GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
cholinergic receptor nicotinic alpha 4 subunitENSG00000101204CHRNA4chr20:63343223-63378401:-810.5
transmembrane serine protease 6ENSG00000187045TMPRSS6chr22:37065436-37109563:-78.5
T cell receptor associated transmembrane adaptor 1ENSG00000163519TRAT1chr3:108822698-108855005:+78.5
mucin 13, cell surface associatedENSG00000173702MUC13chr3:124905442-124953819:-78.5
extended synaptotagmin 3ENSG00000158220ESYT3chr3:138434586-138481686:+89.5
transmembrane serine protease 11DENSG00000153802TMPRSS11Dchr4:67820876-67884032:-78.5
epiregulinENSG00000124882EREGchr4:74365143-74388751:+78.5
betacellulinENSG00000174808BTCchr4:74744759-74794686:-79.5
endomucinENSG00000164035EMCNchr4:100395341-100880126:-78.5
cadherin 18ENSG00000145526CDH18chr5:19472951-20575873:-89.5
cadherin 12ENSG00000154162CDH12chr5:21750673-22853622:-89.5
semaphorin 6AENSG00000092421SEMA6Achr5:116443616-116574934:-89.5
multiple EGF like domains 10ENSG00000145794MEGF10chr5:127290831-127465737:+78.5
protocadherin alpha 1ENSG00000204970PCDHA1chr5:140786136-141012347:+89.5
protocadherin alpha 4ENSG00000204967PCDHA4chr5:140806929-141012344:+89.5
protocadherin gamma subfamily A, 1ENSG00000204956PCDHGA1chr5:141330571-141512981:+810.5
protocadherin gamma subfamily A, 4ENSG00000262576PCDHGA4chr5:141355025-141512979:+89.5
solute carrier family 36 member 1ENSG00000123643SLC36A1chr5:151437046-151492381:+79
gamma-aminobutyric acid type A receptor subunit beta2ENSG00000145864GABRB2chr5:161288429-161549044:-810.5
cadherin related family member 2ENSG00000074276CDHR2chr5:176542511-176595974:+78.5

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