GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
transmembrane 4 L six family member 1 | ENSG00000169908 | TM4SF1 | chr3:149369022-149377865:- | 8 | 10.5 |
transferrin receptor | ENSG00000072274 | TFRC | chr3:196027183-196082189:- | 8 | 16.5 |
scavenger receptor class B member 2 | ENSG00000138760 | SCARB2 | chr4:76158737-76213893:- | 8 | 15.5 |
bone morphogenetic protein receptor type 1B | ENSG00000138696 | BMPR1B | chr4:94757968-95158448:+ | 9 | 10.5 |
unc-5 netrin receptor C | ENSG00000182168 | UNC5C | chr4:95162504-95549206:- | 8 | 10.5 |
teneurin transmembrane protein 3 | ENSG00000218336 | TENM3 | chr4:182143987-182803024:+ | 9 | 14.5 |
semaphorin 5A | ENSG00000112902 | SEMA5A | chr5:9035026-9546075:- | 8 | 10.5 |
oncostatin M receptor | ENSG00000145623 | OSMR | chr5:38845858-38945596:+ | 9 | 11.5 |
family with sequence similarity 174 member A | ENSG00000174132 | FAM174A | chr5:100535305-100586741:+ | 8 | 10.5 |
glycoprotein integral membrane 1 | ENSG00000055211 | GINM1 | chr6:149566294-149591748:+ | 8 | 9.5 |
retinoic acid early transcript 1G | ENSG00000203722 | RAET1G | chr6:149916878-149923121:- | 9 | 11 |
claudin 3 | ENSG00000165215 | CLDN3 | chr7:73768997-73770270:- | 9 | 11.5 |
solute carrier family 26 member 3 | ENSG00000091138 | SLC26A3 | chr7:107765467-107803225:- | 9 | 10.5 |
contactin associated protein 2 | ENSG00000174469 | CNTNAP2 | chr7:146116002-148420998:+ | 8 | 9.5 |
solute carrier family 20 member 2 | ENSG00000168575 | SLC20A2 | chr8:42416475-42541926:- | 9 | 13.5 |
dendrocyte expressed seven transmembrane protein | ENSG00000164935 | DCSTAMP | chr8:104339087-104356689:+ | 8 | 9.5 |
protein tyrosine phosphatase receptor type D | ENSG00000153707 | PTPRD | chr9:8314246-10612723:- | 8 | 11.5 |
interleukin 3 receptor subunit alpha | ENSG00000185291 | IL3RA | chrX:1336616-1382689:+ | 9 | 12.5 |
solute carrier family 16 member 2 | ENSG00000147100 | SLC16A2 | chrX:74421461-74533917:+ | 8 | 10.5 |
claudin 2 | ENSG00000165376 | CLDN2 | chrX:106900164-106930861:+ | 9 | 10.5 |
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