GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
uromodulin like 1ENSG00000177398UMODL1chr21:42062959-42143453:+68
transient receptor potential cation channel subfamily M member 2ENSG00000142185TRPM2chr21:44350163-44443081:+610.5
somatostatin receptor 3ENSG00000278195SSTR3chr22:37204238-37212322:-79
C-X3-C motif chemokine receptor 1ENSG00000168329CX3CR1chr3:39263494-39281735:-79
glutamate metabotropic receptor 2ENSG00000164082GRM2chr3:51707070-51718613:+79
5-hydroxytryptamine receptor 1FENSG00000179097HTR1Fchr3:87990696-87993835:+79
acid phosphatase 3ENSG00000014257ACPPchr3:132317367-132368298:+610.5
atypical chemokine receptor 4ENSG00000129048ACKR4chr3:132597237-132618967:+79
G protein-coupled receptor 87ENSG00000138271GPR87chr3:151294086-151316952:-68
gamma-aminobutyric acid type A receptor subunit alpha1ENSG00000022355GABRA1chr5:161847191-161899969:+710.5
5-hydroxytryptamine receptor 1EENSG00000168830HTR1Echr6:86937306-87016683:+79
G protein-coupled receptor 6ENSG00000146360GPR6chr6:109978256-109980718:+68
G protein-coupled receptor class C group 6 member AENSG00000173612GPRC6Achr6:116792085-116829037:-79
corticotropin releasing hormone receptor 2ENSG00000106113CRHR2chr7:30651943-30700129:-68
glutamate metabotropic receptor 3ENSG00000198822GRM3chr7:86643914-86864884:+79
G protein-coupled receptor 85ENSG00000164604GPR85chr7:113078331-113087778:-79
taste 2 receptor member 16ENSG00000128519TAS2R16chr7:122994704-122995700:-68
G protein-coupled receptor 37ENSG00000170775GPR37chr7:124745997-124765627:-68
taste 2 receptor member 4ENSG00000127364TAS2R4chr7:141778442-141780819:+68
TNF receptor superfamily member 10cENSG00000173535TNFRSF10Cchr8:23084355-23117437:+79.5

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