PDGs
The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .
| Showing page 299 |
first page | previous page | next page | last page |
| HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | TDL | PubTator Score |
| olfactory receptor family 4 subfamily K member 13 | ENSG00000176253 | OR4K13 | chr14:20033844-20034760:- | Tdark | 0 |
| olfactory receptor family 10 subfamily A member 7 | ENSG00000179919 | OR10A7 | chr12:55221025-55221975:+ | Tdark | 2.2 |
| olfactory receptor family 52 subfamily K member 1 | ENSG00000196778 | OR52K1 | chr11:4488879-4489908:+ | Tdark | 0 |
| olfactory receptor family 1 subfamily L member 6 | ENSG00000171459 | OR1L6 | chr9:122749740-122750783:+ | Tdark | 6.5 |
| taste 2 receptor member 39 | ENSG00000236398 | TAS2R39 | chr7:143183419-143184435:+ | Tbio | 7.95 |
| olfactory receptor family 2 subfamily A member 14 | ENSG00000221938 | OR2A14 | chr7:144109583-144130069:+ | Tdark | 2.6 |
| olfactory receptor family 13 subfamily C member 9 | ENSG00000136839 | OR13C9 | chr9:104617248-104618204:- | Tdark | 1 |
| olfactory receptor family 4 subfamily C member 11 | ENSG00000172188 | OR4C11 | chr11:55603354-55604398:- | Tdark | 0 |
| olfactory receptor family 6 subfamily C member 4 | ENSG00000179626 | OR6C4 | chr12:55551199-55552244:+ | Tdark | 0 |
| olfactory receptor family 2 subfamily AP member 1 | ENSG00000179615 | OR2AP1 | chr12:55574415-55575344:+ | Tdark | 0 |
| olfactory receptor family 5 subfamily M member 8 | ENSG00000181371 | OR5M8 | chr11:56490435-56491370:- | Tdark | 0 |
| olfactory receptor family 8 subfamily H member 3 | ENSG00000181761 | OR8H3 | chr11:56122373-56123311:+ | Tdark | 0 |
| olfactory receptor family 4 subfamily B member 1 | ENSG00000175619 | OR4B1 | chr11:48216792-48217762:+ | Tdark | 0.25 |
| defensin beta 113 | ENSG00000214642 | DEFB113 | chr6:49968677-49969625:- | Tdark | 0.25 |
| olfactory receptor family 9 subfamily K member 2 | ENSG00000170605 | OR9K2 | chr12:55129681-55130802:+ | Tdark | 0.2 |
| olfactory receptor family 4 subfamily A member 5 | ENSG00000221840 | OR4A5 | chr11:54706885-54707832:+ | Tdark | 0 |
| olfactory receptor family 4 subfamily D member 6 | ENSG00000166884 | OR4D6 | chr11:59456938-59457991:+ | Tdark | 0.5 |
| olfactory receptor family 4 subfamily F member 5 | ENSG00000186092 | OR4F5 | chr1:69091-70008:+ | Tdark | 0 |
| olfactory receptor family 5 subfamily D member 16 | ENSG00000205029 | OR5D16 | chr11:55838752-55839738:+ | Tdark | 0 |
| olfactory receptor family 6 subfamily C member 76 | ENSG00000185821 | OR6C76 | chr12:55426254-55427192:+ | Tdark | 0 |
|
Showing page 299 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.