GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 | ENSG00000167633 | KIR3DL1 | chr19:54724497-54867215:+ | 12 | 13.5 |
ANTXR cell adhesion molecule 1 | ENSG00000169604 | ANTXR1 | chr2:69013178-69249327:+ | 13 | 15.5 |
interleukin 1 receptor type 2 | ENSG00000115590 | IL1R2 | chr2:101991844-102028544:+ | 12 | 14.5 |
dipeptidyl peptidase 4 | ENSG00000197635 | DPP4 | chr2:161992241-162074542:- | 12 | 18.5 |
bone morphogenetic protein receptor type 2 | ENSG00000204217 | BMPR2 | chr2:202376936-202567751:+ | 13 | 17.5 |
delta/notch like EGF repeat containing | ENSG00000187957 | DNER | chr2:229357629-229714558:- | 12 | 14.5 |
CXADR Ig-like cell adhesion molecule | ENSG00000154639 | CXADR | chr21:17512382-17593579:+ | 12 | 17.5 |
interferon alpha and beta receptor subunit 2 | ENSG00000159110 | IFNAR2 | chr21:33229901-33265675:+ | 13 | 16.5 |
inducible T cell costimulator ligand | ENSG00000160223 | ICOSLG | chr21:44222991-44240966:- | 13 | 18.5 |
interleukin 17 receptor A | ENSG00000177663 | IL17RA | chr22:17084954-17115694:+ | 12 | 17.5 |
interleukin 2 receptor subunit beta | ENSG00000100385 | IL2RB | chr22:37125838-37175054:- | 12 | 14.5 |
dystroglycan 1 | ENSG00000173402 | DAG1 | chr3:49468703-49535618:+ | 12 | 20.5 |
activated leukocyte cell adhesion molecule | ENSG00000170017 | ALCAM | chr3:105366909-105576900:+ | 12 | 20.5 |
CD200 receptor 1 | ENSG00000163606 | CD200R1 | chr3:112921209-112975122:- | 12 | 15.5 |
EPH receptor B1 | ENSG00000154928 | EPHB1 | chr3:134597801-135260467:+ | 13 | 16.5 |
membrane metalloendopeptidase | ENSG00000196549 | MME | chr3:155024124-155183729:+ | 12 | 17.5 |
mucin 4, cell surface associated | ENSG00000145113 | MUC4 | chr3:195746765-195812277:- | 12 | 13.5 |
toll like receptor 1 | ENSG00000174125 | TLR1 | chr4:38790677-38856817:- | 13 | 15.5 |
sarcoglycan beta | ENSG00000163069 | SGCB | chr4:52020706-52038482:- | 13 | 15.5 |
platelet derived growth factor receptor alpha | ENSG00000134853 | PDGFRA | chr4:54229097-54298247:+ | 13 | 15.5 |
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