GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
interleukin 1 receptor accessory protein | ENSG00000196083 | IL1RAP | chr3:190514051-190659750:+ | 12 | 20 |
protocadherin 7 | ENSG00000169851 | PCDH7 | chr4:30720415-31146805:+ | 13 | 18 |
fibroblast growth factor receptor 1 | ENSG00000077782 | FGFR1 | chr8:38411138-38468834:- | 13 | 19 |
neuroligin 4 X-linked | ENSG00000146938 | NLGN4X | chrX:5840637-6228863:- | 13 | 17.5 |
TNF receptor superfamily member 8 | ENSG00000120949 | TNFRSF8 | chr1:12063377-12144207:+ | 12 | 16.5 |
endothelin converting enzyme 1 | ENSG00000117298 | ECE1 | chr1:21217247-21345504:- | 12 | 20.5 |
tumor associated calcium signal transducer 2 | ENSG00000184292 | TACSTD2 | chr1:58575423-58577773:- | 12 | 15.5 |
adhesion G protein-coupled receptor L2 | ENSG00000117114 | ADGRL2 | chr1:81306160-81992436:+ | 13 | 21 |
kirre like nephrin family adhesion molecule 1 | ENSG00000183853 | KIRREL | chr1:157993273-158100262:+ | 12 | 17.5 |
CD1d molecule | ENSG00000158473 | CD1D | chr1:158179947-158184896:+ | 13 | 14.5 |
SLAM family member 6 | ENSG00000162739 | SLAMF6 | chr1:160485030-160523262:- | 12 | 15.5 |
lymphocyte antigen 9 | ENSG00000122224 | LY9 | chr1:160796074-160828261:+ | 12 | 15.5 |
CD244 molecule | ENSG00000122223 | CD244 | chr1:160830160-160862855:- | 12 | 15.5 |
Fc fragment of IgG receptor IIIa | ENSG00000203747 | FCGR3A | chr1:161541759-161550737:- | 12 | 13.5 |
selectin P | ENSG00000174175 | SELP | chr1:169588849-169630193:- | 12 | 14.5 |
selectin L | ENSG00000188404 | SELL | chr1:169690667-169711698:- | 12 | 16.5 |
neurofascin | ENSG00000163531 | NFASC | chr1:204828651-205022822:+ | 12 | 16.5 |
mannose receptor C-type 1 | ENSG00000260314 | MRC1 | chr10:17809344-17911170:+ | 12 | 16.5 |
neuropilin 1 | ENSG00000099250 | NRP1 | chr10:33177492-33336262:- | 12 | 18.5 |
ADAM metallopeptidase domain 12 | ENSG00000148848 | ADAM12 | chr10:126012381-126388455:- | 12 | 14.5 |
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