Expression

 

Positive expression of a PDG in a given cancer type was defined as its mRNA expression was reliably detected in at least 50% of tumor specimens (i.e., the 50th percentile of fragments per kilobase of transcript per million mapped reads [FPKM] value ≥1).

 

Summary of PDG mRNA expression levels (FPKM value) in each cancer type


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HGNC Ensembl No. Detectable ACCBLCABRCACESCCHOLCOADDLBCESCAGBMHNSCKICHKIRCKIRPLAMLLGGLIHCLUADLUSCMESOOVPAADPCPGPRADREADSARCSKCMSTADTGCTTHCATHYMUCECUCSUVM
SymbolGene IDCancer Types25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th
FGFR1ENSG000000777823311.2523.9148.8572.322.455.6912.5125.3217.4227.9946.3876.912.395.3311.7531.7119.6330.1853.9370.953.767.3212.9121.435.5710.0116.6122.544.458.7315.6526.8522.4231.5544.362.783.497.0213.4523.3818.3129.1248.2963.0617.0224.1334.0142.9612.4823.7739.2854.482.896.3720.1844.7113.0418.883042.760.951.683.639.48.0213.1121.3635.969.5115.4427.3861.9239.2756.2874.41113.922.740.5566.0511720.627.9940.3852.4629.8849.6668.8989.8511.6217.6322.9731.584.417.3813.8118.395382.95126.43195.839.918.6136.7777.395.8610.9321.7539.9145.9381.54114.19165.047.2110.8216.322.96.9814.4431.5659.6820.5536.2171.3118.4346.1767.1995.06166.084.9810.4117.7524.15
IGF1RENSG00000140443311.813.685.758.572.614.346.4610.177.1815.825.8238.734.056.8610.0315.431.133.196.577.643.244.756.518.750.470.711.251.624.69.1916.123.371.973.054.626.846.389.9314.519.595.127.499.9111.375.758.4412.416.725.768.8712.1717.021.914.2710.9716.355.116.678.5611.290.120.220.471.463.425.568.5212.276.8910.9916.2522.233.145.6210.3216.363.797.1711.0916.83.95.337.198.655.549.3115.6823.938.3213.219.38263.625.367.018.352.033.67.4315.156.711.1917.6126.782.955.117.9511.474.526.749.3314.146.859.7112.5315.915.498.3314.1424.42.4358.912.254.325.978.3612.4511.1313.8717.2820.67
TYRP1ENSG00000107165200.010.050.370.030.130.531.170.030.10.331.3500.030.080.230.070.160.340.780.120.270.61000.030.120.180.551.323.160.020.070.160.390.030.10.320.8300.020.060.1300.020.060.2600.030.070.20000.080.020.070.170.4100.030.110.520.250.581.423.470.230.51.112.130.090.220.832.730.060.190.71.720.160.340.71.4200.030.080.170.070.160.350.690.160.320.81.370.010.050.251.870.4715.98397.281190.580.250.722.395.650.050.160.430.87000.020.040.010.421.7440.020.070.220.740.030.120.270.65983.61705.762486.623904.96
CDH1ENSG000000390682600.020.070.1764.73103.84148.82200.5550.5793.36148.34225.3565.6591.16119.01157.5483.31134.07190.2247.06108.28139.09171211.40.330.912.94.5968.62104.84145.71184.030.280.821.692.8558.8283.41109.11146.3646.7886.66110.59141.8311.5418.4427.4239.627.0215.331.2265.560.170.511.134.960.420.831.763.9116.8730.6249.5772.9361.3384.93121159.356.7382.9116.11158.96.1226.3649.1577.8128.0739.657.1275.8161.8285.81116.14142.730.010.020.070.2287.34117.96155.92188.77106.85145.01177.04212.860.070.231.0412.072.5125.5378.26132.6155.9589.66129.85161.468.3421.0550.3475.23118.28145.58180.07218.6223.4141.4873.19110.0246.4574.34103.3132.485.2718.7339.0168.9431.5875.26142.85172.82
TP53ENSG00000141510338.7512.9515.8422.0818.2128.7741.0555.8821.3230.7341.554.5426.2135.5246.6356.9425.6734.0846.6357.1431.0644.4857.0771.0230.8441.7151.6168.5511.8625.7841.158.8522.5331.3540.3749.1810.0321.0636.9554.445.877.969.7511.9715.9819.2622.8126.8217.6222.8328.4834.8431.4341.251.4659.615.0521.2227.7937.396.4110.1815.7322.5916.4624.1931.7741.711.4927.3942.6761.1826.0235.3343.6460.5513.5748.8368.9893.212.5117.7822.0225.785.958.1911.3714.1620.0424.6430.536.6520.0341.6959.3677.337.5718.2228.2541.521.0130.0839.7151.819.8433.4147.7268.8125.8832.1839.2950.8716.4219.4122.526.4831.5847.6557.9864.8831.4147.0663.7778.1525.8139.651.668.528.4133.0739.1446.32
GNASENSG0000008746033882.221205.151707.32538.77537.36698.2882.131108.35654.34835.041120.211598.3460.16575.57816.481144.14279.02429.53591.25648.47431.61555.81747.121017.6516.75586.75707.84827.48484.15615.66772.96947.68824.541027.161351.71822.58399.75497.27617.78766.331099.041319.321634.151899.63489.38609.63756.971023.93542.43662.69843.31045.83449.41548.86638.57758.29892.521005.991133.721266.77220.78308.32450.38658.98514.12649.64787.731098.31563.76742.84946.251196.56472.18596.67701.31891.01703.36924.11219.611510.79576.59708.49872.531187.773347.464873.917515.7510873.8528.3609.13728.86871.17499.59695.88880.511015.13592.16719.82965.461308.49668.46856.851125.931625.22434.23546.07733.53985.35262.53410.56633.33834.711301.691787.162638.954626.12728.31928.011098.181449.36772.51048.351372.981909.261354.461695.52307.953249.261333.461527.761907.342277.41
BCL2L1ENSG000001715523334.0748.666.990.9344.6361.3785.25119.3244.3155.2668.3882.7438.7251.1871.2799.36132.84193.38241.27313.956.9378.26110.58137.732.4444.6660.188.1730.3845.167.9997.6845.154.2565.5780.6338.3847.9560.7874.0982.95125.27156.65190.8563.3776.0389.61107.3693.85117.94157.69205.0815.1520.7430.946.1240.9848.8358.2869.130.8843.6362.8496.1550.0566.6493.86116.8141.8252.0968.7794.3436.6646.6657.1670.7754.2170.287.81108.3469.6489.45119.78150.0933.3139.0150.3863.1751.8959.6668.0777.8961.3387.75103.77135.7430.9939.4251.6569.4436.6646.8461.382.3543.8564.1793.02122.831.7439.9752.562.7148.9863.7894.5116.7653.3695.42143.96179.8943.0156.6771.0598.5942.6749.4479.1597.8249.4964.2480.63107.35
ATRENSG00000175054339.0411.5715.4220.556.548.4810.5213.126.037.468.8711.028.0310.213.5817.735.687.298.7512.995.146.688.5910.77.7710.5111.3112.58.0410.5913.9519.154.595.466.6584.586.088.7511.333.775.356.466.983.634.725.997.765.367.169.8612.2512.2616.1618.721.653.394.295.56.783.114.085.57.344.686.017.9310.215.758.0110.7614.786.047.239.0511.965.086.859.5812.465.16.37.549.253.134.445.987.545.266.287.628.895.657.488.9910.43.915.316.728.144.165.897.299.355.127.039.3412.213.745.166.628.34.585.46.487.988.5610.1211.713.667.158.9811.7515.176.288.5210.713.321.112.063.334.15
PPARGENSG00000132170291.72.714.396.8917.6663.53111.08151.822.093.516.5511.210.390.922.837.472.143.335.698.7123.3135.2649.3764.350.991.552.222.951.576.2517.7931.221.171.823.074.170.30.732.084.8113.6418.9727.8740.419.5512.7715.7820.313.116.7720.5525.860.130.522.3410.820.60.961.52.325.468.1414.1123.613.48.0913.5821.173.086.1110.5115.111.11.663.065.630.591.011.753.239.4416.0528.7348.431.52.313.925.451.151.873.36.6622.135.9250.5266.122.36.1113.2626.920.821.472.654.729.0814.552540.373.346.3910.9214.162.163.234.766.821.191.712.554.080.92.526.6115.211.743.316.1110.3313.119.2920.08
MMP1ENSG00000196611170.080.270.692.682.459.3746.12145.790.612.7211.8143.582.028.426.7684.820.2912.818.897.3422.9669.03174.851.243.715.23238.5313.9739.32117.32211.980.090.351.082.0742.16143.03391.9907.420.060.20.841.760.411.223.269.240.030.10.471.680000.0400.010.050.20.070.240.782.164.1713.542.73115.8213.5245.83133.84278.440.180.661.9614.180.250.682.558.4714.550.2593.87265.370.060.210.732.060.060.180.450.996.6322.9151.94154.180.231.044.8522.130.441.6510.1642.927.3227.8268.42162.510.170.582.1760.110.280.621.340.040.10.270.990.751.985.1319.211.284.047.4317.120.010.050.160.46
CDK2ENSG00000123374337.7314.1422.3130.4721.7531.8946.5163.31722.6429.5540.5537.351.3664.2978.4516.221.3926.7931.3222.0928.1432.7841.1516.3324.4839.2761.513.1516.6323.0628.6416.3122.2929.6635.8318.6625.0836.148.36.498.079.7912.2210.7613.6716.1519.399.3212.7116.7722.2321.6927.2932.6338.74.346.8710.419.035.568.8614.0322.8113.6618.4225.5836.6224.231.5540.852.2515.4819.5926.4832.518.525.7635.4647.2611.8114.9418.7622.963.14.155.566.811.4214.1617.1620.1519.8126.6731.4837.3815.5224.9938.4860.6155.13139.05328.06517.5212.116.5223.1732.1121.629.1342.4551.228.5110.9413.3515.1713.7222.0333.5943.513.9422.0533.1142.4318.2427.8738.1551.28138.93225.17320.19432.57
THENSG000001801761000.060.310.140.884.4717.030.010.080.30.90.050.230.932.5600.030.10.250.160.440.951.740000.020.040.110.371.10.020.060.150.280.070.280.973000.020.06000.020.070.010.060.170.3800000.030.090.160.31000.040.1400.060.170.520.010.050.180.490.060.220.581.950.040.120.310.650.070.180.411.4898.171413.762051.092811.5500.020.080.160.350.721.412.2900.040.190.7300.020.090.250.030.10.280.780.090.20.41.410.060.150.280.610.020.070.160.290.030.130.371.010.180.421.043.090.050.090.240.58
BUB1ENSG00000169679270.852.274.049.575.899.6514.5419.153.336.0810.7216.498.0411.2414.6118.442.163.045.076.468.911.9915.5919.4911.6116.2722.4431.127.7512.5717.1222.994.086.339.0412.455.648.9512.6616.120.440.831.462.50.81.262.053.350.40.671.242.769.5914.419.9126.260.490.991.994.850.661.633.265.652.685.419.5115.267.6811.2614.9518.571.893.456.028.336.179.5314.1819.991.932.864.325.870.310.561.121.850.470.81.472.627.841115.7518.843.357.3613.1119.984.998.3212.4716.936.710.6915.9221.3113.5119.9426.831.670.450.831.42.083.7511.0120.2125.736.8310.917.5522.349.9912.7616.3420.270.751.572.373.42
GALENSG0000006948214000.080.460.070.382.7110.970.320.82.418.720.070.341.938.760.040.271.061.681.986.1317.334.160.030.090.240.510.372.2110.9424.220.531.473.5711.040.230.823.6412.6100.020.10.2600.020.080.20.040.130.491.640.040.090.240.820.090.280.71.3900.030.090.610.140.441.9590.772.326.9218.110.30.782.025.20.51.33.4910.30.581.323.115.090.371.9721.5896.111.593.175.7710.673.98.5517.5530.470.050.291.544.640.120.431.797.810.322.8113.6333.350.432.9458.17131.720.020.050.110.250.030.070.281.010.371.132.9610.111.925.8111.5316.482.936.6811.6716.71
ERBB3ENSG00000065361270.190.350.531.0622.5845.2977.25112.2156.8986.29121.61159.9227.1937.5356.1185.1571.58110.71153.67191.6865.6581.61101.97129.620.060.10.230.5120.3142.4782.06114.291.84.229.518.5811.5716.5223.2533.944.810.0615.1619.4227.724667.188.129.7249.9588.55115.280.040.130.250.494.888.9516.9127.7334.6950.2368.4394.2536.5557.2284.31114.5112.1218.8527.6940.590.772.546.2612.4119.2331.5945.8867.7830.3747.6178.1599.270.170.93.157.8757.8470.4987.75103.9564.582105.31128.530.110.240.642.3368.69112.85174.69226.7246.8767.2794.21125.4911.718.1327.5541.048.3322.3829.6836.680.130.521.828.4228.2837.8245.9173.379.1228.2440.0259.1623.3244.2563.56108.01
MDM2ENSG000001356793339.7555.4582.7114.2932.1947.879.57177.7528.3136.851.3376.239.3752.7268.94106.4428.1940.0846.0770.6914.9919.830.7942.0538.460.6285.84117.8424.0329.6140.857.8925.6235.8647.0577.3618.6725.537.0657.8712.5217.0822.2626.931.6541.9556.1277.1131.3446.0666.2191.837.2546.3158.8779.9118.4422.7929.5539.9424.232.6749.272.6522.7330.1643.5969.7823.5529.8738.7553.1934.342.753.8267.9212.2516.4622.1130.6518.5923.8630.1642.2215.0620.4330.339.3425.8132.1340.6751.4714.5717.1721.831.7217.6125.1854.09677.3221.6637.8356.687.0722.8232.348.2378.2244.7265.7296.08136.7832.0242.3655.1378.241.8454.6472.1593.7932.0850.5373.92118.6325.0934.9448.0570.3119.0832.5252.3774.21
TNFSF10ENSG00000121858326.8411.0118.737.1319.2445.48102.65229.6941.2675.58137.56226.7472.14152.77309.21548.3236.6365.188.26127.2223.7432.7543.7457.7316.6526.4840.3668.0728.6549.4287.08169.284.137.2311.8417.0661.15113.29198.72292.696.3410.315.7724.8278.12120.87178.12261.783.19178.37297.86442.188.8816.7832.0758.141.843.075.458.9420.1136.0961.55100.3730.3954.190.15138.3661.85103.51197.83319.548.2316.3928.958.9624.6150.1796.16182.5329.6640.5656.473.73.015.218.1712.2170.09100.04136.74186.6124.1232.4844.3759.327.9619.1237.6866.112.736.1915.1431.5722.5334.656.6387.077.113.0824.1841.086.869.5414.0620.615.537.9512.4122.7121.8942.9793.28170.043.5910.0726.6343.060.250.571.362.58
AKT1ENSG000001422083336.3460.1578.79111.3853.3866.0979.8796.960.4278.95101.8132.8448.9463.278.6893.4934.2641.2458.4367.3151.8264.4975.0385.6828.3941.4663.3868.2647.2561.7875.9889.849.9470.7787.17104.6452.0965.681.8398.7168.3384.16102.98120.7337.5547.7956.5264.5539.1849.0557.165.5549.1864.4980.2193.5346.9456.0365.6874.9825.7733.1344.8955.5354.0468.4783.36103.0657.6371.7591.96114.1739.0747.0158.4667.6250.8171.6195.8119.4955.3163.6871.9581.652.5867.8982.3395.183.2297.24111.82128.7146.2256.4267.878.1156.1674.4995.79119.6267.4986.96116.31149.0847.0560.5774.7486.7836.4743.6556.3479.5257.2766.0773.6986.845.4154.2361.271.8658.873.6691.57113.3157.669.9985.71111.8881.2493.03109.43142.1
PTENENSG000001718623313.4216.6624.253115.1920.4126.5933.8518.4226.1835.0944.4615.1419.9624.7531.0214.8317.492127.3718.0621.6426.6231.2720.1327.634.6945.7923.8431.0238.9146.258.9312.4615.520.8818.3124.0630.1537.138.2510.914.0817.2319.224.430.2236.2410.3813.4917.4321.5564.6782.27105.88124.510.1912.2214.5716.8712.2415.7420.5526.0516.0320.0625.433.9214.3719.6427.235.2616.2919.8524.0328.9915.2421.7929.4237.9919.7325.5231.0738.0115.919.3823.5227.7113.6118.0122.6428.2217.7421.2426.2429.6113.6317.5622.4229.6913.1418.7526.8737.2422.8430.9339.9750.6614.9717.6821.625.9814.2616.5819.822.5221.6429.2436.4841.8312.819.324.9635.0816.2419.8323.5633.3624.4531.4844.5254.76
COL1A2ENSG000001646923214.5130.3160.19133.8172.02237.73656.441309.5438.98888.731561.72463.8447.18100.89222.72468.84120171.34294.43393.07121.08275.28512.41938.6753.79118.77225.72383.36118.21241.38600.781228.7428.2851.15109.86293.04127.75299.45720.741559.2110.1717.7632.5896.0562.03120.43251.8447111.8728.2763.47134.990.110.681.974.263.555.7513.2929.9510.7727.9765.66147.77155.65285.65513.35877.87153.4315.34635.651165.12440.81833.251540.873415.25154.35318.64765.481345.16551.43941.421468.912250.0332.2252.2388.67191.8458.5795.23151.08250.5139.99278.98471938.65697.91456.543052.025739.0879.35158.57376.13764.39161.18311.61629.231065.76111.99233.82689.212145.6733.8168.71149.76324.29.2127.6793.11268.8767.13140.81253.7451.44353.9508.961088.332190.8319.4739.288.72218.45

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