GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
solute carrier family 1 member 1ENSG00000106688SLC1A1chr9:4490444-4587469:+78.5
solute carrier family 28 member 3ENSG00000197506SLC28A3chr9:84275457-84340683:-89.5
glutamate ionotropic receptor NMDA type subunit 3AENSG00000198785GRIN3Achr9:101569353-101738580:-89.5
glycine receptor alpha 2ENSG00000101958GLRA2chrX:14529298-14731812:+89.5
patched domain containing 1ENSG00000165186PTCHD1chrX:23334015-23404372:+78.5
solute carrier family 38 member 5ENSG00000017483SLC38A5chrX:48458537-48470256:-811.5
solute carrier family 7 member 3ENSG00000165349SLC7A3chrX:70925582-70931125:-78.5
gamma-aminobutyric acid type A receptor subunit epsilonENSG00000102287GABREchrX:151953124-151974680:-89.5
gamma-aminobutyric acid type A receptor subunit alpha3ENSG00000011677GABRA3chrX:152166234-152451358:-89.5
chromosome 1 open reading frame 159ENSG00000131591C1orf159chr1:1081818-1116361:-710.5
cache domain containing 1ENSG00000158966CACHD1chr1:64470792-64693058:+810.5
phospholipid phosphatase related 5ENSG00000117598LPPR5chr1:98890245-99005032:-89.5
potassium voltage-gated channel subfamily A member 2ENSG00000177301KCNA2chr1:110593580-110631474:-89.5
gap junction protein alpha 5ENSG00000265107GJA5chr1:147756199-147773362:-89.5
synaptic vesicle glycoprotein 2AENSG00000159164SV2Achr1:149903318-149917882:-811.5
ADAM metallopeptidase domain 15ENSG00000143537ADAM15chr1:155050566-155062775:+712.5
SLAM family member 7ENSG00000026751SLAMF7chr1:160739057-160754821:+79.5
TNF superfamily member 4ENSG00000117586TNFSF4chr1:173183734-173207313:-78.5
potassium voltage-gated channel subfamily C member 1ENSG00000129159KCNC1chr11:17734812-17783055:+89.5
glycerophosphodiester phosphodiesterase domain containing 5ENSG00000158555GDPD5chr11:75434640-75525903:-712

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