Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
HLA-GENSG00000204632                                                                                                                                    
STAMBPENSG00000124356                                                                                                                                    
TSG101ENSG00000074319                                                                                                                                    
PTPN4ENSG00000088179      1                                                                                                                              
FASENSG00000026103                                                                                                                                    
NOTCH2ENSG00000134250                                                                                                                                    
ATP8B2ENSG00000143515                                                                                                                                    
PKD2ENSG00000118762                                                                                                                                    
IFNGR1ENSG00000027697                                                                                                                                    
IL6STENSG00000134352                                                              1                                                                      
PTK2BENSG00000120899                                                                                                                                    
SULF1ENSG00000137573                                                                                                                                    
CDC42ENSG00000070831                                                                                                                                    
VIMENSG00000026025                                                                                                                                    
PIK3C2AENSG00000011405                                                                                                                                    
INSRENSG00000171105                                                                                                                                    
CACNA1DENSG00000157388                                                                                                                                    
ITPR3ENSG00000096433                                                                                                                                    
PIP5K1AENSG00000143398                                                                                                                                    
MAP3K12ENSG00000139625                                                                                                                                    

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