GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
vomeronasal 1 receptor 1ENSG00000178201VN1R1chr19:57454790-57457142:-68
neurotensin receptor 2ENSG00000169006NTSR2chr2:11658178-11670164:-68
secretin receptorENSG00000080293SCTRchr2:119439843-119525301:-68
G protein-coupled receptor 17ENSG00000144230GPR17chr2:127645864-127652639:+79
parathyroid hormone 2 receptorENSG00000144407PTH2Rchr2:208359714-208854503:+68
histamine receptor H3ENSG00000101180HRH3chr20:62214970-62220267:-79
neuropeptides B and W receptor 2ENSG00000125522NPBWR2chr20:64105820-64107171:-79
olfactory receptor family 11 subfamily H member 1ENSG00000130538OR11H1chr22:15528158-15529139:+68
atypical chemokine receptor 2ENSG00000144648ACKR2chr3:42804752-42887974:+79
olfactory receptor family 5 subfamily AC member 2ENSG00000196578OR5AC2chr3:98087173-98088102:+68
olfactory receptor family 5 subfamily H member 14ENSG00000236032OR5H14chr3:98149326-98150405:+68
olfactory receptor family 5 subfamily H member 6 (gene/pseudogene)ENSG00000230301OR5H6chr3:98264285-98265262:+68
olfactory receptor family 5 subfamily H member 2ENSG00000197938OR5H2chr3:98282888-98283832:+68
olfactory receptor family 5 subfamily K member 4ENSG00000196098OR5K4chr3:98353854-98354819:+68
G protein-coupled receptor 78ENSG00000155269GPR78chr4:8558725-8619761:+68
gonadotropin releasing hormone receptorENSG00000109163GNRHRchr4:67739328-67754360:-79
tachykinin receptor 3ENSG00000169836TACR3chr4:103586031-103719816:-79
relaxin family peptide receptor 3ENSG00000182631RXFP3chr5:33936386-33938237:+79
G protein-coupled receptor 150ENSG00000178015GPR150chr5:95620078-95622142:+79
histamine receptor H2ENSG00000113749HRH2chr5:175658030-175686242:+79

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