GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
interleukin 13 receptor subunit alpha 1ENSG00000131724IL13RA1chrX:118727572-118794539:+913.5
SLIT and NTRK like family member 2ENSG00000185985SLITRK2chrX:145817832-145825842:+910.5
tetraspanin 1ENSG00000117472TSPAN1chr1:46175073-46185958:+911.5
solute carrier family 44 member 5ENSG00000137968SLC44A5chr1:75202131-75611116:-89.5
CD151 molecule (Raph blood group)ENSG00000177697CD151chr11:832843-839831:+916.5
LDL receptor related protein 5ENSG00000162337LRP5chr11:68312609-68449275:+911.5
solute carrier family 36 member 4ENSG00000180773SLC36A4chr11:93144171-93197964:-89.5
epithelial membrane protein 1ENSG00000134531EMP1chr12:13196716-13219939:+911.5
solute carrier family 2 member 13ENSG00000151229SLC2A13chr12:39755021-40106089:-913.5
tetraspanin 31ENSG00000135452TSPAN31chr12:57738013-57750211:+811.5
potassium voltage-gated channel subfamily C member 2ENSG00000166006KCNC2chr12:75040077-75209868:-910.5
solute carrier family 6 member 15ENSG00000072041SLC6A15chr12:84859488-84913615:-910.5
solute carrier family 8 member B1ENSG00000089060SLC8B1chr12:113298759-113359493:-810.5
purinergic receptor P2X 1ENSG00000108405P2RX1chr17:3896592-3916500:-911.5
desmoglein 1ENSG00000134760DSG1chr18:31318089-31357029:+915
LY6/PLAUR domain containing 3ENSG00000124466LYPD3chr19:43460787-43465660:-911.5
epithelial membrane protein 3ENSG00000142227EMP3chr19:48321509-48330553:+912.5
leukocyte immunoglobulin like receptor A5ENSG00000187116LILRA5chr19:54307070-54313139:-89
leukocyte immunoglobulin like receptor A1ENSG00000104974LILRA1chr19:54573879-54602090:+811
ST3 beta-galactoside alpha-2,3-sialyltransferase 5ENSG00000115525ST3GAL5chr2:85839144-85889014:-89.5

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