Expression

 

Positive expression of a PDG in a given cancer type was defined as its mRNA expression was reliably detected in at least 50% of tumor specimens (i.e., the 50th percentile of fragments per kilobase of transcript per million mapped reads [FPKM] value ≥1).

 

Summary of PDG mRNA expression levels (FPKM value) in each cancer type


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HGNC Ensembl No. Detectable ACCBLCABRCACESCCHOLCOADDLBCESCAGBMHNSCKICHKIRCKIRPLAMLLGGLIHCLUADLUSCMESOOVPAADPCPGPRADREADSARCSKCMSTADTGCTTHCATHYMUCECUCSUVM
SymbolGene IDCancer Types25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th
CTSBENSG000001647333394.46171.9295.13452.9213.75356.53581.361008.37274.76370.88520.03698.43379.99550.1797.571135.05236.69345.43484.77564.88261.56362.55540.62686.37515.56934.341376.391951.43288.05408.54684.24976.75336.28484.38651.81197.91419.59588.11852.31256.76170.18260.57364.71587.97313.93430.3601.89838366.94533.37834.581386.4171.11109.89170.39291.13164.04207.99284.08395.07234.96343.34509.14726.14391.14553.02848.381197.99462.52734.161158.211728.14334.41450.79683.861054.78310.12432.75646.97836.59362.55505.9671.32851.06102.35137.42197.88264.69129.64183.34256.99326.46257.64324.64496.83643.63294.66527.94961.221400.3519.54864.131421.992171.26274.98399.43588.35856.52220.35311.42457.85648.052559.153761.265362.446711.9798.26144.72226.55345.86339.93504.11728.151170.33189.05277.57473.26610.83311.94406.5563.73729.81
VEGFAENSG000001127153346.7575.87117.7174.0837.9371.63128.83212.0625.9539.3260.6597.9241.0369.04115.47196.0372.7797.25146.01216.4350.2269.3995.59121.794.226.9211.4219.134.6652.887.86164.6565.3154.03282.93503.0528.9245.7774.29114.354.5175.17108.12134.34375.21633.59983.991318.5211.4517.5834.3680.633.97.6117.0737.949.3914.0321.8737.8229.4846.0171.65105.2256.4594.21147.03230.1355.3580.72128.47187.1124.9741.5972.19124.9141.0964.96103.86157.0244.3670.0899.96140.1833.659.92107.14182.6327.0156.36115.43180.0849.1971.05100.94142.7418.9335.5871.76150.411.6520.4141.1176.5729.5849.1676.02116.167.413.5131.1155.6967.76119.46190.21260.45.6413.225.0947.8131.2453.1296.28137.7227.2452.0782.16150.933.475.349.2719.47
SCDENSG000000991943331.693.74192.24306.4524.1848.1493183.2836.3280.64160.54289.2935.4967.27107.42186.3918.2429.0454.1966.0352.5188.87132.14210.0111.216.8227.0534.1626.8255.4491.82151.839.0961.7482.26121.3335.6663.95107.16177.6713.4831.3470.37128.5642.8271.39107.17160.618.7116.7729.9150.811.253.216.3911.57128.82216.38328.74483.6276.71190.24394.09703.1136.9961.4796.09155.1758.5693.22137.69220.27.2714.7829.2570.579.4717.7930.7855.3120.4729.1148.5270.819.8318.1333.9358.9933.5261.7106.39183.3668.4596.08129.75193.546.5713.0225.1148.3254.5298.68157.98238.8516.2533.1167.71106.1328.7646.2267.3898.642.044.166.59.146.0510.0516.2825.0523.2237.0765.45112.8221.77324452.7665.92109.02134.95179.02
KDRENSG00000128052322.484.437.812.741.452.353.695.094.146.248.9912.420.741.242.183.551.673.054.926.421.752.823.985.660.671.342.263.031.82.785.058.753.114.165.618.211.162.133.685.554.136.8612.7216.0318.7538.3459.8586.550.681.131.854.80.020.060.260.571.92.944.566.981.713.575.68.364.297.4613.122.951.72.643.945.6810.6721.0648.6486.481.11.672.483.272.64.096.098.315.169.0314.223.222.193.635.868.042.053.545.046.693.325.9610.0216.261.883.015.098.992.714.286.559.241.322.776.7810.376.912.2920.6529.51.12.164.818.611.452.093.295.111.712.643.986.340.851.312.353.89
ITGB1ENSG000001500933370.4392.13128.29174.02102.76141.34208.54283.92137.05183.91236.57303.0682.41121.26168.07238.64237.84347.54544.12669.78124.08150.96193.88237.0125.8638.1365.5391.07118.39165.33228.17304.8953.2772.898.58130.08104.01145.12204.54300.6742.6556.6969.390.78171.36216.51277.61357.3887.49121.29160.46228.2348.1764.780.4295.1826.5133.8445.4964.574.65105.7144.86210.33135.88176.77238.9345.02112.18150.6203.04276.24122.21167.72260.34320.4570.5596.28129.86168.34196.22281.54345.44447.23132.61172.46218.79281.5386.46110.51135.52164.08130.62156.25182.56209.87143.66219.65327.8492.3476.75117.09175.78244.61129.98167.96238.89318.6474.195.7124.17153.1188108.67135.41162.1832.8549.8285.47123.9595.22137.29187.25240.53106.15143.99191.07255.3141.0660.7685.28110.33
SLC2A1ENSG000001173943313.9621.7641.7878.6380.77167344.9962330.0844.672.26118.12123.07243.93476.31745.587.1613.9227.6884.0660.83103.94168.52270.9313.5119.727.0135.2783.63205.97425.6392260.1486.46119.94202.52293.44510.33816.411089.329.7215.1927.4361.384.83128.67191.09284.8811.3720.2733.7295.0717.5127.737.8266.9347.6661.0878.23100.861.142.385.2412.6427.4556.03124.53229.38254.59435.05764.951155.3314.9633.6960.44123.398.46169.13264.21405.8649.95108.09207.6401.555.047.0413.2630.5120.7726.8534.4240.9864.392.05170.89329.859.520.0539.62102.0420.334.862.6109.7831.6355.98109.97215.5930.4549.95175.64346.0515.9721.2428.3236.377.8712.9418.0334.8541.6890.62157.39262.0344.9365.49140.94261.0814.419.4326.6139.67
EGFENSG0000013879850.110.320.791.850.040.110.270.860.51.393.196.060.050.110.320.900.040.20.580.080.240.872.600.010.040.090.080.240.821.820.571.131.852.590.120.290.71.5516.129.9944.7459.550.320.842.294.240.40.791.483.190.110.30.912.550.320.591.011.6700.020.191.30.651.73.466.20.380.92.143.680.130.240.380.890.060.120.240.430.120.360.932.2500.010.040.071.122.324.297.140.060.130.391.020.040.20.722.30.110.350.951.80.010.060.180.590.190.330.670.930.180.320.621.270.010.040.120.310.080.240.691.680.130.230.520.810.060.110.270.97
PDK1ENSG00000152256322.174.287.5115.322.944.346.039.122.583.896.1910.113.75.177.3510.741.292.173.935.483.665.27.319.412.934.595.637.265.427.6210.8115.863.314.727.8411.244.196.469.6213.771.72.443.755.769.9213.8419.125.22.293.445.438.697.5710.5216.1122.581.251.732.293.141.662.694.036.633.85.789.0712.568.211.4317.323.622.222.894.14.965.518.4312.2917.332.223.084.245.842.172.773.588.382.43.013.95.13.394.656.277.61.622.854.556.942.553.976.569.954.075.678.3211.744.776.488.8510.541.511.832.333.411.872.333.194.313.645.538.3211.524.517.2711.9716.50.480.741.42.41
ORC1ENSG00000085840220.270.51.122.11.673.044.656.730.831.542.694.645.57.469.211.511.151.682.633.963.024.516.218.174.676.639.7312.662.523.725.447.931.241.923.134.052.84.166.569.440.060.090.140.250.360.530.731.090.350.480.781.185.117.39.4612.740.180.340.71.470.370.791.663.060.891.692.94.822.914.265.557.60.631.042.133.271.442.223.274.690.580.771.171.790.140.190.280.380.240.330.480.72.593.825.827.831.152.314.016.041.682.654.086.041.762.984.496.326.4710.3816.7129.390.230.330.480.641.874.927.829.381.933.094.256.52.773.654.655.920.350.50.70.91
ADAENSG00000196839323.034.757.1311.133.978.3915.1425.543.414.97.4610.65.611.1819.8330.12.894.35.889.424.16.2210.0514.2851.8497.79180.77217.965.268.2214.2218.953.975.487.2710.551116.6725.2336.310.60.911.612.494.336.219.2714.342.543.555.197.8820.4541.0666.32108.552.683.9468.672.423.995.828.693.265.368.1811.659.2914.8123.7737.425.087.1210.5915.864.66.69.212.294.766.68.6914.640.951.612.995.051.011.42.042.883.545.618.5412.74.878.8915.8529.695.919.8113.6820.134.716.7410.1815.367.159.2812.2814.742.223.014.035.6749.38255.91422.58529.144.096.1711.3917.459.9814.9321.0427.694.145.567.529.77
INSRENSG000001711053313.0418.9727.6931.884.526.248.8711.898.411.515.9421.422.083.384.87.4211.3613.3917.8331.025.677.641013.620.71.231.742.655.769.4516.1421.653.724.966.287.842.413.845.67.6413.2217.4921.4126.0525.0139.8754.667.936.458.1511.2715.4210.3414.6721.633.064.85.656.878.1910.613.5218.5124.395.457.5811.115.373.975.778.1110.343.164.075.015.983.885.58.0310.9210.071316.1220.228.9812.6916.523.988.029.9812.0714.836.377.6310.0611.776.2710.2514.4820.632.874.345.77.379.412.4216.3820.683.474.716.448.4910.8114.1717.8122.832.553.966.6510.152.934.176.159.12.813.975.126.353.363.974.785.81
PIM1ENSG00000137193335.9910.3816.124.0632.854.1889.26134.86.49.8916.0324.323.4737.7256.8888.027.5511.4918.4319.7411.1715.9822.5529.4836.670.3297.84147.1112.8619.2433.5454.958.7712.3617.7425.5524.3735.7451.167.6425.3533.3249.4767.4910.214.3220.328.889.1912.9719.3830.0326.5848.1476.17139.924.626.39.6914.716.2610.2417.5626.4814.820.5328.4936.8216.9626.0439.3153.1829.3142.7166.56111.858.9913.5322.3433.0918.4826.1637.2451.864.686.138.6613.069.1613.120.430.1611.7216.4724.532.715.0924.0537.0552.15.168.7814.624.149.9414.3120.0730.1549.9974.598.97119.964.947.1211.7917.8215.8224.7330.5635.768.5412.5218.129.3411.0416.7526.8633.071.222.113.134.98
STAT5BENSG00000173757338.4711.2517.1122.579.1211.5915.1418.6310.7315.120.0325.378.1910.4513.1716.7910.6413.4215.8117.311.1314.1717.4521.1211.1514.9221.9226.5210.113.1116.3119.2912.1215.9119.4822.256.729.0511.3214.410.7613.5716.3917.9817.3521.8425.8628.8614.2718.8723.128.4945.5156.7371.4787.6117.8921.224.9127.916.999.3811.815.2810.0612.8915.518.578.5111.3314.4817.429.5612.1314.0416.734.516.328.5311.1812.0614.4418.3823.0113.4917.4323.0928.4911.8615.1517.8720.4811.6414.4317.6120.7910.7815.5724.4636.911.4115.519.1724.159.8113.218.224.4110.8614.4718.1321.9915.6518.2220.8523.4513.219.924.2827.346.529.3912.5415.247.210.1813.7116.6610.8914.3416.5921.19
GASTENSG0000018450210000000.20.820000.050.090.432.328.71000.140.4900.080.250.6200000.060.432.468.8200.070.160.280.622.447.0619.7000000000000.04000000.080.160.29000.080.910000.160.140.783.9412.20000.0500.070.270.900.140.441.6600.10.240.47000000.080.230.860000.060000.0500.171.0214.400.110.371.49000000.070.230.76000.180.94000.080.160000
SMARCA2ENSG000000805033318.4926.7637.8947.3516.823.6433.6746.2732.845.0557.4571.2620.4528.3637.4648.5713.220.0526.2736.6220.0925.4831.3535.1324.1238.7450.7275.2911.0116.4221.2627.7221.8529.7536.2545.9414.0220.5130.5548.3319.4827.3235.9238.9123.8830.838.3246.420.6126.8734.6542.3340.0348.4960.157234.5742.653.2766.0210.6915.520.8727.9116.3821.9929.0137.4117.6825.7738.8565.9927.9239.4854.9169.549.4415.1123.7534.4422.9530.5240.5847.7338.0949.6160.473.3134.942.7749.4155.621.0527.6833.8840.3128.9740.952.1465.1615.722.7232.1943.3212.6618.9726.9135.8925.7536.7155.1678.634.2841.7551.261.2534.2141.9155.0370.2114.6622.4631.4342.8313.2421.7935.1142.3525.9333.0844.2755.35
PDGFRBENSG00000113721334.627.3812.9821.154.7310.3721.8234.9419.4132.4548.3763.744.388.2514.1723.914.9718.4526.0842.598.515.8926.4639.296.429.0812.2419.9212.2720.2839.2557.6311.1716.9824.3632.498.1415.4628.0548.255.938.0911.715.8625.4142.9365.3690.681.853.316.913.190.671.442.935.797.49.3412.4517.175.278.8615.1323.5611.9919.1329.7842.329.5316.2626.2942.28.6316.134.759.414.828.6516.0226.432.2551.6872.6490.659.6114.9524.2740.437.5912.1818.8726.099.3115.9224.3443.3931.6556.3191.98156.415.710.0817.2729.9317.0529.0848.51738.3913.0829.0255.228.1412.1618.3225.321.733.056.039.535.659.5615.8423.9212.6923.133.2652.872.073.3968.96
FASLGENSG00000117560200.030.120.420.050.160.461.230.160.350.791.680.270.641.553.170.10.170.341.20.120.280.510.931.563.295.428.680.090.210.460.970.030.060.10.180.110.330.841.890.050.110.210.320.490.891.633.820.090.170.330.630.10.220.421.0500.020.040.10.070.150.290.620.280.521.112.290.180.390.871.610.230.491.061.690.070.190.430.810.10.240.430.790.020.060.110.20.080.130.250.40.110.250.420.60.060.190.531.80.110.431.393.250.210.440.861.690.411.082.033.380.080.170.350.960.10.350.651.660.130.310.781.470.030.070.160.410.010.050.130.89
NR3C1ENSG00000113580335.477.5110.0113.012.094.077.0310.335.187.9911.4316.46.178.3110.9614.766.869.5213.6217.170.941.893.255.5512.4817.6729.640.215.219.1613.1819.178.0910.2511.6914.347.5210.1713.3916.64.617.1410.8913.5316.3922.1628.6236.447.179.5712.3616.4317.8924.5329.6835.9910.1912.4815.6719.497.0810.3715.3422.139.7112.8217.4122.427.149.311.8914.946.918.6410.8812.594.075.977.6710.296.558.7211.8714.917.719.712.7615.694.596.528.812.081.292.023.465.059.541317.8422.665.849.213.3416.863.826.6610.0713.572.193.895.547.587.759.4111.6413.3213.916.919.7924.180.881.964.065.513.555.588.7210.032.143.915.897.58
STAT3ENSG000001686103315.3920.8727.9634.8324.5536.349.4962.6246.6461.9482.38104.8937.6748.763.7381.6631.7938.7347.0354.1633.6942.8953.4864.323.7641.6766.71112.2150.666.0482.8399.7838.1746.6858.7968.544.9759.9777.72100.9413.6417.6824.5631.7339.4749.8559.6268.9129.6542.0652.9163.8650.9860.3373.7785.4526.6332.8641.9855.5519.5527.439.1850.9153.768.0482.62100.444.0254.9872.7990.9948.7261.4574.5292.2132.843.0159.672.6841.5649.6659.2271.2620.127.835.0446.5636.5449.6663.4675.832.5439.7647.2857.8830.5138.9550.6266.5129.5942.0854.0565.745.5259.3373.0190.4117.8125.4235.6742.8932.1742.3449.5358.121.6628.6843.0658.4324.5636.4750.2770.2621.4732.3641.4553.2117.4125.0339.9355.35
NFKB2ENSG00000077150339.8513.5317.5425.7216.6922.2230.6540.3812.851723.0331.2819.8427.0937.3448.5526.3941.0750.9962.2212.5117.1522.9627.2253.7667.4495.48123.5517.7925.836.1851.534.386.028.2210.3917.2222.6530.3442.434.486.39.3314.6117.3123.2831.0342.2714.8219.6325.5235.576.429.2715.0821.713.64.726.588.6912.3218.1126.135.3815.2620.9427.7837.6913.9319.2427.1640.1818.3625.9636.7149.0516.7822.7930.8738.6321.3928.7937.9345.694.516.339.4311.9916.5220.7127.2933.8911.3115.2518.8122.7112.9517.9724.1835.0212.7518.8627.6538.6419.4127.2836.149.6531.1455.5773.9295.3613.2716.3420.3524.2218.8225.8134.6151.7417.6623.5632.5241.8514.2319.9526.3533.4916.8320.8825.3230.89

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