phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
Location:
1q21.3
Also known as:
Entrez ID:
8394
Ensembl ID:
ENSG00000143398
Summary:
Overall distribution
Tissue specific distribution
Overall distribution
Tissue specific distribution
Gscore (Amp):
2.46 (Driver)
Gscore (Del):
0.00
Recurrently amplified in 9 cancer type(s)
Overall distribution
Tissue specific distribution
Mscore:
0.00
Overall
Tissue specific
Total fusion occurrence:
4
Fusions detected in 3 cancer type(s)
Overall
Tissue specific
Functional class:
Kinase
JensenLab PubMed score:
5.88 (Percentile rank: 28.81%)
PubTator score:
15.73 (Percentile rank: 47.86%)
Target development/druggability level:
TbioThese targets do not have known drug or small molecule activities that satisfy the activity thresholds detailed below AND satisfy one or more of the following criteria: 1) target is above the cutoff criteria for Tdark; 2) target is annotated with a Gene Ontology Molecular Function or Biological Process leaf term(s) with an Experimental Evidence code.
Tractability (small molecule):
Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands
Tractability (antibody):
Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted
