GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
olfactory receptor family 2 subfamily T member 7ENSG00000227152OR2T7chr1:248441207-248442133:+44.5
TUB like protein 3ENSG00000078246TULP3chr12:2877223-2941140:+56.5
plakophilin 2ENSG00000057294PKP2chr12:32790745-32896840:-58
mitogen-activated protein kinase kinase kinase 12ENSG00000139625MAP3K12chr12:53479669-53500063:-44.5
ankyrin repeat and sterile alpha motif domain containing 1BENSG00000185046ANKS1Bchr12:98726457-99984654:-44
ADP ribosylation factor 6ENSG00000165527ARF6chr14:49893092-49897054:+49
CASP8 and FADD like apoptosis regulatorENSG00000003402CFLARchr2:201116104-201176687:+55
myosin XENSG00000145555MYO10chr5:16661914-16936276:-44
neuropeptide Y receptor Y6 (pseudogene)ENSG00000226306NPY6Rchr5:137801193-137810751:+44.5
cyclase associated actin cytoskeleton regulatory protein 2ENSG00000112186CAP2chr6:17393216-17557792:+47
TRPM8 channel associated factor 2ENSG00000170379TCAF2chr7:143620950-143730409:+55
cyclin dependent kinase 5ENSG00000164885CDK5chr7:151053812-151058530:-46
regulating synaptic membrane exocytosis 2ENSG00000176406RIMS2chr8:103500748-104256094:+55.5
protein phosphatase 1 regulatory subunit 16AENSG00000160972PPP1R16Achr8:144477969-144502121:+45
tight junction protein 2ENSG00000119139TJP2chr9:69121264-69255208:+57.5
regulator of solute carriers 1ENSG00000215695RSC1A1chr1:15659869-15661722:+44
RAB3B, member RAS oncogene familyENSG00000169213RAB3Bchr1:51907956-51990764:-59
DnaJ heat shock protein family (Hsp40) member B4ENSG00000162616DNAJB4chr1:77979175-78017964:+45
ras homolog family member CENSG00000155366RHOCchr1:112701106-112707434:-512
membrane associated guanylate kinase, WW and PDZ domain containing 3ENSG00000081026MAGI3chr1:113390749-113685923:+44

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