GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
stromal interaction molecule 1 | ENSG00000167323 | STIM1 | chr11:3854527-4093210:+ | 13 | 18.5 |
protein tyrosine phosphatase receptor type J | ENSG00000149177 | PTPRJ | chr11:47980558-48170841:+ | 12 | 19.5 |
nectin cell adhesion molecule 1 | ENSG00000110400 | PVRL1 | chr11:119623408-119729084:- | 13 | 17.5 |
junctional adhesion molecule 3 | ENSG00000166086 | JAM3 | chr11:134068925-134152001:+ | 12 | 18.5 |
KIT ligand | ENSG00000049130 | KITLG | chr12:88492793-88580851:- | 12 | 14.5 |
integral membrane protein 2B | ENSG00000136156 | ITM2B | chr13:48233158-48270357:+ | 13 | 16.5 |
ephrin B2 | ENSG00000125266 | EFNB2 | chr13:106489731-106535114:- | 13 | 19.5 |
insulin like growth factor 1 receptor | ENSG00000140443 | IGF1R | chr15:98648971-98964530:+ | 13 | 20.5 |
integrin subunit alpha L | ENSG00000005844 | ITGAL | chr16:30472658-30523185:+ | 12 | 17.5 |
integrin subunit alpha M | ENSG00000169896 | ITGAM | chr16:31259990-31332892:+ | 12 | 16.5 |
cadherin 3 | ENSG00000062038 | CDH3 | chr16:68636189-68722616:+ | 13 | 16.5 |
CD68 molecule | ENSG00000129226 | CD68 | chr17:7579467-7582113:+ | 12 | 14.5 |
ATPase Na+/K+ transporting subunit beta 2 | ENSG00000129244 | ATP1B2 | chr17:7646627-7657768:+ | 13 | 14.5 |
integrin subunit alpha 3 | ENSG00000005884 | ITGA3 | chr17:50055968-50090481:+ | 12 | 19.5 |
CD79b molecule | ENSG00000007312 | CD79B | chr17:63928740-63932354:- | 13 | 16.5 |
basigin (Ok blood group) | ENSG00000172270 | BSG | chr19:571277-583493:+ | 13 | 21.5 |
bone marrow stromal cell antigen 2 | ENSG00000130303 | BST2 | chr19:17402939-17405648:- | 13 | 20.5 |
CEA cell adhesion molecule 1 | ENSG00000079385 | CEACAM1 | chr19:42507304-42561234:- | 12 | 15.5 |
CD33 molecule | ENSG00000105383 | CD33 | chr19:51225064-51243860:+ | 12 | 15.5 |
sialic acid binding Ig like lectin 10 | ENSG00000142512 | SIGLEC10 | chr19:51410021-51417803:- | 12 | 15.5 |
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