GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
olfactory receptor family 2 subfamily T member 7 | ENSG00000227152 | OR2T7 | chr1:248441207-248442133:+ | 4 | 4.5 |
TUB like protein 3 | ENSG00000078246 | TULP3 | chr12:2877223-2941140:+ | 5 | 6.5 |
plakophilin 2 | ENSG00000057294 | PKP2 | chr12:32790745-32896840:- | 5 | 8 |
mitogen-activated protein kinase kinase kinase 12 | ENSG00000139625 | MAP3K12 | chr12:53479669-53500063:- | 4 | 4.5 |
ankyrin repeat and sterile alpha motif domain containing 1B | ENSG00000185046 | ANKS1B | chr12:98726457-99984654:- | 4 | 4 |
ADP ribosylation factor 6 | ENSG00000165527 | ARF6 | chr14:49893092-49897054:+ | 4 | 9 |
CASP8 and FADD like apoptosis regulator | ENSG00000003402 | CFLAR | chr2:201116104-201176687:+ | 5 | 5 |
myosin X | ENSG00000145555 | MYO10 | chr5:16661914-16936276:- | 4 | 4 |
neuropeptide Y receptor Y6 (pseudogene) | ENSG00000226306 | NPY6R | chr5:137801193-137810751:+ | 4 | 4.5 |
cyclase associated actin cytoskeleton regulatory protein 2 | ENSG00000112186 | CAP2 | chr6:17393216-17557792:+ | 4 | 7 |
TRPM8 channel associated factor 2 | ENSG00000170379 | TCAF2 | chr7:143620950-143730409:+ | 5 | 5 |
cyclin dependent kinase 5 | ENSG00000164885 | CDK5 | chr7:151053812-151058530:- | 4 | 6 |
regulating synaptic membrane exocytosis 2 | ENSG00000176406 | RIMS2 | chr8:103500748-104256094:+ | 5 | 5.5 |
protein phosphatase 1 regulatory subunit 16A | ENSG00000160972 | PPP1R16A | chr8:144477969-144502121:+ | 4 | 5 |
tight junction protein 2 | ENSG00000119139 | TJP2 | chr9:69121264-69255208:+ | 5 | 7.5 |
regulator of solute carriers 1 | ENSG00000215695 | RSC1A1 | chr1:15659869-15661722:+ | 4 | 4 |
RAB3B, member RAS oncogene family | ENSG00000169213 | RAB3B | chr1:51907956-51990764:- | 5 | 9 |
DnaJ heat shock protein family (Hsp40) member B4 | ENSG00000162616 | DNAJB4 | chr1:77979175-78017964:+ | 4 | 5 |
ras homolog family member C | ENSG00000155366 | RHOC | chr1:112701106-112707434:- | 5 | 12 |
membrane associated guanylate kinase, WW and PDZ domain containing 3 | ENSG00000081026 | MAGI3 | chr1:113390749-113685923:+ | 4 | 4 |
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