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PDGs

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome

Show entries each page Jump to page Total Page: 305 Total entries: 6083
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HGNC Name	Ensembl Gene ID	HGNC Symbol	Genomic Location	TDL	PubTator Score
solute carrier family 25 member 21	ENSG00000183032	SLC25A21	chr14:36677921-37172866:-	Tbio	3.36786
cystatin 9 like	ENSG00000101435	CST9L	chr20:23564732-23568749:-	Tbio	4.07143
eyes shut homolog	ENSG00000188107	EYS	chr6:63719980-65707225:-	Tbio	106.921
olfactory receptor family 51 subfamily A member 4	ENSG00000205497	OR51A4	chr11:4946159-4947100:-	Tdark	0.142857
olfactory receptor family 2 subfamily T member 33	ENSG00000177212	OR2T33	chr1:248272852-248273814:-	Tdark	26.5
microseminoprotein, prostate associated	ENSG00000215183	MSMP	chr9:35752990-35756613:-	Tdark	7.44444
serpin family B member 12	ENSG00000166634	SERPINB12	chr18:63556160-63567011:+	Tbio	2.47619
lactalbumin alpha	ENSG00000167531	LALBA	chr12:48567684-48570066:-	Tbio	36.3579
olfactory receptor family 5 subfamily P member 2	ENSG00000183303	OR5P2	chr11:7795905-7796973:-	Tdark	0.361111
olfactory receptor family 6 subfamily N member 1	ENSG00000197403	OR6N1	chr1:158765744-158766682:-	Tdark	44.3167
MAS1 proto-oncogene, G protein-coupled receptor	ENSG00000130368	MAS1	chr6:159906690-159916530:+	Tbio	42.0953
guanylate cyclase 1 soluble subunit beta 2 (pseudogene)	ENSG00000123201	GUCY1B2	chr13:50994511-51080862:-	Tclin	2.14286
olfactory receptor family 10 subfamily J member 6 pseudogene	ENSG00000158731	OR10J6P	chr1:159598298-159599227:+	Tdark	0
serine protease 30, pseudogene	ENSG00000172460	PRSS30P	chr16:2839568-2842744:-		0
serine protease 41	ENSG00000215148	PRSS41	chr16:2798485-2805132:+	Tdark	0
adhesion G protein-coupled receptor E4, pseudogene	ENSG00000268758	ADGRE4P	chr19:6952500-6990846:-	Tdark	0.666667
arylacetamide deacetylase like 2	ENSG00000197953	AADACL2	chr3:151733916-151761339:+	Tdark	0.333333
G protein-coupled receptor 101	ENSG00000165370	GPR101	chrX:137030148-137031674:-	Tbio	14.0499
serine peptidase inhibitor, Kunitz type 4	ENSG00000149651	SPINT4	chr20:45722351-45725830:+	Tdark	1.33333
serine protease 58	ENSG00000258223	PRSS58	chr7:142252143-142258058:-	Tdark	0

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