Mutation

 

The putative cancer-causing GESPs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

Summary of mutation frequency of the recurrent mutated GESPs in each cancer type


 Show   entries each page
 Jump to page  

 
 Showing page 1  first page | previous page | next page | last page 
 
 HGNC Name  Ensembl Gene ID  HGNC Symbol  Genomic Location  ACC_Mut%  BLCA_Mut%  BRCA_Mut%  CESC_Mut%  CHOL_Mut%  COAD_Mut%  DLBC_Mut%  ESCA_Mut%  GBM_Mut%  HNSC_Mut%  KICH_Mut%  KIRC_Mut%  KIRP_Mut%  LAML_Mut%  LGG_Mut%  LIHC_Mut%  LUAD_Mut%  LUSC_Mut%  MESO_Mut%  OV_Mut%  PAAD_Mut%  PCPG_Mut%  PRAD_Mut%  READ_Mut%  SARC_Mut%  SKCM_Mut%  STAD_Mut%  TGCT_Mut%  THCA_Mut%  THYM_Mut%  UCEC_Mut%  UCS_Mut%  UVM_Mut% 
catenin beta 1ENSG00000168036CTNNB1chr3:41194837-41260096:+  15.56    3.05                3.87        3.31                                25.83    3.2                        2.04            4.74    4.34                22.17          
erb-b2 receptor tyrosine kinase 2ENSG00000141736ERBB2chr17:39687914-39730426:+      11.2    2.48    4.01                4.42                                    1.69                                        3.25                          
eukaryotic translation elongation factor 1 alpha 1ENSG00000156508EEF1A1chr6:73515750-73523797:-      2.29                1.61            1.55    1.59                        2.78                                                                      
epidermal growth factor receptorENSG00000146648EGFRchr7:55019021-55256620:+                                  23.2                        6.67        12.43    1.93                                                              
major histocompatibility complex, class I, BENSG00000234745HLA-Bchr6:31353872-31357188:-              3.28                        3.78                                                                    2.17                1.11          
activin A receptor type 2AENSG00000121989ACVR2Achr2:147844517-147930826:+                      3.87                                        2.78                                            4.61                6.87          
erb-b2 receptor tyrosine kinase 3ENSG00000065361ERBB3chr12:56079857-56103505:+      9.92                                                                                                    4.61                5.32          
interleukin 7 receptorENSG00000168685IL7Rchr5:35852695-35879603:+                                                                  2.82    4.72                                    1.9                          
fibroblast growth factor receptor 2ENSG00000066468FGFR2chr10:121478334-121598458:-          1.24                                                            2.79                                                    10.86          
fibroblast growth factor receptor 3ENSG00000068078FGFR3chr4:1793307-1808872:+      13.99                                1.79                                1.93                                                              
myosin heavy chain 9ENSG00000100345MYH9chr22:36281281-36388018:-          2.38                            4.18                                                                    3.25                          
ring finger protein 43ENSG00000108375RNF43chr17:58352500-58417595:-                                                                                  5.75                        3.25                11.31          
neurofibromin 2ENSG00000186575NF2chr22:29603556-29698598:+                                                  3.2                0.94        22.22                                                          
microtubule actin crosslinking factor 1ENSG00000127603MACF1chr1:39081316-39487177:+      12.72                                5.38                                                                7.58                              
heat shock protein 90 alpha family class B member 1ENSG00000096384HSP90AB1chr6:44246166-44253888:+                                                                  1.32    1.29                                    1.63                          
beta-2-microglobulinENSG00000166710B2Mchr15:44711477-44718877:+              1.46            24.32                                                                            1.66                              
ras homolog family member AENSG00000067560RHOAchr3:49359145-49412998:-      4.83                                1.79                                                                    5.69                          
Rac family small GTPase 1ENSG00000136238RAC1chr7:6374523-6403977:+                                      2.59                                0.86                                4.5                              
cadherin 1ENSG00000039068CDH1chr16:68737225-68835548:+          12.19                                                                                                8.67                          
transforming growth factor beta receptor 2ENSG00000163513TGFBR2chr3:30606502-30694142:+                                      4.58                                            4.02                                                  

 Showing page 1  		first page | previous page | next page | last page 








Contact us | | Terms & Conditions.
Copyright © 2020 University of Pennsylvania. All Rights Reserved.