GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
MAS related GPR family member D | ENSG00000172938 | MRGPRD | chr11:68980021-68980986:- | 6 | 8 |
olfactory receptor family 10 subfamily D member 3 (putative) | ENSG00000197309 | OR10D3 | chr11:124185216-124186245:+ | 6 | 8 |
olfactory receptor family 8 subfamily B member 4 (gene/pseudogene) | ENSG00000280090 | OR8B4 | chr11:124423904-124424893:- | 6 | 8 |
taste 2 receptor member 46 | ENSG00000226761 | TAS2R46 | chr12:11061365-11062294:- | 6 | 8 |
G protein-coupled receptor class C group 5 member D | ENSG00000111291 | GPRC5D | chr12:12940775-12952147:- | 7 | 9 |
frizzled class receptor 10 | ENSG00000111432 | FZD10 | chr12:130162459-130165740:+ | 7 | 9 |
G protein-coupled receptor 12 | ENSG00000132975 | GPR12 | chr13:26755200-26760785:- | 6 | 8 |
G protein-coupled receptor 18 | ENSG00000125245 | GPR18 | chr13:99254714-99261744:- | 7 | 9 |
glutamate ionotropic receptor NMDA type subunit 2A | ENSG00000183454 | GRIN2A | chr16:9753404-10182754:- | 7 | 9.5 |
G protein-coupled receptor class C group 5 member B | ENSG00000167191 | GPRC5B | chr16:19856691-19886167:- | 7 | 12 |
olfactory receptor family 4 subfamily D member 2 | ENSG00000255713 | OR4D2 | chr17:58169656-58170579:+ | 6 | 7.5 |
adhesion G protein-coupled receptor E1 | ENSG00000174837 | ADGRE1 | chr19:6887566-6940459:+ | 7 | 9 |
adhesion G protein-coupled receptor L1 | ENSG00000072071 | ADGRL1 | chr19:14147743-14206187:- | 7 | 10 |
lysophosphatidic acid receptor 2 | ENSG00000064547 | LPAR2 | chr19:19623668-19628930:- | 6 | 8 |
formyl peptide receptor 2 | ENSG00000171049 | FPR2 | chr19:51752026-51770526:+ | 6 | 8 |
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 | ENSG00000189013 | KIR2DL4 | chr19:54803535-54814517:+ | 6 | 8 |
glycoprotein VI platelet | ENSG00000088053 | GP6 | chr19:55013705-55038264:- | 6 | 7.5 |
trans-golgi network protein 2 | ENSG00000152291 | TGOLN2 | chr2:85318020-85328425:- | 7 | 12 |
lactase | ENSG00000115850 | LCT | chr2:135787840-135837180:- | 6 | 8.5 |
potassium voltage-gated channel subfamily E regulatory subunit 1 | ENSG00000180509 | KCNE1 | chr21:34446688-34512275:- | 7 | 9.5 |
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