Transcript Fusion
The transcript fusion data of TCGA were retrieved from the TumorFusions database.
List of the transcript fusions of the CDKs/cyclins in each cancer type
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Cancer Type | TCGA_barcode | Patient | Fusion_transcript | Gene_A | Gene_B | Chr_A | Chr_B | Strand_A | Strand_B | #_Discordant_Pairs | #_JSR | #_perfect_JSR | Evalue | Junction_A | Junction_B | Tier | Frame | TN | WGS_validation | Centrality |
BRCA | TCGA-E2-A14V-01A | TCGA-E2-A14V | SYNCRIP|CDK19 | SYNCRIP | CDK19 | 6 | 6 | -1 | -1 | 129 | 82 | 78 | 0.41 | 86352515 | 111067404 | tier1 | 5UTR-CDS | 17238 | NA | 0 |
BRCA | TCGA-E9-A248-01A | TCGA-E9-A248 | SYNJ2|CDK19 | SYNJ2 | CDK19 | 6 | 6 | 1 | -1 | 3 | 7 | 6 | 1.6 | 158487667 | 111067404 | tier1 | Out-of-frame | 17254 | NA | 0 |
SARC | TCGA-3B-A9HL-01A | TCGA-3B-A9HL | FYN|CDK19 | FYN | CDK19 | 6 | 6 | -1 | -1 | 43 | 44 | 43 | 0.23 | 112194171 | 110953364 | tier1 | 5UTR-CDS | 6852 | NA | 0.38625 |
SARC | TCGA-DX-A1L4-01A | TCGA-DX-A1L4 | TBK1|CDK19 | TBK1 | CDK19 | 12 | 6 | 1 | -1 | 26 | 17 | 15 | 0.017 | 64879293 | 110935869 | tier1 | In-frame | 17535 | NA | 0 |
UVM | TCGA-VD-A8KJ-01A | TCGA-VD-A8KJ | FYN|CDK19 | FYN | CDK19 | 6 | 6 | -1 | -1 | 6 | 17 | 17 | 0.23 | 112101769 | 110935869 | tier1 | 5UTR-CDS | 6853 | NA | 0.38625 |
BRCA | TCGA-AR-A0TP-01A | TCGA-AR-A0TP | PDPK1|CCNF | PDPK1 | CCNF | 16 | 16 | 1 | 1 | 8 | 1 | 1 | 0.33 | 2588137 | 2495459 | tier2 | Out-of-frame | 12562 | NA | 0.38668 |
BLCA | TCGA-G2-AA3B-01A | TCGA-G2-AA3B | RAPGEFL1|CDK12 | RAPGEFL1 | CDK12 | 17 | 17 | 1 | 1 | 2 | 2 | 2 | 0.027 | 38334633 | 37686884 | tier2 | In-frame | 14303 | NA | 0 |
BRCA | TCGA-3C-AALI-01A | TCGA-3C-AALI | ARSG|CDK12 | ARSG | CDK12 | 17 | 17 | 1 | 1 | 2 | 6 | 6 | 0.3 | 66352945 | 37667782 | tier3 | In-frame | 1465 | NA | 0.32575 |
BRCA | TCGA-BH-A204-01A | TCGA-BH-A204 | ERBB2|CDK12 | ERBB2 | CDK12 | 17 | 17 | 1 | 1 | 175 | 94 | 75 | 0.41 | 37868701 | 37680927 | tier1 | In-frame | 5717 | NA | 0.38259 |
BRCA | TCGA-AR-A250-01A | TCGA-AR-A250 | PDK2|CDK12 | PDK2 | CDK12 | 17 | 17 | 1 | 1 | 24 | 26 | 24 | 1 | 48182806 | 37627132 | tier1 | In-frame | 12548 | NA | 0.36144 |
BRCA | TCGA-A2-A04W-01A | TCGA-A2-A04W | RARA|CDK12 | RARA | CDK12 | 17 | 17 | 1 | 1 | 19 | 18 | 17 | 0.28 | 38474700 | 37646810 | tier1 | 5UTR-CDS | 14309 | NA | 0 |
BRCA | TCGA-A1-A0SN-01A | TCGA-A1-A0SN | TUBD1|CDK12 | TUBD1 | CDK12 | 17 | 17 | -1 | 1 | 117 | 47 | 46 | 0.73 | 57943970 | 37667782 | tier2 | Out-of-frame | 18932 | NA | 0 |
LUAD | TCGA-95-7947-01A | TCGA-95-7947 | MED1|CDK12 | MED1 | CDK12 | 17 | 17 | -1 | 1 | 167 | 261 | 215 | 1.7 | 37607291 | 37627132 | tier1 | Out-of-frame | 10150 | NA | 0.35216 |
OV | TCGA-3P-A9WA-01A | TCGA-3P-A9WA | RARA|CDK12 | RARA | CDK12 | 17 | 17 | 1 | 1 | 5 | 89 | 76 | 0.28 | 38504716 | 37686857 | tier1 | Out-of-frame | 14308 | NA | 0 |
PCPG | TCGA-SR-A6MP-01A | TCGA-SR-A6MP | USP33|CDK12 | USP33 | CDK12 | 1 | 17 | -1 | 1 | 5 | 2 | 2 | 1.3 | 78225328 | 37627132 | tier1 | 5UTR-CDS | 19356 | NA | 0 |
PRAD | TCGA-YJ-A8SW-01A | TCGA-YJ-A8SW | NSRP1|CDK12 | NSRP1 | CDK12 | 17 | 17 | 1 | 1 | 17 | 15 | 14 | 0.21 | 28445191 | 37646810 | tier1 | Out-of-frame | 11808 | NA | 0 |
STAD | TCGA-BR-4366-01A | TCGA-BR-4366 | CASC3|CDK12 | CASC3 | CDK12 | 17 | 17 | 1 | 1 | 10 | 10 | 9 | 0.12 | 38297860 | 37686884 | tier1 | Out-of-frame | 3003 | NA | 0.34002 |
STAD | TCGA-CG-4449-01A | TCGA-CG-4449 | GRB7|CDK12 | GRB7 | CDK12 | 17 | 17 | 1 | 1 | 20 | 11 | 11 | 0.054 | 37902455 | 37680927 | tier1 | Out-of-frame | 7414 | NA | 0.37831 |
STAD | TCGA-BR-8289-01A | TCGA-BR-8289 | THRA|CDK12 | THRA | CDK12 | 17 | 17 | 1 | 1 | 2 | 30 | 26 | 0.41 | 38245586 | 37686884 | tier2 | Out-of-frame | 17777 | NA | 0 |
UCEC | TCGA-KP-A3W4-01A | TCGA-KP-A3W4 | TMLHE|CDK12 | TMLHE | CDK12 | X | 17 | -1 | 1 | 2 | 1 | 1 | 0.83 | 154842453 | 37646810 | tier2 | 5UTR-CDS | 18073 | NA | 0 |
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