GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
dipeptidase 1ENSG00000015413DPEP1chr16:89613308-89638456:+1314.5
thromboxane A2 receptorENSG00000006638TBXA2Rchr19:3594506-3606840:-1218
adrenoceptor beta 2ENSG00000169252ADRB2chr5:148825245-148828687:+1318
sphingosine-1-phosphate receptor 1ENSG00000170989S1PR1chr1:101236888-101241518:+1218
adenosine A1 receptorENSG00000163485ADORA1chr1:203090654-203167405:+1317
angiotensin II receptor type 1ENSG00000144891AGTR1chr3:148697784-148743008:+1317
integrin subunit beta 3ENSG00000259207ITGB3chr17:47253846-47311816:+1321.5
insulin receptorENSG00000171105INSRchr19:7112255-7294034:-1320.5
polycystin 2, transient receptor potential cation channelENSG00000118762PKD2chr4:88007668-88077777:+1218.5
adhesion G protein-coupled receptor G6ENSG00000112414ADGRG6chr6:142301854-142446266:+1315.5
toll like receptor 4ENSG00000136869TLR4chr9:117704332-117716871:+1316.5
EPH receptor A2ENSG00000142627EPHA2chr1:16124337-16156087:-1320.5
neurotrophic receptor tyrosine kinase 1ENSG00000198400NTRK1chr1:156815640-156881850:+1316.5
protein tyrosine phosphatase receptor type CENSG00000081237PTPRCchr1:198638671-198757283:+1218
MAS related GPR family member FENSG00000172935MRGPRFchr11:69004395-69013409:-1215
G protein-coupled receptor class C group 5 member AENSG00000013588GPRC5Achr12:12890782-12917937:+1318
thyroid stimulating hormone receptorENSG00000165409TSHRchr14:80954989-81146302:+1315
platelet and endothelial cell adhesion molecule 1ENSG00000261371PECAM1chr17:64319415-64413776:-1218.5
adhesion G protein-coupled receptor E5ENSG00000123146ADGRE5chr19:14380501-14408725:+1322
atypical chemokine receptor 3ENSG00000144476ACKR3chr2:236567787-236582358:+1317

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