GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
transmembrane 4 L six family member 1ENSG00000169908TM4SF1chr3:149369022-149377865:-810.5
transferrin receptorENSG00000072274TFRCchr3:196027183-196082189:-816.5
scavenger receptor class B member 2ENSG00000138760SCARB2chr4:76158737-76213893:-815.5
bone morphogenetic protein receptor type 1BENSG00000138696BMPR1Bchr4:94757968-95158448:+910.5
unc-5 netrin receptor CENSG00000182168UNC5Cchr4:95162504-95549206:-810.5
teneurin transmembrane protein 3ENSG00000218336TENM3chr4:182143987-182803024:+914.5
semaphorin 5AENSG00000112902SEMA5Achr5:9035026-9546075:-810.5
oncostatin M receptorENSG00000145623OSMRchr5:38845858-38945596:+911.5
family with sequence similarity 174 member AENSG00000174132FAM174Achr5:100535305-100586741:+810.5
glycoprotein integral membrane 1ENSG00000055211GINM1chr6:149566294-149591748:+89.5
retinoic acid early transcript 1GENSG00000203722RAET1Gchr6:149916878-149923121:-911
claudin 3ENSG00000165215CLDN3chr7:73768997-73770270:-911.5
solute carrier family 26 member 3ENSG00000091138SLC26A3chr7:107765467-107803225:-910.5
contactin associated protein 2ENSG00000174469CNTNAP2chr7:146116002-148420998:+89.5
solute carrier family 20 member 2ENSG00000168575SLC20A2chr8:42416475-42541926:-913.5
dendrocyte expressed seven transmembrane proteinENSG00000164935DCSTAMPchr8:104339087-104356689:+89.5
protein tyrosine phosphatase receptor type DENSG00000153707PTPRDchr9:8314246-10612723:-811.5
interleukin 3 receptor subunit alphaENSG00000185291IL3RAchrX:1336616-1382689:+912.5
solute carrier family 16 member 2ENSG00000147100SLC16A2chrX:74421461-74533917:+810.5
claudin 2ENSG00000165376CLDN2chrX:106900164-106930861:+910.5

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