Transcript Fusion
The transcript fusion data of TCGA were retrieved from the TumorFusions database.
List of the transcript fusions of the CDKs/cyclins in each cancer type
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Cancer Type | TCGA_barcode | Patient | Fusion_transcript | Gene_A | Gene_B | Chr_A | Chr_B | Strand_A | Strand_B | #_Discordant_Pairs | #_JSR | #_perfect_JSR | Evalue | Junction_A | Junction_B | Tier | Frame | TN | WGS_validation | Centrality |
LUAD | TCGA-44-7670-01A | TCGA-44-7670 | FAM133B|CDK6 | FAM133B | CDK6 | 7 | 7 | -1 | -1 | 2 | 6 | 6 | 1 | 92219582 | 92463004 | tier2 | CDS-5UTR | 6044 | NA | 0.38362 |
THCA | TCGA-EM-A3AQ-01A | TCGA-EM-A3AQ | WARS|CCNY | WARS | CCNY | 14 | 10 | -1 | 1 | 13 | 8 | 8 | 0.44 | 100828045 | 35772332 | tier1 | CDS-5UTR | 19706 | validated | 0 |
HNSC | TCGA-DQ-7589-01A | TCGA-DQ-7589 | ORAOV1|CCND1 | ORAOV1 | CCND1 | 11 | 11 | -1 | 1 | 30 | 19 | 18 | 0.38 | 69489958 | 69457799 | tier1 | Out-of-frame | 12045 | NA | 0.36906 |
BRCA | TCGA-OL-A5RZ-01A | TCGA-OL-A5RZ | TBC1D22B|CCND3 | TBC1D22B | CCND3 | 6 | 6 | 1 | -1 | 13 | 5 | 5 | 1 | 37254848 | 41908323 | tier1 | In-frame | 17481 | NA | 0 |
PRAD | TCGA-G9-6353-01A | TCGA-G9-6353 | GMDS|CCND3 | GMDS | CCND3 | 6 | 6 | -1 | -1 | 8 | 8 | 6 | 0.012 | 2245555 | 41905132 | tier1 | In-frame | 7141 | NA | 0.37344 |
STAD | TCGA-VQ-A925-01A | TCGA-VQ-A925 | SRPK1|CCND3 | SRPK1 | CCND3 | 6 | 6 | -1 | -1 | 17 | 65 | 59 | 1.4 | 35888245 | 41908323 | tier1 | Out-of-frame | 16867 | NA | 0 |
UCS | TCGA-NA-A4QV-01A | TCGA-NA-A4QV | MED20|CCND3 | MED20 | CCND3 | 6 | 6 | -1 | -1 | 13 | 5 | 5 | 2.5 | 41884523 | 41908323 | tier1 | Out-of-frame | 10205 | NA | 0.36789 |
LUSC | TCGA-22-1017-01A | TCGA-22-1017 | GCN1L1|CCND2 | GCN1L1 | CCND2 | 12 | 12 | -1 | 1 | 10 | 8 | 8 | 0.16 | 120600651 | 4398008 | tier1 | Out-of-frame | 7011 | NA | 0.36965 |
BLCA | TCGA-DK-AA6P-01A | TCGA-DK-AA6P | UBL3|CDK8 | UBL3 | CDK8 | 13 | 13 | -1 | 1 | 2 | 4 | 4 | 0.48 | 30423649 | 26911704 | tier3 | Out-of-frame | 19120 | NA | 0 |
PRAD | TCGA-ZG-A9KY-01A | TCGA-ZG-A9KY | WASF3|CDK8 | WASF3 | CDK8 | 13 | 13 | 1 | 1 | 3 | 2 | 2 | 0.52 | 27257111 | 26911704 | tier2 | Out-of-frame | 19738 | NA | 0 |
PRAD | TCGA-J4-AATZ-01A | TCGA-J4-AATZ | SMAD9|CCNA1 | SMAD9 | CCNA1 | 13 | 13 | -1 | 1 | 14 | 13 | 12 | 0.39 | 37427556 | 37007170 | tier1 | In-frame | 16355 | NA | 0 |
BLCA | TCGA-2F-A9KP-01A | TCGA-2F-A9KP | OCLN|CCNB1 | OCLN | CCNB1 | 5 | 5 | 1 | 1 | 16 | 21 | 19 | 0.5 | 68809936 | 68467097 | tier1 | In-frame | 12000 | NA | 0.37707 |
LIHC | TCGA-BC-A3KG-01A | TCGA-BC-A3KG | FAM160A1|CCNA2 | FAM160A1 | CCNA2 | 4 | 4 | 1 | -1 | 25 | 16 | 10 | 0.46 | 152403800 | 122742246 | tier1 | 5UTR-CDS | 6066 | NA | 0.37031 |
LIHC | TCGA-CC-5263-01A | TCGA-CC-5263 | KIAA1109|CCNA2 | KIAA1109 | CCNA2 | 4 | 4 | 1 | -1 | 39 | 20 | 12 | 0.45 | 123075267 | 122742246 | tier1 | 5UTR-CDS | 8821 | NA | 0.36776 |
LIHC | TCGA-DD-A1EK-01A | TCGA-DD-A1EK | KIAA1109|CCNA2 | KIAA1109 | CCNA2 | 4 | 4 | 1 | -1 | 11 | 9 | 6 | 0.45 | 123075267 | 122742246 | tier1 | 5UTR-CDS | 8822 | NA | 0.36776 |
LIHC | TCGA-PD-A5DF-01A | TCGA-PD-A5DF | KIAA1109|CCNA2 | KIAA1109 | CCNA2 | 4 | 4 | 1 | -1 | 13 | 18 | 18 | 0.45 | 123075267 | 122742246 | tier1 | 5UTR-CDS | 8823 | non-validated | 0.36776 |
LIHC | TCGA-GJ-A6C0-01A | TCGA-GJ-A6C0 | LIPC|CCNA2 | LIPC | CCNA2 | 15 | 4 | 1 | -1 | 10 | 6 | 5 | 3.6 | 58703017 | 122742246 | tier1 | 5UTR-CDS | 9365 | NA | 0.36979 |
LIHC | TCGA-DD-A3A5-01A | TCGA-DD-A3A5 | UBA6|CCNA2 | UBA6 | CCNA2 | 4 | 4 | -1 | -1 | 2 | 5 | 5 | 2.2 | 68566767 | 122742246 | tier2 | Out-of-frame | 19028 | NA | 0 |
STAD | TCGA-BR-8687-01A | TCGA-BR-8687 | AL139022.1|CCNA2 | AL139022.1 | CCNA2 | 14 | 4 | 1 | -1 | 2 | 3 | 3 | 0.98 | 65453815 | 122743801 | tier3 | In-frame | 773 | NA | 0.36415 |
PRAD | TCGA-HC-A8D1-01A | TCGA-HC-A8D1 | SKIV2L2|CCNO | SKIV2L2 | CCNO | 5 | 5 | 1 | -1 | 2 | 1 | 1 | 0.74 | 54623606 | 54528374 | tier3 | In-frame | 15991 | NA | 0 |
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