GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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| HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
| lymphocyte antigen 6 family member E | ENSG00000160932 | LY6E | chr8:143017982-143023832:+ | 6 | 8.5 |
| X-prolyl aminopeptidase 2 | ENSG00000122121 | XPNPEP2 | chrX:129738974-129769538:+ | 5 | 5 |
| slingshot protein phosphatase 1 | ENSG00000084112 | SSH1 | chr12:108778192-108857590:- | 6 | 8 |
| protein kinase C alpha | ENSG00000154229 | PRKCA | chr17:66302636-66810743:+ | 5 | 10.5 |
| phosphodiesterase 4A | ENSG00000065989 | PDE4A | chr19:10416773-10469631:+ | 5 | 5 |
| UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 | ENSG00000179913 | B3GNT3 | chr19:17794828-17813082:+ | 6 | 7 |
| heparan sulfate 6-O-sulfotransferase 1 | ENSG00000136720 | HS6ST1 | chr2:128236716-128318577:- | 5 | 6 |
| G protein subunit alpha i2 | ENSG00000114353 | GNAI2 | chr3:50226292-50259355:+ | 6 | 15 |
| myosin light chain kinase | ENSG00000065534 | MYLK | chr3:123610049-123884331:- | 6 | 9.5 |
| catenin alpha 1 | ENSG00000044115 | CTNNA1 | chr5:138610967-138935034:+ | 5 | 11 |
| family with sequence similarity 126 member A | ENSG00000122591 | FAM126A | chr7:22889371-23014130:- | 6 | 7 |
| CD160 molecule | ENSG00000117281 | CD160 | chr1:145719471-145739288:+ | 6 | 7 |
| G protein-coupled receptor kinase 5 | ENSG00000198873 | GRK5 | chr10:119207589-119459742:+ | 5 | 5.5 |
| contactin 5 | ENSG00000149972 | CNTN5 | chr11:99020953-100358885:+ | 5 | 6.5 |
| RAS guanyl releasing protein 1 | ENSG00000172575 | RASGRP1 | chr15:38488103-38565575:- | 5 | 6 |
| IQ motif containing GTPase activating protein 1 | ENSG00000140575 | IQGAP1 | chr15:90388218-90502243:+ | 5 | 12 |
| serine protease 21 | ENSG00000007038 | PRSS21 | chr16:2817180-2826304:+ | 5 | 7 |
| LY6/PLAUR domain containing 4 | ENSG00000273111 | LYPD4 | chr19:41837074-41844697:- | 5 | 5 |
| symplekin | ENSG00000125755 | SYMPK | chr19:45815410-45863290:- | 5 | 9.5 |
| cripto, FRL-1, cryptic family 1 | ENSG00000136698 | CFC1 | chr2:130592168-130599575:- | 5 | 5 |
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