GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
chloride voltage-gated channel 6ENSG00000011021CLCN6chr1:11806096-11843144:+811.5
roundabout guidance receptor 4ENSG00000154133ROBO4chr11:124883691-124898500:-910
transmembrane protein 30BENSG00000182107TMEM30Bchr14:61277370-61281840:-910.5
osteoclast associated Ig-like receptorENSG00000170909OSCARchr19:54094668-54102692:-810
alkaline phosphatase, biomineralization associatedENSG00000162551ALPLchr1:21509372-21578412:+811.5
ephrin A1ENSG00000169242EFNA1chr1:155127460-155134857:+99.5
CEA cell adhesion molecule 8ENSG00000124469CEACAM8chr19:42580241-42740384:-89.5
alkaline phosphatase, germ cellENSG00000163286ALPPL2chr2:232406843-232410714:+88.5
contactin 3ENSG00000113805CNTN3chr3:74262568-74521140:-810
slit guidance ligand 2ENSG00000145147SLIT2chr4:20253260-20620561:+810
glypican 5ENSG00000179399GPC5chr13:91398675-92873682:+89.5
alkaline phosphatase, intestinalENSG00000163295ALPIchr2:232456123-232460032:+88
GDNF family receptor alpha 2ENSG00000168546GFRA2chr8:21690403-21812357:-99
golgi membrane protein 1ENSG00000135052GOLM1chr9:86026146-86100173:-811
C-type lectin domain family 2 member BENSG00000110852CLEC2Bchr12:9852984-9870136:-812
immunoglobulin superfamily containing leucine rich repeatENSG00000129009ISLRchr15:74173671-74176872:+89.5
MAM domain containing glycosylphosphatidylinositol anchor 1ENSG00000112139MDGA1chr6:37630679-37699306:-89
T cell receptor alpha constantENSG00000277734TRACchr14:22281105-22552155:+88
gamma-glutamyltransferase 3 pseudogeneENSG00000197421GGT3Pchr22:18773665-18843399:-911
mucin 20, cell surface associatedENSG00000176945MUC20chr3:195720882-195741123:+89

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