GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
solute carrier family 16 member 12ENSG00000152779SLC16A12chr10:89430299-89556641:-89.5
oligodendrocytic myelin paranodal and inner loop proteinENSG00000197430OPALINchr10:96343216-96359365:-89.5
calcyon neuron specific vesicular proteinENSG00000130643CALYchr10:133324072-133336935:-89.5
olfactory receptor family 52 subfamily J member 3ENSG00000205495OR52J3chr11:5046526-5047461:+89.5
olfactory receptor family 4 subfamily C member 5 (gene/pseudogene)ENSG00000176540OR4C5chr11:48365485-48366465:-78.5
potassium voltage-gated channel subfamily E regulatory subunit 3ENSG00000175538KCNE3chr11:74454841-74467729:-810.5
calcium voltage-gated channel subunit alpha1 CENSG00000151067CACNA1Cchr12:1970786-2697950:+711
killer cell lectin like receptor F2ENSG00000256797KLRF2chr12:9881489-9895833:+78.5
glutamate ionotropic receptor NMDA type subunit 2BENSG00000273079GRIN2Bchr12:13537337-13981957:-810.5
activin A receptor like type 1ENSG00000139567ACVRL1chr12:51906908-51923361:+810.5
olfactory receptor family 10 subfamily A member 7ENSG00000179919OR10A7chr12:55221025-55221975:+78.5
TNF superfamily member 11ENSG00000120659TNFSF11chr13:42562736-42608013:+78.5
protocadherin 8ENSG00000136099PCDH8chr13:52842889-52848641:-89.5
ATPase H+/K+ transporting subunit betaENSG00000186009ATP4Bchr13:113648804-113658186:-89.5
amnion associated transmembrane proteinENSG00000166126AMNchr14:102922656-102933596:+78.5
solute carrier family 51 subunit betaENSG00000186198SLC51Bchr15:65045370-65053396:+78.5
solute carrier family 52 member 1ENSG00000132517SLC52A1chr17:5032600-5052009:-78.5
tumor protein p53 inducible protein 13ENSG00000167543TP53I13chr17:29566052-29573157:+78.5
plexin domain containing 1ENSG00000161381PLXDC1chr17:39063303-39154394:-79.5
ring finger protein 43ENSG00000108375RNF43chr17:58352500-58417595:-810.5

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