Cancer Type
By integrating multi-dimensional genomic profiles, we comprehensively analyzed the recurrent genomic alterations of the genes encoding CDKs/cyclins in the Cancer Genome Atlas cohort (n>11,000, with samples of 33 cancer types from 27 primary sites) for copy number alterations, mutations, and transcript fusions.
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RNA-seq | |||||||
Abbreviations | Primary Site | Cancer Type | Normal | Tumor | SNP Array | Exome-seq | Transcript fusion |
PAAD | Pancreas | Pancreatic adenocarcinoma | 4 | 177 | 184 | 177 | 178 |
PCPG | Adrenal Gland | Pheochromocytoma and Paraganglioma | 3 | 178 | 162 | 179 | 179 |
PRAD | Prostate | Prostate adenocarcinoma | 52 | 495 | 492 | 497 | 497 |
READ | Rectal | Rectum adenocarcinoma | 10 | 166 | 165 | 150 | 94 |
SARC | Soft Tissue | Sarcoma | 2 | 259 | 257 | 236 | 259 |
SKCM | Skin | Skin Cutaneous Melanoma | 1 | 468 | 469 | 466 | 469 |
STAD | Stomach | Stomach adenocarcinoma | 32 | 375 | 441 | 439 | 414 |
TGCT | Testis | Testicular Germ Cell Tumors | 0 | 150 | 150 | 145 | 150 |
THYM | Thymus | Thymoma | 2 | 119 | 123 | 123 | 120 |
THCA | Thyroid | Thyroid carcinoma | 58 | 502 | 499 | 492 | 505 |
UCS | Uterine | Uterine Carcinosarcoma | 0 | 56 | 56 | 57 | 57 |
UCEC | Uterine | Uterine Corpus Endometrial Carcinoma | 35 | 543 | 539 | 530 | 180 |
UVM | Eye | Uveal Melanoma | 0 | 80 | 80 | 80 | 80 |
Total | 730 | 10201 | 10950 | 10224 | 9799 |
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