PDGs

 

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationTDLPubTator Score
olfactory receptor family 1 subfamily S member 1ENSG00000280204OR1S1chr11:58214745-58215723:+Tdark0
olfactory receptor family 12 subfamily D member 2ENSG00000280236OR12D2chr6:29396555-29397671:+Tdark0.75
olfactory receptor family 8 subfamily K member 3 (gene/pseudogene)ENSG00000280314OR8K3chr11:56318307-56319245:+Tdark0

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