GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
calcium/calmodulin dependent protein kinase II gammaENSG00000148660CAMK2Gchr10:73812501-73874591:-48.5
sterol-C5-desaturaseENSG00000109929SC5Dchr11:121292453-121308694:+45.5
junctophilin 4ENSG00000092051JPH4chr14:23568035-23578800:-45
zinc finger DHHC-type palmitoyltransferase 22ENSG00000177108ZDHHC22chr14:77131270-77142734:-45.5
ryanodine receptor 3ENSG00000198838RYR3chr15:33310962-33866102:+46.5
phosphatidylinositol glycan anchor biosynthesis class BENSG00000069943PIGBchr15:55318960-55355648:+47.5
NODAL modulator 1ENSG00000103512NOMO1chr16:14833681-14896160:+48
ATPase secretory pathway Ca2+ transporting 2ENSG00000064270ATP2C2chr16:84368527-84464187:+45.5
phospholipid scramblase 3ENSG00000187838TMEM256-PLSCR3chr17:7389727-7394843:-47.5
secretory carrier membrane protein 4ENSG00000227500SCAMP4chr19:1905214-1926013:+48.5
ryanodine receptor 1ENSG00000196218RYR1chr19:38433699-38587564:+46.5
NCK associated protein 1ENSG00000061676NCKAP1chr2:182909115-183038858:-47
Ig-like domain-containing proteinENSG00000277117ICOSLGchr21:5022493-5040666:+46.5
lipase maturation factor 2ENSG00000100258LMF2chr22:50502949-50507691:-410.5
phospholipid scramblase 4ENSG00000114698PLSCR4chr3:146192339-146251179:-46
steroid 5 alpha-reductase 3ENSG00000128039SRD5A3chr4:55346109-55373096:+46.5
secretory carrier membrane protein 1ENSG00000085365SCAMP1chr5:78360583-78479071:+47.5
monooxygenase DBH like 1ENSG00000079931MOXD1chr6:132296055-132401545:-49
dpy-19 like 4ENSG00000156162DPY19L4chr8:94719703-94793836:+46.5
ryanodine receptor 2ENSG00000198626RYR2chr1:237042205-237833988:+45.5

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