PDGs

 

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome


 Show   entries each page
 Jump to page  

 Total Page: 305 Total entries: 6083
  
 Showing page 263  first page | previous page | next page | last page 
 
HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationTDLPubTator Score
PR/SET domain 9ENSG00000164256PRDM9chr5:23507155-23528597:+Tbio69.2444
casein kinase 1 alpha 1 likeENSG00000180138CSNK1A1Lchr13:37103259-37105664:-Tdark104.778
dual specificity phosphatase 13ENSG00000079393DUSP13chr10:75094432-75109221:-Tbio10.8667
glutamate metabotropic receptor 5ENSG00000168959GRM5chr11:88504576-89065945:-Tchem75.4641
olfactory receptor family 51 subfamily C member 1 pseudogeneENSG00000197674OR51C1Pchr11:4690761-4691702:-0
polycystin 1 like 3, transient receptor potential channel interactingENSG00000277481PKD1L3chr16:71929538-71999978:-Tbio10.0012
cholinergic receptor nicotinic alpha 6 subunitENSG00000147434CHRNA6chr8:42752620-42796392:-Tchem16.0924
histamine receptor H4ENSG00000134489HRH4chr18:24460629-24479957:+Tchem146.582
matrix metallopeptidase 27ENSG00000137675MMP27chr11:102691487-102705806:-Tbio2.46075
lipase family member KENSG00000204021LIPKchr10:88724544-88752786:+Tdark4.1
C1q and TNF related 8ENSG00000184471C1QTNF8chr16:1090005-1096244:-Tdark2.625
zinc activated ion channelENSG00000186919ZACNchr17:76071961-76083666:+Tchem12.7083
retinal pigment epithelium-derived rhodopsin homologENSG00000180245RRHchr4:109827994-109844604:+Tbio20.5231
spindlin family member 2AENSG00000147059SPIN2AchrX:57134530-57137625:-Tdark53.0417
potassium voltage-gated channel modifier subfamily S member 2ENSG00000156486KCNS2chr8:98427022-98432848:+Tclin1.00952
cholinergic receptor nicotinic gamma subunitENSG00000196811CHRNGchr2:232539727-232546403:+Tclin17.5763
SH3 domain binding kinase family member 2ENSG00000187550SBK2chr19:55529733-55537089:-Tdark2.83333
olfactory receptor family 7 subfamily A member 5ENSG00000188269OR7A5chr19:14792490-14835376:-Tdark0.111111
olfactory receptor family 2 subfamily B member 11ENSG00000177535OR2B11chr1:247451029-247451982:-Tdark0.5
polycystin family receptor for egg jellyENSG00000130943PKDREJchr22:46255663-46263355:-Tdark5.675

 Showing page 263  		first page | previous page | next page | last page 








Contact us | | Terms & Conditions.
Copyright © 2020 University of Pennsylvania. All Rights Reserved.