GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
contactin associated protein 1 | ENSG00000108797 | CNTNAP1 | chr17:42682613-42699814:+ | 8 | 11.5 |
ATP binding cassette subfamily A member 8 | ENSG00000141338 | ABCA8 | chr17:68867292-68955392:- | 8 | 10.5 |
solute carrier family 16 member 3 | ENSG00000141526 | SLC16A3 | chr17:82228397-82261129:+ | 9 | 16.5 |
desmoglein 3 | ENSG00000134757 | DSG3 | chr18:31447795-31478702:+ | 9 | 10 |
interleukin 27 receptor subunit alpha | ENSG00000104998 | IL27RA | chr19:14031748-14053216:+ | 9 | 11.5 |
serine peptidase inhibitor, Kunitz type 2 | ENSG00000167642 | SPINT2 | chr19:38244035-38292614:+ | 8 | 12.5 |
leucine rich repeat and fibronectin type III domain containing 1 | ENSG00000128011 | LRFN1 | chr19:39306568-39315336:- | 8 | 11.5 |
fukutin related protein | ENSG00000181027 | FKRP | chr19:46746046-46776988:+ | 8 | 11.5 |
leucine rich repeat containing 4B | ENSG00000131409 | LRRC4B | chr19:50516892-50568045:- | 8 | 10.5 |
ADAM metallopeptidase domain 17 | ENSG00000151694 | ADAM17 | chr2:9488486-9555792:- | 8 | 15.5 |
interleukin 1 receptor like 2 | ENSG00000115598 | IL1RL2 | chr2:102186973-102240002:+ | 8 | 9.5 |
interleukin 18 receptor 1 | ENSG00000115604 | IL18R1 | chr2:102311529-102398775:+ | 8 | 11.5 |
activin A receptor type 2A | ENSG00000121989 | ACVR2A | chr2:147844517-147930826:+ | 9 | 11.5 |
lymphocyte antigen 75 | ENSG00000054219 | LY75 | chr2:159803355-159904749:- | 8 | 14.5 |
transient receptor potential cation channel subfamily M member 8 | ENSG00000144481 | TRPM8 | chr2:233917398-234019522:+ | 8 | 10.5 |
protein tyrosine phosphatase receptor type A | ENSG00000132670 | PTPRA | chr20:2864184-3039076:+ | 8 | 13.5 |
prostate transmembrane protein, androgen induced 1 | ENSG00000124225 | PMEPA1 | chr20:57648392-57711536:- | 8 | 10.5 |
pannexin 2 | ENSG00000073150 | PANX2 | chr22:50170731-50180294:+ | 9 | 10.5 |
interleukin 5 receptor subunit alpha | ENSG00000091181 | IL5RA | chr3:3066326-3126613:- | 9 | 11.5 |
receptor like tyrosine kinase | ENSG00000163785 | RYK | chr3:134065303-134250744:- | 9 | 11.5 |
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