membrane associated guanylate kinase, WW and PDZ domain containing 3
Location:
1p13.2
Also known as:
MAGI-3
Entrez ID:
260425
Ensembl ID:
ENSG00000081026
Summary:
Overall distribution
Tissue specific distribution
Overall distribution
Tissue specific distribution
Gscore (Amp):
0.00
Gscore (Del):
0.48
Recurrently deleted in 3 cancer type(s)
Overall distribution
Tissue specific distribution
Mscore:
0.00
Overall
Tissue specific
Total fusion occurrence:
6
Fusions detected in 3 cancer type(s)
Overall
Tissue specific
Functional class:
Enzyme
JensenLab PubMed score:
18.05 (Percentile rank: 45.72%)
PubTator score:
14.49 (Percentile rank: 46.41%)
Target development/druggability level:
TbioThese targets do not have known drug or small molecule activities that satisfy the activity thresholds detailed below AND satisfy one or more of the following criteria: 1) target is above the cutoff criteria for Tdark; 2) target is annotated with a Gene Ontology Molecular Function or Biological Process leaf term(s) with an Experimental Evidence code.
Tractability (small molecule):
N/A
Tractability (antibody):
Predicted Tractable - Medium to low confidenceTargets with GO cell component terms plasma membrane or secreted with low or unknown confidence; Targets with predicted signal peptide and transmembrane domains; GO cell component - medium confidence; Human Protein Atlas - high confidence
