PDGs
The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .
| Showing page 270 |
first page | previous page | next page | last page |
| HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | TDL | PubTator Score |
| chorionic gonadotropin subunit beta 7 | ENSG00000196337 | CGB7 | chr19:49054275-49058860:- | Tdark | 3.91667 |
| gamma-aminobutyric acid type A receptor subunit alpha4 | ENSG00000109158 | GABRA4 | chr4:46918900-46994407:- | Tclin | 17.5671 |
| C1q and TNF related 5 | ENSG00000223953 | C1QTNF5 | chr11:119338942-119340883:- | Tbio | 37.3174 |
| interleukin 1 receptor accessory protein like 1 | ENSG00000169306 | IL1RAPL1 | chrX:28587399-29956723:+ | Tbio | 44.0728 |
| dehydrogenase/reductase 7C | ENSG00000184544 | DHRS7C | chr17:9771434-9791297:- | Tdark | 1.625 |
| transmembrane serine protease 15 | ENSG00000154646 | TMPRSS15 | chr21:18269116-18485879:- | Tchem | 11.8667 |
| ADAM metallopeptidase domain 29 | ENSG00000168594 | ADAM29 | chr4:174829668-174978180:+ | Tbio | 11.5291 |
| kinase suppressor of ras 2 | ENSG00000171435 | KSR2 | chr12:117453012-117968983:- | Tbio | 16.2877 |
| olfactory receptor family 11 subfamily A member 1 | ENSG00000204694 | OR11A1 | chr6:29425504-29457071:- | Tdark | 1.05 |
| prolactin releasing hormone | ENSG00000071677 | PRLH | chr2:237566574-237567175:+ | Tdark | 59.1353 |
| serine protease 55 | ENSG00000184647 | PRSS55 | chr8:10525546-10554166:+ | Tdark | 5.92064 |
| interferon alpha 7 | ENSG00000214042 | IFNA7 | chr9:21201469-21202205:- | Tdark | 10.3345 |
| G protein-coupled receptor 50 | ENSG00000102195 | GPR50 | chrX:151176653-151181465:+ | Tbio | 73.5265 |
| testis expressed 14, intercellular bridge forming factor | ENSG00000121101 | TEX14 | chr17:58556678-58692055:- | Tbio | 6.47339 |
| chorionic gonadotropin subunit beta 3 | ENSG00000104827 | CGB | chr19:49022869-49024333:- | 0 | |
| Wnt family member 8B | ENSG00000075290 | WNT8B | chr10:100463041-100483744:+ | Tbio | 11.0429 |
| olfactory receptor family 2 subfamily T member 4 | ENSG00000196944 | OR2T4 | chr1:248361581-248362627:+ | Tdark | 38.5833 |
| glycine receptor alpha 2 | ENSG00000101958 | GLRA2 | chrX:14529298-14731812:+ | Tchem | 21.325 |
| BPI fold containing family B member 6 | ENSG00000167104 | BPIFB6 | chr20:33031648-33044047:+ | Tdark | 1.03333 |
| adhesion G protein-coupled receptor G4 | ENSG00000156920 | ADGRG4 | chrX:136300963-136416888:+ | Tdark | 1.94698 |
|
Showing page 270 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.