PDGs
The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .
| Showing page 276 |
first page | previous page | next page | last page |
| HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | TDL | PubTator Score |
| solute carrier family 26 member 5 | ENSG00000170615 | SLC26A5 | chr7:103352730-103446177:- | Tbio | 49.9809 |
| olfactory receptor family 56 subfamily A member 3 | ENSG00000184478 | OR56A3 | chr11:5947340-5948361:+ | Tdark | 0 |
| cation channel sperm associated 4 | ENSG00000188782 | CATSPER4 | chr1:26190561-26202968:+ | Tchem | 0.972222 |
| olfactory receptor family 13 subfamily A member 1 | ENSG00000256574 | OR13A1 | chr10:45302654-45315608:- | Tdark | 0 |
| tectorin beta | ENSG00000119913 | TECTB | chr10:112283735-112305035:+ | Tbio | 0.807575 |
| kelch like family member 40 | ENSG00000157119 | KLHL40 | chr3:42685519-42692544:+ | Tbio | 3.30119 |
| cysteine rich secretory protein 2 | ENSG00000124490 | CRISP2 | chr6:49692358-49713590:- | Tbio | 29.8524 |
| ring finger protein 17 | ENSG00000132972 | RNF17 | chr13:24764152-24879921:+ | Tdark | 4.5547 |
| motilin receptor | ENSG00000102539 | MLNR | chr13:49220338-49222377:+ | Tchem | 38.6667 |
| collagen type XIX alpha 1 chain | ENSG00000082293 | COL19A1 | chr6:69866571-70209976:+ | Tbio | 3.53095 |
| tubulin alpha 8 | ENSG00000183785 | TUBA8 | chr22:18110331-18146554:+ | Tbio | 5.83016 |
| CEA cell adhesion molecule 16, tectorial membrane component | ENSG00000213892 | CEACAM16 | chr19:44699151-44710714:+ | Tbio | 9.14444 |
| WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | ENSG00000173714 | WFIKKN2 | chr17:50834650-50842348:+ | Tbio | 5.09167 |
| gamma-aminobutyric acid type A receptor subunit rho3 | ENSG00000183185 | GABRR3 | chr3:97986673-98035304:- | Tdark | 45.9417 |
| serine protease 38 | ENSG00000185888 | PRSS38 | chr1:227815693-227846470:+ | Tdark | 3.33333 |
| olfactory receptor family 56 subfamily B member 4 | ENSG00000180919 | OR56B4 | chr11:6107684-6108835:+ | Tdark | 1 |
| osteocrin | ENSG00000188729 | OSTN | chr3:191199241-191265615:+ | Tbio | 11.2583 |
| melanin concentrating hormone receptor 2 | ENSG00000152034 | MCHR2 | chr6:99919910-99994247:- | Tchem | 55.7968 |
| pancreatic lipase related protein 1 | ENSG00000187021 | PNLIPRP1 | chr10:116590385-116609175:+ | Tbio | 7.68125 |
| olfactory receptor family 1 subfamily G member 1 | ENSG00000183024 | OR1G1 | chr17:3126584-3127581:- | Tdark | 8.4 |
|
Showing page 276 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.