PKN2
Official symbol: | PKN2 |
Full name: | protein kinase N2 |
Location: | 1p22.2 |
Also known as: | PRKCL2, PRK2, STK7, Pak-2 |
Entrez ID: | 5586 |
Ensembl ID: | ENSG00000065243 |
Summary: | |
|
Overall distribution
|
|
Tissue specific distribution
|
|
|
|
|
|
|
|
|
|
Overall distribution
|
|
Tissue specific distribution
|
|
Gscore (Amp): | 0.00 | Gscore (Del): | 0.44 |
|
|
|
Recurrently deleted in 2 cancer type(s) |
|
|
|
|
|
|
Overall distribution
|
|
Tissue specific distribution
|
|
|
|
Recurrently mutated in 1 cancer type(s) |
|
|
|
|
|
|
Overall
|
|
Tissue specific
|
|
Total fusion occurrence: | 3 |
|
|
Fusions detected in 2 cancer type(s) |
|
|
|
|
|
Functional class: | Kinase (protein kinase) |
JensenLab PubMed score: | 103.65 (Percentile rank: 73.16%) |
PubTator score: | 40.76 (Percentile rank: 64.57%) |
Target development/druggability level: | TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below. |
Tractability (small molecule): | Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands |
Tractability (antibody): | Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted |