GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1ENSG00000167633KIR3DL1chr19:54724497-54867215:+1213.5
ANTXR cell adhesion molecule 1ENSG00000169604ANTXR1chr2:69013178-69249327:+1315.5
interleukin 1 receptor type 2ENSG00000115590IL1R2chr2:101991844-102028544:+1214.5
dipeptidyl peptidase 4ENSG00000197635DPP4chr2:161992241-162074542:-1218.5
bone morphogenetic protein receptor type 2ENSG00000204217BMPR2chr2:202376936-202567751:+1317.5
delta/notch like EGF repeat containingENSG00000187957DNERchr2:229357629-229714558:-1214.5
CXADR Ig-like cell adhesion moleculeENSG00000154639CXADRchr21:17512382-17593579:+1217.5
interferon alpha and beta receptor subunit 2ENSG00000159110IFNAR2chr21:33229901-33265675:+1316.5
inducible T cell costimulator ligandENSG00000160223ICOSLGchr21:44222991-44240966:-1318.5
interleukin 17 receptor AENSG00000177663IL17RAchr22:17084954-17115694:+1217.5
interleukin 2 receptor subunit betaENSG00000100385IL2RBchr22:37125838-37175054:-1214.5
dystroglycan 1ENSG00000173402DAG1chr3:49468703-49535618:+1220.5
activated leukocyte cell adhesion moleculeENSG00000170017ALCAMchr3:105366909-105576900:+1220.5
CD200 receptor 1ENSG00000163606CD200R1chr3:112921209-112975122:-1215.5
EPH receptor B1ENSG00000154928EPHB1chr3:134597801-135260467:+1316.5
membrane metalloendopeptidaseENSG00000196549MMEchr3:155024124-155183729:+1217.5
mucin 4, cell surface associatedENSG00000145113MUC4chr3:195746765-195812277:-1213.5
toll like receptor 1ENSG00000174125TLR1chr4:38790677-38856817:-1315.5
sarcoglycan betaENSG00000163069SGCBchr4:52020706-52038482:-1315.5
platelet derived growth factor receptor alphaENSG00000134853PDGFRAchr4:54229097-54298247:+1315.5

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