TP53
Official symbol: | TP53 |
Full name: | tumor protein p53 |
Location: | |
Also known as: | LFS1, p53 |
Entrez ID: | 7157 |
Ensembl ID: | ENSG00000141510 |
Summary: | |
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Overall distribution
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Tissue specific distribution
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Overall distribution
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Tissue specific distribution
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Gscore (Amp): | 0.00 | Gscore (Del): | 1.12 (Driver) |
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Recurrently deleted in 3 cancer type(s) |
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Overall distribution
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Tissue specific distribution
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Recurrently mutated in 24 cancer type(s) |
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Overall
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Tissue specific
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Total fusion occurrence: | 7 |
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Fusions detected in 5 cancer type(s) |
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Functional class: | Transcription factor |
JensenLab PubMed score: | 54026.30 (Percentile rank: 99.99%) |
PubTator score: | 35081.83 (Percentile rank: 99.99%) |
Target development/druggability level: | TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below. |
Tractability (small molecule): | Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands |
Tractability (antibody): | |