GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
chloride voltage-gated channel 5ENSG00000171365CLCN5chrX:49922615-50099235:+57.5
interleukin 1 receptor accessory protein like 2ENSG00000189108IL1RAPL2chrX:104566315-105767829:+45.5
ring finger protein 128ENSG00000133135RNF128chrX:106693794-106796993:+56.5
V-set and immunoglobulin domain containing 1ENSG00000101842VSIG1chrX:108044970-108079184:+45.5
ATPase phospholipid transporting 11CENSG00000101974ATP11CchrX:139726346-139945276:-510.5
dispatched RND transporter family member 3ENSG00000204624PTCHD2chr1:11479166-11537584:+45.5
ATPase cation transporting 13A2ENSG00000159363ATP13A2chr1:16985958-17011928:-46.5
protein kinase N2ENSG00000065243PKN2chr1:88684222-88836255:+46.5
phospholipid phosphatase related 4ENSG00000117600LPPR4chr1:99263953-99309590:+56.5
major facilitator superfamily domain containing 14AENSG00000156875HIAT1chr1:100038097-100083377:+45.5
solute carrier family 6 member 17ENSG00000197106SLC6A17chr1:110150486-110202202:+56.5
chromosome 1 open reading frame 162ENSG00000143110C1orf162chr1:111473792-111478512:+45.5
calcium voltage-gated channel subunit alpha1 EENSG00000198216CACNA1Echr1:181413102-181808084:+45.5
Fc fragment of IgM receptorENSG00000162894FCMRchr1:206904386-206923247:-46.5
pecanex 2ENSG00000135749PCNXL2chr1:232983435-233295713:-45.5
patched domain containing 3ENSG00000182077PTCHD3chr10:27398187-27414368:-45.5
collagen type XIII alpha 1 chainENSG00000197467COL13A1chr10:69801931-69964275:+46
carbohydrate sulfotransferase 3ENSG00000122863CHST3chr10:71964365-72013564:+57.5
solute carrier family 17 member 6ENSG00000091664SLC17A6chr11:22338097-22379503:+56.5
membrane spanning 4-domains A6AENSG00000110077MS4A6Achr11:60172014-60184666:-46.5

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