GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
chloride voltage-gated channel 6 | ENSG00000011021 | CLCN6 | chr1:11806096-11843144:+ | 8 | 11.5 |
roundabout guidance receptor 4 | ENSG00000154133 | ROBO4 | chr11:124883691-124898500:- | 9 | 10 |
transmembrane protein 30B | ENSG00000182107 | TMEM30B | chr14:61277370-61281840:- | 9 | 10.5 |
osteoclast associated Ig-like receptor | ENSG00000170909 | OSCAR | chr19:54094668-54102692:- | 8 | 10 |
alkaline phosphatase, biomineralization associated | ENSG00000162551 | ALPL | chr1:21509372-21578412:+ | 8 | 11.5 |
ephrin A1 | ENSG00000169242 | EFNA1 | chr1:155127460-155134857:+ | 9 | 9.5 |
CEA cell adhesion molecule 8 | ENSG00000124469 | CEACAM8 | chr19:42580241-42740384:- | 8 | 9.5 |
alkaline phosphatase, germ cell | ENSG00000163286 | ALPPL2 | chr2:232406843-232410714:+ | 8 | 8.5 |
contactin 3 | ENSG00000113805 | CNTN3 | chr3:74262568-74521140:- | 8 | 10 |
slit guidance ligand 2 | ENSG00000145147 | SLIT2 | chr4:20253260-20620561:+ | 8 | 10 |
glypican 5 | ENSG00000179399 | GPC5 | chr13:91398675-92873682:+ | 8 | 9.5 |
alkaline phosphatase, intestinal | ENSG00000163295 | ALPI | chr2:232456123-232460032:+ | 8 | 8 |
GDNF family receptor alpha 2 | ENSG00000168546 | GFRA2 | chr8:21690403-21812357:- | 9 | 9 |
golgi membrane protein 1 | ENSG00000135052 | GOLM1 | chr9:86026146-86100173:- | 8 | 11 |
C-type lectin domain family 2 member B | ENSG00000110852 | CLEC2B | chr12:9852984-9870136:- | 8 | 12 |
immunoglobulin superfamily containing leucine rich repeat | ENSG00000129009 | ISLR | chr15:74173671-74176872:+ | 8 | 9.5 |
MAM domain containing glycosylphosphatidylinositol anchor 1 | ENSG00000112139 | MDGA1 | chr6:37630679-37699306:- | 8 | 9 |
T cell receptor alpha constant | ENSG00000277734 | TRAC | chr14:22281105-22552155:+ | 8 | 8 |
gamma-glutamyltransferase 3 pseudogene | ENSG00000197421 | GGT3P | chr22:18773665-18843399:- | 9 | 11 |
mucin 20, cell surface associated | ENSG00000176945 | MUC20 | chr3:195720882-195741123:+ | 8 | 9 |
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