GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
5-hydroxytryptamine receptor 1B | ENSG00000135312 | HTR1B | chr6:77462205-77463464:- | 9 | 14 |
cannabinoid receptor 2 | ENSG00000188822 | CNR2 | chr1:23870526-23913362:- | 8 | 13 |
amyloid beta precursor protein | ENSG00000142192 | APP | chr21:25880550-26171128:- | 8 | 18.5 |
lysophosphatidic acid receptor 3 | ENSG00000171517 | LPAR3 | chr1:84811602-84893213:- | 8 | 10 |
cholinergic receptor muscarinic 3 | ENSG00000133019 | CHRM3 | chr1:239386565-239915452:+ | 9 | 11 |
G protein-coupled receptor 158 | ENSG00000151025 | GPR158 | chr10:25175062-25602226:+ | 8 | 10 |
adrenoceptor alpha 2A | ENSG00000150594 | ADRA2A | chr10:111077163-111080907:+ | 9 | 13 |
leucine rich repeat containing G protein-coupled receptor 4 | ENSG00000205213 | LGR4 | chr11:27365961-27472775:- | 9 | 11 |
solute carrier family 2 member 3 | ENSG00000059804 | SLC2A3 | chr12:7919230-7936275:- | 8 | 17.5 |
complement C3a receptor 1 | ENSG00000171860 | C3AR1 | chr12:8058302-8066471:- | 8 | 10 |
hydroxycarboxylic acid receptor 3 | ENSG00000255398 | HCAR3 | chr12:122714756-122716892:- | 8 | 10 |
KISS1 receptor | ENSG00000116014 | KISS1R | chr19:917287-921015:+ | 9 | 11 |
G protein-coupled receptor 160 | ENSG00000173890 | GPR160 | chr3:170037929-170085403:+ | 8 | 10 |
dopamine receptor D5 | ENSG00000169676 | DRD5 | chr4:9781680-9784009:+ | 9 | 11 |
adhesion G protein-coupled receptor L3 | ENSG00000150471 | ADGRL3 | chr4:61201258-62078335:+ | 9 | 11 |
chloride voltage-gated channel 1 | ENSG00000188037 | CLCN1 | chr7:143316126-143352083:+ | 9 | 14.5 |
G protein-coupled receptor 157 | ENSG00000180758 | GPR157 | chr1:9100305-9129170:- | 8 | 11 |
colony stimulating factor 3 receptor | ENSG00000119535 | CSF3R | chr1:36466043-36483278:- | 9 | 11 |
semaphorin 6C | ENSG00000143434 | SEMA6C | chr1:151131685-151146664:- | 9 | 10.5 |
leucine rich repeat containing G protein-coupled receptor 6 | ENSG00000133067 | LGR6 | chr1:202193901-202319781:+ | 8 | 10 |
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