GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
uromodulin like 1 | ENSG00000177398 | UMODL1 | chr21:42062959-42143453:+ | 6 | 8 |
transient receptor potential cation channel subfamily M member 2 | ENSG00000142185 | TRPM2 | chr21:44350163-44443081:+ | 6 | 10.5 |
somatostatin receptor 3 | ENSG00000278195 | SSTR3 | chr22:37204238-37212322:- | 7 | 9 |
C-X3-C motif chemokine receptor 1 | ENSG00000168329 | CX3CR1 | chr3:39263494-39281735:- | 7 | 9 |
glutamate metabotropic receptor 2 | ENSG00000164082 | GRM2 | chr3:51707070-51718613:+ | 7 | 9 |
5-hydroxytryptamine receptor 1F | ENSG00000179097 | HTR1F | chr3:87990696-87993835:+ | 7 | 9 |
acid phosphatase 3 | ENSG00000014257 | ACPP | chr3:132317367-132368298:+ | 6 | 10.5 |
atypical chemokine receptor 4 | ENSG00000129048 | ACKR4 | chr3:132597237-132618967:+ | 7 | 9 |
G protein-coupled receptor 87 | ENSG00000138271 | GPR87 | chr3:151294086-151316952:- | 6 | 8 |
gamma-aminobutyric acid type A receptor subunit alpha1 | ENSG00000022355 | GABRA1 | chr5:161847191-161899969:+ | 7 | 10.5 |
5-hydroxytryptamine receptor 1E | ENSG00000168830 | HTR1E | chr6:86937306-87016683:+ | 7 | 9 |
G protein-coupled receptor 6 | ENSG00000146360 | GPR6 | chr6:109978256-109980718:+ | 6 | 8 |
G protein-coupled receptor class C group 6 member A | ENSG00000173612 | GPRC6A | chr6:116792085-116829037:- | 7 | 9 |
corticotropin releasing hormone receptor 2 | ENSG00000106113 | CRHR2 | chr7:30651943-30700129:- | 6 | 8 |
glutamate metabotropic receptor 3 | ENSG00000198822 | GRM3 | chr7:86643914-86864884:+ | 7 | 9 |
G protein-coupled receptor 85 | ENSG00000164604 | GPR85 | chr7:113078331-113087778:- | 7 | 9 |
taste 2 receptor member 16 | ENSG00000128519 | TAS2R16 | chr7:122994704-122995700:- | 6 | 8 |
G protein-coupled receptor 37 | ENSG00000170775 | GPR37 | chr7:124745997-124765627:- | 6 | 8 |
taste 2 receptor member 4 | ENSG00000127364 | TAS2R4 | chr7:141778442-141780819:+ | 6 | 8 |
TNF receptor superfamily member 10c | ENSG00000173535 | TNFRSF10C | chr8:23084355-23117437:+ | 7 | 9.5 |
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