Expression

 

Positive expression of a PDG in a given cancer type was defined as its mRNA expression was reliably detected in at least 50% of tumor specimens (i.e., the 50th percentile of fragments per kilobase of transcript per million mapped reads [FPKM] value ≥1).

 

Summary of PDG mRNA expression levels (FPKM value) in each cancer type


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HGNC Ensembl No. Detectable ACCBLCABRCACESCCHOLCOADDLBCESCAGBMHNSCKICHKIRCKIRPLAMLLGGLIHCLUADLUSCMESOOVPAADPCPGPRADREADSARCSKCMSTADTGCTTHCATHYMUCECUCSUVM
SymbolGene IDCancer Types25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th
EGFRENSG00000146648281.613.777.8213.044.9210.0419.3337.441.032.355.1610.067.5315.1524.6538.076.89.2512.8321.285.066.679.1712.230.260.460.841.4513.7726.6252.1499.4714.0955.61247.86476.7618.829.8244.4874.363.867.5314.6523.0119.0329.3342.2961.426.2310.0715.3421.7300.010.070.1518.4833.6151.1199.3457.7212.7820.996.812.5722.4138.8614.9523.193657.077.2613.4321.8636.961.893.335.6885.827.6110.3414.310.210.481.143.167.0610.2814.1718.345.457.119.2710.773.556.1311.318.660.160.41.12.796.6310.1714.0722.260.821.533.016.057.7311.9517.4423.75.3510.9220.8931.692.13.746.179.832.55.938.1214.770.190.30.510.8
FLT3ENSG0000012202510.010.030.080.170.020.060.160.340.220.632.054.990.040.10.210.390.050.110.460.970.030.080.170.270.150.310.721.280.040.080.180.30.030.070.130.260.050.120.270.5100.010.040.10.190.350.611.090.070.190.481.5642.8676.74113.97152.580.070.130.230.430.020.060.140.270.120.250.430.680.060.150.280.50.220.511.282.930.020.060.120.210.160.561.232.140.020.030.070.140.060.120.220.380.040.080.140.260.030.090.230.660.040.10.260.540.060.140.270.50.190.30.510.680.020.070.160.370.50.81.2620.020.060.130.250.020.040.10.2600.010.030.07
CCNE1ENSG00000105173318.6415.0524.139.497.3112.1721.9633.061.262.164.6112.718.1411.2414.9219.692.693.935.388.14.726.939.7413.1210.4913.2216.6824.644.136.179.3816.142.273.335.297.824.126.168.7712.1911.231.792.120.610.811.261.820.841.211.873.144.417.3210.5513.61.291.732.43.30.671.363.387.691.843.246.7312.784.827.2112.0418.261.322.293.265.2310.0717.430.4949.682.052.83.755.891.3723.014.540.640.851.181.594.71710.6714.992.98612.6721.83.695.427.7511.463.025.269.2623.538.5813.821.5730.221.221.541.952.494.095.897.478.810.0520.3336.0255.418.2129.1741.0557.271.361.722.212.74
BCL2ENSG00000171791280.190.290.460.750.560.921.592.74.3110.218.6328.440.781.412.263.941.52.624.397.740.721.252.133.233.38.1819.1727.480.751.42.213.4522.523.514.680.570.9823.87.2211.415.4318.817.9613.2919.424.936.379.1713.3920.028.8413.0519.0128.253.394.455.757.410.310.540.921.490.951.692.594.191.282.424.458.190.931.31.712.570.681.22.293.490.861.482.574.251.42.724.286.881.572.644.166.140.641.121.682.462.043.365.349.463.215.089.01131.091.923.425.740.560.941.692.5346.259.7317.135.267.7911.2220.581.092.074.197.231.282.084.016.079.7113.3119.5125.21
TOP2AENSG00000131747322.916.9817.0133.4428.3744.6967.5795.9212.1223.8542.9170.5643.260.8182.42127.65.8810.4215.929.9627.5136.3246.5463.0937.1747.3869.685.1633.0745.8671.32120.3614.9124.9239.5155.0919.1230.6945.2961.780.560.871.963.392.463.676.4810.541.552.725.3115.5712.9221.3833.0448.851.563.659.6222.423.499.0521.4239.479.8419.8436.9958.2321.9934.7350.9275.798.8216.1527.3443.813.6722.0736.6254.336.419.7415.923.291.061.953.715.521.812.985.2310.0325.0238.8953.4569.1617.7537.1456.3290.6811.8218.8330.2742.5519.7332.4155.8494.6634.0747.9663.484.621.462.43.845.8224.8279.5150.34202.4228.8446.3774.3116.1645.1863.8795.12122.391.062.223.685.79
METENSG00000105976280.380.881.623.476.5310.7317.926.561.122.445.219.417.1211.9817.7824.899.615.5420.6329.8918.3724.7434.2648.310.320.862.15.1412.220.7331.1847.590.551.283.567.099.9114.5622.0831.7725.8144.3764.7882.0828.9939.7155.7276.1543.4469.74107.96169.010.010.060.140.240.120.290.782.19.8515.2222.829.1912.1525.0848.89104.9111.0817.8325.7933.1311.2725.4645.965.131.452.825.529.2412.2318.629.4947.940.330.561.022.221.132.223.946.0118.626.3433.1139.8211.945.0212.893.3810.2325.8652.9810.3317.4926.8443.010.811.873.415.7729.5669.25100.35130.562.114.9911.5217.724.037.5916.5732.264.646.8411.7716.0125.6447.2181.91113.51
FGFR2ENSG00000066468291.483.27.0112.743.056.4113.522.614.499.0316.3628.754.318.2614.6924.6224.7349.4183.61121.841.332.946.4611.690.10.280.480.95.0510.6618.7835.777.5711.4319.5438.145.438.7617.0531.043.176.0510.9514.044.627.6511.7217.154.277.1312.0618.060.010.050.180.4511.8421.0134.2159.761.067.5324.1644.72.414.598.5814.6410.9322.2441.0567.383.095.158.0311.6111.7718.728.0839.634.687.412.0117.250.160.852.716.382.735.8511.216.451.082.354.648.480.714.1313.9425.160.040.120.361.35.19.7417.128.879.8916.1322.8234.969.0714.3921.3328.693.866.6413.5523.647.5217.4644.7971.144.6712.8326.1143.330.371.162.513.03
RAD51ENSG00000051180280.681.473.67.76.419.3713.2317.063.335.879.813.9810.9314.9219.2423.912.623.385.217.977.3610.6814.9618.8911.815.2323.4227.284.947.1411.314.33.285.157.4210.27.3910.4414.5119.830.380.540.81.520.961.341.962.660.660.991.572.375.738.110.914.640.580.951.783.960.711.553.015.372.153.836.539.457.6611.0915.3219.72.223.376.419.074.316.488.7812.272.073.034.426.080.40.721.131.540.811.191.833.146.899.313.9620.224.036.8310.1913.974.417.0610.0713.014.466.6910.2213.5618.8233.6552.6270.020.690.991.321.814.6712.5918.9924.595.398.3912.2216.965.947.589.5912.121.081.522.252.88
BUB1BENSG00000156970270.891.713.67.794.677.5810.6914.252.935.228.6213.038.7612.1815.9220.611.873.245.327.876.589.5612.4615.818.0914.2621.2728.247.4110.8315.2620.763.084.326.689.824.657.4610.9514.430.460.651.051.940.650.991.52.170.420.651.062.0810.6216.6722.6627.640.491.082.094.960.61.383.345.281.773.566.4410.16.69.5613.4518.331.682.755.758.193.835.568.5211.81.712.53.684.970.330.520.91.520.71.061.672.745.718.6811.4615.73.146.6610.8818.213.786.159.6812.984.687.3511.4915.6513.6119.829.6839.650.630.91.331.764.0110.8322.3328.815.8210.3615.2320.888.6510.7214.1121.760.540.861.332.09
ERBB2ENSG00000141736331.121.783.15.9541.9477.18126.48212.7251.7782.52129.58301.8335.7749.5372.32112.9634.6257.9474.6486.3142.8655.4769.1282.312.192.543.194.3227.3847.5280.13158.537.513.2321.1428.6323.5432.2843.9758.7127.2137.4156.6264.6819.5328.3137.9250.5448.468.1294.38118.131.161.62.353.175.947.399.3615.858.9516.7830.0343.5245.9366.9795.03127.3121.6330.4841.3954.7521.3728.2340.5554.8132.4342.8361.5881.3335.0254.7667.9989.591.882.453.545.1448.4860.1275.0290.1737.4950.5767.6686.989.514.9920.4830.469.2314.9321.5330.3833.9450.0177.75171.0510.9820.234.9356.8455.8568.5987.91107.574.048.0517.9736.1639.1654.979.08132.233.7346.8570.11125.1613.3216.4920.2826.01
BIRC5ENSG00000089685301.254.2810.0723.6513.8125.2735.3746.536.3812.8824.0840.222.4530.3742.5756.164.437.6312.3820.1817.7525.0834.9345.0122.7739.0550.456.189.1515.4621.3427.0213.3620.5930.9950.317.9426.3935.8347.850.430.721.853.91.351.953.155.130.791.242.266.495.378.4712.0316.90.922.125.1414.642.355.9712.923.195.3711.6822.5136.5321.013344.7661.514.848.918.5129.7512.4620.6631.7450.793.454.998.0413.870.520.931.582.931.2423.64716.2923.2134.2344.959.6419.9734.9453.6911.4217.9626.0236.598.4612.8519.5827.3224.131.4642.1552.770.50.791.261.8911.9135.8364.7379.661527.0842.261.9328.3236.9344.9357.181.532.984.795.77
CHEK1ENSG00000149554331.482.254.617.766.129.6314.619.723.485.659.7916.4110.7815.1120.3425.684.286.889.2611.4711.115.118.8323.8815.6424.1932.9746.926.249.5813.519.055.368.0811.3415.586.919.7813.5118.31.742.43.074.252.393.34.526.542.132.824.275.6410.9815.6819.4724.721.562.293.746.971.12.134.367.632.835.529.1715.168.1611.7115.420.214.076.49.413.555.357.6911.9116.852.613.675.076.951.111.572.213.431.832.293.013.8710.0214.620.3325.284.576.911.1715.764.146.449.7314.265.959.3513.2819.213.5518.9727.133.791.52.022.563.056.2513.923.7326.76.751115.5419.7410.9213.1917.3921.471.62.132.673.36
CDK1ENSG00000170312333.610.8224.3344.9118.729.9241.7754.9211.7721.0933.5750.8838.7352.3567.4384.217.138.4612.5924.226.6734.8945.0759.125.4735.7348.0669.6120.6630.7541.8855.099.8114.8624.0131.4317.9426.6738.3853.481.091.582.474.883.014.095.788.341.21.813.217.289.9716.7825.5434.921.392.926.2913.722.435.6211.8218.98.0114.1325.7739.5423.7434.9148.3363.256.39.5816.0124.0817.5225.1935.7950.515.79.4213.4418.251.392.073.55.571.982.965.419.7122.3138.2249.3462.1210.0619.4131.0448.458.6614.2321.4230.7516.0524.4436.0845.7514.9821.5431.8537.222.172.843.915.1917.934.953.9972.3922.1734.0946.5757.7430.1538.2250.5464.321.372.553.766.8
FGFR3ENSG00000068078250.10.20.481.528.1831.2890.5173.621.34.19.0619.8310.9230.5554.2590.520.1562.3104.83153.573.756.3911.5616.170.060.110.150.2911.0124.9548.7682.576.9813.2430.2660.1819.4733.3350.8671.510.060.110.220.443.676.299.7114.53.847.812.7318.750.310.611.273.278.218.8735.1459.896.3911.0420.9845.531.63512.3924.1110.2522.0145.3881.750.450.661.542.550.752.085.6612.275.379.9917.229.860.130.210.330.663.655.879.3512.733.616.8811.2918.460.240.571.695.660.110.270.913.082.786.9614.5228.7131.8445.2270.7390.80.631.232.415.681.732.89.339.31.233.137.7519.932.145.9517.0538.750.861.782.84.05
JAK2ENSG00000096968311.121.562.052.91.322.073.435.392.543.825.357.462.073.435.437.91.161.682.964.351.912.774.076.393.0558.4917.192.484.46.7711.372.082.823.44.31.522.554.246.771.882.663.574.292.883.885.116.611.392.092.83.6811.3415.8622.1928.862.422.993.754.70.550.811.241.982.033.044.425.911.862.753.95.512.043.114.115.450.971.492.112.72.623.865.086.8522.743.514.821.552.162.793.441.732.553.54.422.653.996.6110.581.292.283.815.993.175.488.7413.81.412.073.194.451.391.772.252.811.552.533.465.111.011.52.423.570.911.31.722.920.430.931.462.61
CDK6ENSG00000105810331.413.177.3911.450.61.643.997.230.971.713.326.371.22.464.777.550.732.187.219.844.115.397.6110.153.064.085.79.596.3710.3318.728.113.116.1710.618.224.788.0312.8517.811.652.333.334.522.323.595.247.362.353.845.928.7643.4277.44117.17150.741.792.824.919.090.811.793.565.961.061.893.345.663.65.568.0611.294.076.9410.4816.670.731.793.315.33.555.246.728.362.523.665.047.091.492.564.036.474.055.757.649.710.832.555.39.053.015.9610.6716.54.997.8511.5618.151.22.555.939.310.741.11.572.184.3411.8518.2522.950.551.22.564.393.474.718.111.530.681.252.183.45
PLK1ENSG00000166851301.133.469.0716.8112.221.5634.3347.465.7810.8420.1332.223.2331.9140.5650.154.827.4310.1814.4921.3529.0638.6647.0428.0640.2650.8872.2419.7829.1842.1856.048.0512.8517.9826.5418.9227.4536.7347.120.460.71.623.11.141.712.654.81.051.552.334.568.6615.3123.3834.061.632.584.329.211.353.47.8913.785.059.817.3127.1216.522.630.3339.834.558.515.8421.5416.8523.6635.2950.855.249.0813.7718.230.610.841.341.840.961.472.474.1718.1826.8937.2646.176.3813.8623.2833.5410.5416.925.4237.3817.5926.3937.953.6622.0234.2250.670.940.640.921.351.947.7923.9242.6656.110.9520.3128.2239.1518.9627.3133.0842.121.683.54.887.15
AURKAENSG00000087586333.016.2610.8221.48.9115.8722.7830.945.3110.0417.9627.914.6220.6527.4234.343.856.098.2212.0418.2525.8835.9146.9714.9418.8526.0234.9211.116.1625.3134.034.977.4311.1114.1110.8815.7721.7929.853.714.956.679.891.82.323.254.811.842.473.876.524.467.0411.0714.3711.472.565.693.816.7712.5619.944.599.3916.426.4712.3516.8223.3530.873.235.599.4715.198.9814.1120.9228.73.254.847.059.691.171.692.865.161.071.452.233.6618.1927.740.9450.74.9510.118.1725.29.2513.9920.6530.9211.3617.5826.7236.1616.0521.7529.7936.490.771.031.412.025.189.9915.7721.468.5113.2920.3427.5115.6120.6227.1133.071.7934.445.87
TTKENSG00000112742250.811.863.877.823.916.089.4213.992.143.717.1812.447.210.0113.3716.50.911.292.184.865.547.339.4312.373.374.746.929.325.988.5711.5615.992.153.55.58.554.376.539.8113.120.330.610.881.620.450.650.961.470.230.350.651.363.525.53810.810.250.521.192.830.431.062.334.731.142.514.878.355.788.5711.6615.31.092.193.615.574.677.211.0314.820.881.482.123.480.20.340.60.970.580.91.692.775.618.0911.2714.952.013.827.9811.191.93.025.157.793.686.389.8214.379.9114.420.1523.220.280.40.570.82.359.9522.6833.624.437.612.0216.267.4611.1413.3720.350.250.450.721.13
ESR1ENSG0000009183160.080.210.50.880.140.330.781.849.5753.22120.7212.090.681.95.6713.730.090.180.420.640.040.080.180.330.150.330.530.820.120.20.420.860.120.180.280.420.150.310.671.620.080.160.310.640.580.951.52.130.250.571.031.730.330.521.171.880.10.160.230.340.120.431.453.790.460.991.944.330.160.30.681.610.160.260.410.548.8715.3423.5935.620.20.340.681.10.120.210.320.50.881.542.764.20.040.080.150.340.270.631.47.990.150.30.530.80.140.270.540.840.150.210.350.480.831.663.268.950.180.290.751.289.731.6456.0888.720.480.721.86.980.240.511.111.82

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