Mutation

 

The putative cancer-causing CDKs and cyclins driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing CDKs/cyclins driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
CCNF  ENSG00000162063                                                                                                                                      
CCNG1  ENSG00000113328                                                                                                                                      
CCNG2  ENSG00000138764                                                                                                                                      
CCNI  ENSG00000118816                                                                                                                                      
CCNI2  ENSG00000205089                                                                                                                                      
CCNJ  ENSG00000107443                                                                                                                                      
CCNO  ENSG00000152669                                                                                                                                      

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