Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
KDM7AENSG00000006459                                                                                                                                    
KMT2CENSG00000055609      1    1    1    1                1                                1    1                    1            1                              
ELP3ENSG00000134014                                                                                                                          1          
WHSC1L1ENSG00000147548                                                                                                                                    
KAT6AENSG00000083168                                                                                                                                    
PRDM14ENSG00000147596                                                                                                                                    
ATAD2ENSG00000156802                                                                  1                                        1                          
KIAA2026ENSG00000183354                                                                                                                                    
UHRF2ENSG00000147854                                                                                                                                    
PSIP1ENSG00000164985      1                                                                                                                              
PHF24ENSG00000122733                                                                                                                                    
SPIN1ENSG00000106723                                                                                                                                    
PHF2ENSG00000197724                                                                                                                                    
TDRD7ENSG00000196116                                                                                                                                    
PHF19ENSG00000119403                                                                                                                                    
PRDM12ENSG00000130711                                                                                                                                    
MSL3ENSG00000005302                                                                                                                                    
SCML2ENSG00000102098                                                                                                                                    
JADE3ENSG00000102221          1                                                                                                                1          
SPIN2BENSG00000186787                                                                                                                                    

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