GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
olfactory receptor family 1 subfamily L member 4ENSG00000136939OR1L4chr9:122723990-122724925:+79
olfactory receptor family 1 subfamily L member 6ENSG00000171459OR1L6chr9:122749740-122750783:+79
olfactory receptor family 5 subfamily C member 1ENSG00000148215OR5C1chr9:122788933-122789895:+79
G protein-coupled receptor 21ENSG00000188394GPR21chr9:123034527-123035696:+79
glutamate ionotropic receptor NMDA type subunit 1ENSG00000176884GRIN1chr9:137138390-137168762:+811.5
G protein-coupled receptor 143ENSG00000101850GPR143chrX:9725346-9786297:-79
pyrimidinergic receptor P2Y4ENSG00000186912P2RY4chrX:70258170-70259764:-79
olfactory receptor family 13 subfamily H member 1ENSG00000171054OR13H1chrX:131544074-131545000:+79
bombesin receptor subtype 3ENSG00000102239BRS3chrX:136487887-136493780:+810
G protein-coupled receptor 101ENSG00000165370GPR101chrX:137030148-137031674:-810
opsin 1, medium wave sensitiveENSG00000268221OPN1MWchrX:154182596-154196135:+810
TNF receptor superfamily member 18ENSG00000186891TNFRSF18chr1:1203508-1206691:-78.5
adherens junctions associated protein 1ENSG00000196581AJAP1chr1:4654732-4792534:+89.5
leucine rich repeat containing 38ENSG00000162494LRRC38chr1:13474977-13514048:-810.5
protein tyrosine phosphatase receptor type UENSG00000060656PTPRUchr1:29236516-29326813:+78.5
erythroblast membrane associated protein (Scianna blood group)ENSG00000164010ERMAPchr1:42817124-42844989:+89.5
selectin EENSG00000007908SELEchr1:169722641-169764705:-78.5
crumbs cell polarity complex component 1ENSG00000134376CRB1chr1:197268204-197478455:+810.5
toll like receptor 5ENSG00000187554TLR5chr1:223109406-223143282:-89.5
potassium calcium-activated channel subfamily M alpha 1ENSG00000156113KCNMA1chr10:76869601-77638595:-813.5

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