GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
sodium voltage-gated channel beta subunit 2ENSG00000149575SCN2Bchr11:118161951-118176673:-811.5
solute carrier organic anion transporter family member 1B3ENSG00000111700SLCO1B3chr12:20810702-20916911:+911
G protein-coupled receptor 176ENSG00000166073GPR176chr15:39799023-39920892:-811
aquaporin 4ENSG00000171885AQP4chr18:26852038-26865818:-912.5
meprin A subunit betaENSG00000141434MEP1Bchr18:32185069-32220404:+810.5
adhesion G protein-coupled receptor E3ENSG00000131355ADGRE3chr19:14619117-14690027:-912
cytotoxic T-lymphocyte associated protein 4ENSG00000163599CTLA4chr2:203867786-203873960:+810.5
G protein-coupled receptor 1ENSG00000183671GPR1chr2:206175316-206218047:-911
erb-b2 receptor tyrosine kinase 4ENSG00000178568ERBB4chr2:211375717-212538841:-911.5
glycophorin A (MNS blood group)ENSG00000170180GYPAchr4:144109303-144140751:-811.5
endothelial cell surface expressed chemotaxis and apoptosis regulatorENSG00000249751ECSCRchr5:139448556-139462743:-89.5
adhesion G protein-coupled receptor B3ENSG00000135298ADGRB3chr6:68635367-69389511:+911
claudin 4ENSG00000189143CLDN4chr7:73799542-73832693:+912.5
frizzled class receptor 1ENSG00000157240FZD1chr7:91264364-91271326:+912
adhesion G protein-coupled receptor A2ENSG00000020181ADGRA2chr8:37784191-37844896:+811
gastrin releasing peptide receptorENSG00000126010GRPRchrX:16123556-16153021:+911
G protein-coupled receptor 173ENSG00000184194GPR173chrX:53049091-53080615:+911
interferon lambda receptor 1ENSG00000185436IFNLR1chr1:24154157-24187959:-911.5
MPL proto-oncogene, thrombopoietin receptorENSG00000117400MPLchr1:43337807-43352772:+810.5
LDL receptor related protein 8ENSG00000157193LRP8chr1:53242364-53328070:-811.5

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