Cancer Type

 

By integrating multi-dimensional genomic profiles, we comprehensively analyzed the recurrent genomic alterations of the genes encoding CDKs/cyclins in the Cancer Genome Atlas cohort (n>11,000, with samples of 33 cancer types from 27 primary sites) for copy number alterations, mutations, and transcript fusions.

 

Summary of TCGA specimens



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          RNA-seq          
 Abbreviations  Primary Site  Cancer Type  Normal  Tumor  SNP Array  Exome-seq  Transcript fusion 
PAAD  Pancreas    Pancreatic adenocarcinoma    4    177    184    177    178  
PCPG  Adrenal Gland    Pheochromocytoma and Paraganglioma    3    178    162    179    179  
PRAD  Prostate    Prostate adenocarcinoma    52    495    492    497    497  
READ  Rectal    Rectum adenocarcinoma    10    166    165    150    94  
SARC  Soft Tissue    Sarcoma    2    259    257    236    259  
SKCM  Skin    Skin Cutaneous Melanoma    1    468    469    466    469  
STAD  Stomach    Stomach adenocarcinoma    32    375    441    439    414  
TGCT  Testis    Testicular Germ Cell Tumors    0    150    150    145    150  
THYM  Thymus    Thymoma    2    119    123    123    120  
THCA  Thyroid    Thyroid carcinoma    58    502    499    492    505  
UCS  Uterine    Uterine Carcinosarcoma    0    56    56    57    57  
UCEC  Uterine    Uterine Corpus Endometrial Carcinoma    35    543    539    530    180  
UVM  Eye    Uveal Melanoma    0    80    80    80    80  
Total          730    10201    10950    10224    9799  

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