GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
fms related receptor tyrosine kinase 3ENSG00000122025FLT3chr13:28003274-28100592:-1114.5
CD276 moleculeENSG00000103855CD276chr15:73683966-73714518:+1117.5
cholinergic receptor nicotinic alpha 3 subunitENSG00000080644CHRNA3chr15:78593052-78621295:-1112.5
solute carrier organic anion transporter family member 3A1ENSG00000176463SLCO3A1chr15:91853695-92172435:+1114.5
post-glycosylphosphatidylinositol attachment to proteins 6ENSG00000129925TMEM8Achr16:370773-387113:-1114.5
adenylate cyclase 9ENSG00000162104ADCY9chr16:3953387-4116185:-1116.5
integrin subunit alpha XENSG00000140678ITGAXchr16:31355134-31382997:+1013.5
integrin subunit alpha 2bENSG00000005961ITGA2Bchr17:44372180-44389505:-1011.5
intercellular adhesion molecule 2ENSG00000108622ICAM2chr17:64002594-64020634:-1116.5
rhomboid 5 homolog 2ENSG00000129667RHBDF2chr17:76470891-76501790:-1117.5
CD7 moleculeENSG00000173762CD7chr17:82314868-82317602:-1011.5
CD70 moleculeENSG00000125726CD70chr19:6583183-6604103:-1117.5
Fc fragment of IgE receptor IIENSG00000104921FCER2chr19:7688758-7702146:-1012.5
mucin 16, cell surface associatedENSG00000181143MUC16chr19:8848844-8981342:-1013.5
intercellular adhesion molecule 3ENSG00000076662ICAM3chr19:10333776-10339823:-1014.5
basal cell adhesion molecule (Lutheran blood group)ENSG00000187244BCAMchr19:44809059-44821420:+1016.5
sialic acid binding Ig like lectin 7ENSG00000168995SIGLEC7chr19:51142299-51153526:+1014.5
calcium voltage-gated channel auxiliary subunit gamma 6ENSG00000130433CACNG6chr19:53992288-54012669:+1011.5
adenylate cyclase 3ENSG00000138031ADCY3chr2:24819169-24919839:-1116.5
solute carrier family 8 member A1ENSG00000183023SLC8A1chr2:40097270-40611053:-1013.5

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