.7 | 1.62 | 3.1 | 1.14 | 1.71 | 2.65 | 4.8 | 1.05 | 1.55 | 2.33 | 4.56 | 8.66 | 15.31 | 23.38 | 34.06 | 1.63 | 2.58 | 4.32 | 9.21 | 1.35 | 3.4 | 7.89 | 13.78 | 5.05 | 9.8 | 17.31 | 27.12 | 16.5 | 22.6 | 30.33 | 39.83 | 4.55 | 8.5 | 15.84 | 21.54 | 16.85 | 23.66 | 35.29 | 50.85 | 5.24 | 9.08 | 13.77 | 18.23 | 0.61 | 0.84 | 1.34 | 1.84 | 0.96 | 1.47 | 2.47 | 4.17 | 18.18 | 26.89 | 37.26 | 46.17 | 6.38 | 13.86 | 23.28 | 33.54 | 10.54 | 16.9 | 25.42 | 37.38 | 17.59 | 26.39 | 37.9 | 53.66 | 22.02 | 34.22 | 50.6 | 70.94 | 0.64 | 0.92 | 1.35 | 1.94 | 7.79 | 23.92 | 42.66 | 56.1 | 10.95 | 20.31 | 28.22 | 39.15 | 18.96 | 27.31 | 33.08 | 42.12 | 1.68 | 3.5 | 4.88 | 7.15 |
AURKA | ENSG00000087586 | 33 | 3.01 | 6.26 | 10.82 | 21.4 | 8.91 | 15.87 | 22.78 | 30.94 | 5.31 | 10.04 | 17.96 | 27.9 | 14.62 | 20.65 | 27.42 | 34.34 | 3.85 | 6.09 | 8.22 | 12.04 | 18.25 | 25.88 | 35.91 | 46.97 | 14.94 | 18.85 | 26.02 | 34.92 | 11.1 | 16.16 | 25.31 | 34.03 | 4.97 | 7.43 | 11.11 | 14.11 | 10.88 | 15.77 | 21.79 | 29.85 | 3.71 | 4.95 | 6.67 | 9.89 | 1.8 | 2.32 | 3.25 | 4.81 | 1.84 | 2.47 | 3.87 | 6.52 | 4.46 | 7.04 | 11.07 | 14.37 | 1 | 1.47 | 2.56 | 5.69 | 3.81 | 6.77 | 12.56 | 19.94 | 4.59 | 9.39 | 16.4 | 26.47 | 12.35 | 16.82 | 23.35 | 30.87 | 3.23 | 5.59 | 9.47 | 15.19 | 8.98 | 14.11 | 20.92 | 28.7 | 3.25 | 4.84 | 7.05 | 9.69 | 1.17 | 1.69 | 2.86 | 5.16 | 1.07 | 1.45 | 2.23 | 3.66 | 18.19 | 27.7 | 40.94 | 50.7 | 4.95 | 10.1 | 18.17 | 25.2 | 9.25 | 13.99 | 20.65 | 30.92 | 11.36 | 17.58 | 26.72 | 36.16 | 16.05 | 21.75 | 29.79 | 36.49 | 0.77 | 1.03 | 1.41 | 2.02 | 5.18 | 9.99 | 15.77 | 21.46 | 8.51 | 13.29 | 20.34 | 27.51 | 15.61 | 20.62 | 27.11 | 33.07 | 1.79 | 3 | 4.44 | 5.87 |
TTK | ENSG00000112742 | 25 | 0.81 | 1.86 | 3.87 | 7.82 | 3.91 | 6.08 | 9.42 | 13.99 | 2.14 | 3.71 | 7.18 | 12.44 | 7.2 | 10.01 | 13.37 | 16.5 | 0.91 | 1.29 | 2.18 | 4.86 | 5.54 | 7.33 | 9.43 | 12.37 | 3.37 | 4.74 | 6.92 | 9.32 | 5.98 | 8.57 | 11.56 | 15.99 | 2.15 | 3.5 | 5.5 | 8.55 | 4.37 | 6.53 | 9.81 | 13.12 | 0.33 | 0.61 | 0.88 | 1.62 | 0.45 | 0.65 | 0.96 | 1.47 | 0.23 | 0.35 | 0.65 | 1.36 | 3.52 | 5.53 | 8 | 10.81 | 0.25 | 0.52 | 1.19 | 2.83 | 0.43 | 1.06 | 2.33 | 4.73 | 1.14 | 2.51 | 4.87 | 8.35 | 5.78 | 8.57 | 11.66 | 15.3 | 1.09 | 2.19 | 3.61 | 5.57 | 4.67 | 7.2 | 11.03 | 14.82 | 0.88 | 1.48 | 2.12 | 3.48 | 0.2 | 0.34 | 0.6 | 0.97 | 0.58 | 0.9 | 1.69 | 2.77 | 5.61 | 8.09 | 11.27 | 14.95 | 2.01 | 3.82 | 7.98 | 11.19 | 1.9 | 3.02 | 5.15 | 7.79 | 3.68 | 6.38 | 9.82 | 14.37 | 9.91 | 14.4 | 20.15 | 23.22 | 0.28 | 0.4 | 0.57 | 0.8 | 2.35 | 9.95 | 22.68 | 33.62 | 4.43 | 7.6 | 12.02 | 16.26 | 7.46 | 11.14 | 13.37 | 20.35 | 0.25 | 0.45 | 0.72 | 1.13 |
ESR1 | ENSG00000091831 | 6 | 0.08 | 0.21 | 0.5 | 0.88 | 0.14 | 0.33 | 0.78 | 1.84 | 9.57 | 53.22 | 120.7 | 212.09 | 0.68 | 1.9 | 5.67 | 13.73 | 0.09 | 0.18 | 0.42 | 0.64 | 0.04 | 0.08 | 0.18 | 0.33 | 0.15 | 0.33 | 0.53 | 0.82 | 0.12 | 0.2 | 0.42 | 0.86 | 0.12 | 0.18 | 0.28 | 0.42 | 0.15 | 0.31 | 0.67 | 1.62 | 0.08 | 0.16 | 0.31 | 0.64 | 0.58 | 0.95 | 1.5 | 2.13 | 0.25 | 0.57 | 1.03 | 1.73 | 0.33 | 0.52 | 1.17 | 1.88 | 0.1 | 0.16 | 0.23 | 0.34 | 0.12 | 0.43 | 1.45 | 3.79 | 0.46 | 0.99 | 1.94 | 4.33 | 0.16 | 0.3 | 0.68 | 1.61 | 0.16 | 0.26 | 0.41 | 0.54 | 8.87 | 15.34 | 23.59 | 35.62 | 0.2 | 0.34 | 0.68 | 1.1 | 0.12 | 0.21 | 0.32 | 0.5 | 0.88 | 1.54 | 2.76 | 4.2 | 0.04 | 0.08 | 0.15 | 0.34 | 0.27 | 0.63 | 1.4 | 7.99 | 0.15 | 0.3 | 0.53 | 0.8 | 0.14 | 0.27 | 0.54 | 0.84 | 0.15 | 0.21 | 0.35 | 0.48 | 0.83 | 1.66 | 3.26 | 8.95 | 0.18 | 0.29 | 0.75 | 1.28 | 9.7 | 31.64 | 56.08 | 88.72 | 0.48 | 0.72 | 1.8 | 6.98 | 0.24 | 0.51 | 1.11 | 1.82 |
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