Expression

 

Positive expression of a PDG in a given cancer type was defined as its mRNA expression was reliably detected in at least 50% of tumor specimens (i.e., the 50th percentile of fragments per kilobase of transcript per million mapped reads [FPKM] value ≥1).

 

Summary of PDG mRNA expression levels (FPKM value) in each cancer type


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HGNC Ensembl No. Detectable ACCBLCABRCACESCCHOLCOADDLBCESCAGBMHNSCKICHKIRCKIRPLAMLLGGLIHCLUADLUSCMESOOVPAADPCPGPRADREADSARCSKCMSTADTGCTTHCATHYMUCECUCSUVM
SymbolGene IDCancer Types25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th25th50th75th90th
CATENSG000001216913318.8829.3444.2157.6420.7430.6146.0268.0726.5335.2147.5261.0812.4219.0627.738.4631.5342.2953.8864.8831.1240.551.9566.5222.0327.7436.0941.6716.8624.9336.1750.4326.5232.4837.3345.5512.7618.7725.131.689.51141.6190.45275.3150.9469.7692.12118.5840.1149.5770.0891.22138.44232.48364.66614.4522.1326.6332.7537.986.95133.95197.05262.1626.0337.5154.2973.7420.9828.3140.3954.6914.5818.2722.3528.4625.253346.4760.0225.6132.2739.3751.165.79.3413.6721.8835.0245.253.9363.3132.8140.4349.260.7618.6726.3635.846.516.0623.2734.0248.2827.2437.815066.497.5610.6513.5919.2475.18100.9138.44167.5939.1653.567.1778.4521.1131.9450.6766.6916.6325.9237.3449.178.7712.2919.0628.49
LOXENSG00000113083270.741.372.844.351.153.037.2912.315.2510.1217.9726.933.267.2514.8631.021.012.283.344.831.823.566.8310.920.531.312.285.063.686.6116.3824.283.647.0616.0835.23.768.2916.9433.080.591.383.436.1218.1143.4284.37152.430.551.1637.220.180.290.693.020.340.480.721.680.420.821.884.643.526.0210.821.584.798.9716.5326.7816.4827.5449.1981.641.784.6711.5819.745.5110.9218.2629.660.610.861.292.441.542.594.959.211.963.736.1412.656.4314.7736.4573.71.362.715.1612.733.216.3112.0217.920.541.275.5116.41.112.936.7813.070.310.741.482.941.3636.9716.755.689.7317.4434.030.410.761.844.7
PLK4ENSG00000142731281.42.413.775.3546.328.8611.942.714.426.829.897.1810.4514.0118.261.422.043.215.234.536.357.819.686.238.3710.9214.694.486.268.911.82.363.645.427.123.975.728.3511.740.640.791.161.70.931.251.682.260.650.91.31.816.689.9513.0516.930.881.242.023.730.530.971.843.321.813.044.837.43.845.517.339.641.522.33.244.652.533.665.458.081.462.072.93.850.550.821.111.730.7311.391.923.925.748.1410.152.544.767.5810.962.43.715.737.72.914.496.68.747.29.2511.3612.7711.321.732.083.218.414.2318.814.687.1710.0514.076.117.128.5410.320.551.031.592.23
SPHK1ENSG00000176170320.71.292.7614.493.679.5126.2453.27.2411.9919.4428.6714.8723.5639.5765.075.2220.1155.7881.932.194.7910.0116.257.412.9328.4244.576.4615.0826.6538.443.66.2510.9417.7722.4733.953.0878.80.620.951.822.871.622.614.737.9849.4721.7935.4911.813.185.141.752.894.718.610.82.429.1737.953.436.1612.1918.1511.7817.9528.6443.715.5611.2521.6835.731.73.356.4810.2513.3320.0132.3644.760.811.332.55.841.462.133.325.172.353.837.8312.775.2915.1546.4294.056.2211.5923.5643.454.056.811.8718.475.638.7313.16216.0810.6214.7820.172.687.8714.7223.662.253.596.7312.043.87.2916.125.752.876.1713.4819.97
ALKENSG0000017109450.020.050.150.510.010.020.060.130.030.060.130.280.010.030.080.2200.020.090.1400.010.040.10.010.030.080.240.010.030.070.160.551.062.314.140.010.030.070.150.010.030.080.180.030.070.140.320.020.070.210.570.030.130.280.480.561.072.514.5500.010.020.040.050.120.220.450.060.140.280.650.030.190.731.250.150.431.12.660.050.090.160.290.561.43.125.910.020.040.070.1200.020.040.080.020.050.21.050.411.012.255.070.010.030.080.160.070.150.270.430.260.531.031.880.030.070.140.270.030.090.280.90.10.280.661.250.741.94.5611.38
SERPINE2ENSG00000135919338.3923.7957.96170.012.055.7415.2540.958.9515.6726.2146.552.997.7121.8644.2711.129.8492.43140.1421.8540.0361.6385.122.494.5614.1322.517.4416.2241.0885.896287.25121.55170.4316.0835.7278.87145.740.911.793.568.3126.7344.5576.42150.6891.82168.34309.35551.050.421.112.8911.23106.56142.44181.68230.771.714.8912.1927.335.129.4917.0730.3917.2333.3161.32104.7513.2238.2176.89141.045.1912.0927.9554.8212.8425.5145.3475.6116.0539.4478.06123.892.714.016.028.9926.3950.3375.75100.3110.8927.9875.53138.82322.42705.251475.512799.78714.1226.9749.2420.935.9761.07107.948.1116.6426.5542.256.091116.5634.184.8913.0332.8660.2323.3736.8360.5393.7567.62108.66173.06249.69
PRAMEENSG00000185686120.010.155.3130.230.010.093.6117.430.050.2311.3941.230.040.147.7823.810.070.4113.9823.090.050.321.664.570.140.8815.0440.750.132.8310.4921.930.070.110.20.60.040.8810.426.1900.010.110.490.171.848.1218.071.346.512.518.450.090.414.9644.2200.010.040.0700.031.1515.760.081.31131.428.6421.4642.4984.620.010.040.261.916.939.0861.6593.50.020.070.612.52000.020.080.020.070.332.020.050.141.64.7900.060.4325.02114.71220.28327.33415.180.050.534.612.780.6422.4120.73247.2800.010.030.080.175.6927.2252.4957.94109.97172.03220.6385.47123.66167.2236.820.354.0593.03272.05
ABCB1ENSG000000855632318.848.9497.85163.90.470.921.492.240.71.172.263.530.510.881.572.481.917.2143.9575.573.019.1322.1333.771.1523.035.360.4811.872.964.216.6110.0812.650.330.621.031.690.280.450.711.364.4810.9618.0427.3423.5453.8392.02140.680.831.836.3715.037.099.2612.6716.139.872032.1847.850.651.041.642.40.410.671.021.71.262.414.7310.920.310.470.7312.474.948.9917.7617.5227.5339.6757.122.153.295.176.854.9912.0920.3336.860.611.172.344.340.530.991.943.5811.753.264.990.741.32.263.761.151.792.973.930.791.321.932.660.81.462.273.690.510.771.422.590.250.380.680.96
SLC7A5ENSG00000103257331.472.817.3714.5614.5333.1568.78133.356.9415.9933.7365.7119.6942.4580.77199.163.287.3612.0520.9826.6640.0263.485.5613.8924.2430.2858.8331.8667.23145.99263.0430.4444.8458.7674.6671.14127.54197.47291.031.062.044.5110.73.758.6919.1237.782.924.548.419.169.8517.9429.2547.7339.7553.0968.6987.341.383.136.0810.311.2620.2134.9469.8331.2461.46103.15163.54.4610.0619.1832.145.819.6417.0325.367.8612.1620.0832.553.876.5415.2231.291.452.54.528.0923.3240.556.177.613.728.0913.9224.2961.9129.46244.28371.5212.9524.3344.0764.7618.3230.1546.9371.291.42.34.067.434.176.287.811010.7220.7240.9360.0810.0113.923.334.24201.46284.32352.58515.85
GPER1ENSG00000164850160.72210.6720.30.220.410.791.420.540.951.693.980.380.771.573.580.420.992.192.860.30.541.011.840.591.124.819.440.420.761.432.43.374.565.938.240.450.861.532.60.420.691.191.624.768.8514.1922.642.967.1312.7920.630.350.520.821.53.084.165.477.182.915.6610.2317.060.430.731.312.470.320.570.961.682.164.37.079.930.440.721.21.970.841.2823.070.450.741.633.511.252.343.716.470.290.551.211.921.022.334.559.190.511.092.144.10.310.661.63.60.360.551.011.952.384.017.4611.630.921.42.767.770.560.991.753.740.881.613.26.262.585.497.299.97
POLEENSG00000177084336.439.1812.7719.5112.7118.5825.535.657.8611.115.8222.0522.1628.8238.3747.1110.2414.4818.8327.0811.0514.8619.9226.1516.8225.5434.7421114.9820.3625.944.97.7812.2416.267.1910.4714.9722.832.673.334.146.533.545.037.059.955.027.7211.7615.9134.5449.9371.2493.923.394.957.7411.236.999.3613.8521.385.858.8112.9419.248.0412.6818.9725.327.0810.3813.8617.886.328.9213.5218.535.076.869.7813.722.543.335.077.427.349.9113.0116.8910.7614.5517.5822.459.2414.3620.8928.947.6410.6714.9320.368.0511.0914.8119.4639.5954.5274.9394.923.314.245.627.2216.635.3456.4369.9613.7720.6529.1242.1615.8322.3831.0442.254.97.3910.3612.36
MMP3ENSG0000014996810000.040.110.311.735.714.321.854.499.8519.530.933.4311.8433.1700.050.150.442.829.931.4767.1200.040.514.92.378.323.0465.660.030.150.440.936.3722.577.99155.03000.020.100.020.090.3000.010.15000000.020.110.27000.060.380.120.411.113.120.682.238.1117.290.190.763.4511.8900.020.150.480.621.112.386.63000.010.070.030.10.260.623.1612.8134.88107.330.010.130.74.220.040.231.255.490.673.3217.2444.14000.050.3500.010.10.310.020.190.52.580.170.481.6450.040.250.892.16000.010.05
LMNAENSG0000016078933103.89147.89206.9251.72168.24227.83309.96426.08115.42163.88222.07314.01201.47263.43351.09425.73181.96223.15280.25359.03135.52177.79225.15286.1942.4657.5493.9134.38147.43196.64256328.7946.6367.4990.06124.07261.52332.26418498.3234.5343.945477.3389.07113.46148.58197.79105.68131.75166.52199.8712.526.9966.02135.3927.4337.4454.9880.8113.07157.08214.31298.27137.79182.23235.13311.99132.98178.69231.64298.14206.67299.58376.43512.7486.88119.37167.35226.73189.69251.46313.39386.17107.53145.35210.1279.9660.7580.18108.18157.84129.62172.05207.98246.35202.55279.47409.68616.05292.74416.39572.25806.45116164.55210.17270.1830.0963.1117.27152.25163.87215.72267.3323.1175.53114.82154.16190.8887.85135.23190.76255.47121.04161.54250.16356.2386.63468.4613.79758.3
NFKBIAENSG000001009063352.9991.22128.69167.5967.3496.04151.56223.4356.7576.46100.7133.0582.31114.09159.36219.7484.69112.44156.09188.3440.2653.5470.7889.89110.47148.42183.9230.3154.2781.65120.75219.1549.1571.4489.46122.0884.17112.99167.6232.5624.723142.7777.6176.73107.03151.9194.2350.1365.888.92112.5256.2476.92110.89206.0653.8980.62107.34136.649.5968.6791.28120.4492.15130.63197.66295.8373.61103.25155.11233.6855.8277.99108.83160.8566.5696.14136.86178.0265.3887.22114.76141.9342.5463.387.54113.8757.8571.6188.3711436.3646.5661.2981.2343.0568.26101.67159.1321.2132.095173.7654.5477.66103.97140.2550.4164.4984.29105.0741.5658.280.35105.9587.87130.58172.98253.0453.0978.4113.4174.8331.2852.1973.3393.729.9812.7216.7924.79
JAK3ENSG00000105639281.525.179.9212.591.482.394.358.0611.793.275.671.592.684.717.61.773.75.017.071.192.053.084.0527.3832.7646.0363.711.562.925.348.240.851.632.974.341.282.344.396.990.280.540.91.252.794.627.211.371.693.295.368.0619.0632.8948.4764.060.370.631.242.40.360.821.873.592.974.256.829.912.043.336.1610.342.343.3957.091.792.834.516.622.593.95.778.440.490.821.352.490.641.011.62.561.211.812.763.930.912.455.8811.11.63.236.9412.462.313.796.7711.33.295.649.815.161.273.094.837.095.377.9913.0520.331.312.724.848.592.093.987.8211.480.370.621.322.24
AGR2ENSG0000010654118000.050.1715.2169.08213.51433.2675.88273.31634.561233.895.7534.49176.39824.470.151.6816.32127.49261.48494.22981.471722.6400.070.290.975.8385.03627.061581.55000.050.122.297.1821.8764.2700.060.260.550.010.060.271.110.050.312.18.6100.090.391.5500.010.080.240.020.151.4620.36135.62314.21593.64994.9712.0436.1490.34201.670.030.152.0414.021.153.399.5932.59147.68331.07621.9985.88000.030.1142.33305.2495.03686.49207.5369.41594.41077.7700.030.20.8400.030.150.46326.99780.61588.862590.190.080.254.270.9114.6429.0761.1100.560.41.084.177.978.9336.56154.36356.441.3910.730.0599.530000.09
MMP10ENSG000001666701100.020.060.310.251.217.7131.760.260.822.47.080.62.8516.0366.890.370.881.886.020.391.062.534.980.030.070.20.490.862.99.8141.060.030.10.220.525.0226.7890.77251.310.010.020.060.250.010.050.10.22000.020.06000000.010.040.120.010.050.230.850.220.712.578.642.1211.3156.89210.090.010.040.180.860.080.321.397.030.922.655.9910.7700.010.040.131.092.375.210.220.471.463.839.150.020.10.291.20.020.070.311.110.270.882.557.2400.040.240.80.010.050.150.370.020.060.241.550.412.0511.8148.080.411.344.7717.33000.010.04
RAF1ENSG000001321553320.2823.6930.4237.4531.1339.5551.7671.0630.743641.5549.9125.734.8344.0850.8517.6822.5427.1835.0526.4729.7533.7436.5919.5928.9637.9743.0326.2332.0737.9245.9837.1344.1852.0761.2521.8625.730.7141.0326.6637.8650.8960.3821.2624.4528.0732.4923.1529.2335.7942.0263.8572.4378.2888.6835.2642.6350.1256.6225.7733.4143.2253.0428.9233.7138.6447.1725.8129.934.6642.6226.4231.9636.9244.322.2128.8136.4444.2225.4129.6533.6737.4412.5715.5719.0422.6735.4840.845.4351.4125.6928.7833.7339.7731.8540.4950.1860.726.6633.6139.8245.1922.5928.1833.3838.6943.7153.7764.9776.4733.1838.5242.1946.6532.9240.0847.6754.7825.5534.8842.4949.5230.8438.6147.6255.2715.3920.231.1736.98
TRIOENSG00000038382337.499.6612.6415.711.1715.812330.4415.5721.212732.939.8614.3719.6727.0214.817.0820.2526.514.9418.4922.2928.264.327.0912.9723.2514.6321.0330.0243.5227.0943.6479.57124.1310.6814.2119.6527.356.58.179.5911.7615.4219.3623.969.2612.4815.8721.2832.3241.8358.8669.8621.930.1443.3868.274.686.599.3612.9615.4722.5432.5448.7915.3422.0830.9143.0516.419.7325.5333.899.8113.718.1824.1515.420.8526.630.5217.9522.4528.4537.4411.113.2415.4518.214.4617.3322.6629.3620.1428.6945.8181.678.0411.1617.0825.9810.414.9320.4126.756.838.8712.1520.475.26.648.4910.559.4813.7217.9425.96912.1216.7222.9918.123.7636.0955.26.698.9513.1616.86
PI3ENSG00000124102180.050.150.947.911.086.0992.21745.230.10.452.2214.2832.7222.24908.212523.592.9515.3547.4189.1618.3556.6192.44512.320.080.210.753.1346.8285.781195.773380.480.633.4231.04113.53288.871198.364294.589569.780.060.170.410.840.10.281.46.020.582.57.3321.33000.150.990.030.080.1910.090.624.7514.510.762.127.8329.5415.25109.26450.331674.720.482.5911.638.468.4427.291.98202.611.7335.4596.74199.700.050.140.251.033.247.9519.8630.1382.66377.28647.80.050.221.9112.710.120.543.4165.0812.0569.73301.14802.2500.10.571.880.010.090.250.690.050.21.176.783.6819.8364.41199.763.059.937.8185.5800.040.090.16

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