GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
macrophage receptor with collagenous structureENSG00000019169MARCOchr2:118942166-118994660:+911
sodium voltage-gated channel alpha subunit 7ENSG00000136546SCN7Achr2:166403573-166494247:-910.5
ATP binding cassette subfamily A member 12ENSG00000144452ABCA12chr2:214931542-215138428:-89.5
glypican 1ENSG00000063660GPC1chr2:240435671-240468078:+815
solute carrier family 6 member 11ENSG00000132164SLC6A11chr3:10816200-10940733:+910.5
toll like receptor 9ENSG00000239732TLR9chr3:52221080-52226163:-911
transmembrane 4 L six family member 4ENSG00000169903TM4SF4chr3:149473974-149503281:+89.5
occludinENSG00000197822OCLNchr5:69492292-69558104:+912.5
solute carrier family 16 member 10ENSG00000112394SLC16A10chr6:111087503-111231194:+810.5
insulin like growth factor 2 receptorENSG00000197081IGF2Rchr6:159969099-160113507:+917.5
sidekick cell adhesion molecule 1ENSG00000146555SDK1chr7:3301448-4269000:+913.5
tetraspanin 13ENSG00000106537TSPAN13chr7:16753535-16784536:+811.5
claudin 23ENSG00000253958CLDN23chr8:8701938-8704106:+910.5
potassium voltage-gated channel subfamily B member 2ENSG00000182674KCNB2chr8:72537391-72938349:+910.5
solute carrier family 45 member 4ENSG00000022567SLC45A4chr8:141207166-141308305:-89.5
proteolipid protein 2ENSG00000102007PLP2chrX:49171926-49175239:+814.5
solute carrier family 6 member 14ENSG00000268104SLC6A14chrX:116436622-116461458:+910.5
teneurin transmembrane protein 1ENSG00000009694TENM1chrX:124375903-124963817:-910.5
glypican 3ENSG00000147257GPC3chrX:133535745-133985895:-89
solute carrier family 6 member 8ENSG00000130821SLC6A8chrX:153688099-153696593:+911.5

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