Copy Number

 

The putative cancer-causing CDKs/Cyclins driven by SCNAs in each cancer type were identified by four criteria: 1) located in a peak region of a significantly recurrent focal SNCA locus estimated by the genomic identification of significant targets in cancer (GISTIC2) algorithm, (q≤0.25); 2) altered with high frequency and large amplitude (G-score ≥0.1); 3) mRNA reliably detected in at least 10% of tumor specimens in the given cancer type (90th percentile of FPKM value ≥1); and 4) mRNA significantly and positively correlated with copy numbers (Pearson P-value less than 0.001).

 

List of the putative cancer-causing CDKs/cyclins driven by SCNAs in each cancer type


 Show   entries each page
 Jump to page  

 Total Page: 3 Total entries: 47
 
 Showing page 3  first page | previous page | next page | last page 
 
HGNC Ensembl ACCBLCABRCACESCCHOLCOADDLBCESCAGBMHNSCKICHKIRCKIRPLAMLLGGLIHCLUADLUSCMESOOVPAADPCPGPRADREADSARCSKCMSTADTGCTTHCATHYMUCECUCSUVM
 Symbol  Gene ID  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del  Amp  Del 
CCNF  ENSG00000162063                                                                                                                                                                                                                                                                          
CCNG1  ENSG00000113328                1                                                                            1                                                                                                                    1                                                          
CCNG2  ENSG00000138764                                                                                                                                                                                                                                                                          
CCNI  ENSG00000118816                                                                                                                                                                                                                                                                          
CCNI2  ENSG00000205089                                                                                                                                                                                                                                                                          
CCNJ  ENSG00000107443                                                                                                                                                        1        1                                                                                                          
CCNO  ENSG00000152669                                                                                                                                                                                                                                                                          

 Showing page 3 
first page | previous page | next page | last page 








Contact us | | Terms & Conditions.
Copyright © 2015 University of Pennsylvania. All Rights Reserved.