GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
natural cytotoxicity triggering receptor 3 | ENSG00000204475 | NCR3 | chr6:31588895-31592985:- | 9 | 10 |
peptidase inhibitor 16 | ENSG00000164530 | PI16 | chr6:36948263-36964837:+ | 9 | 12.5 |
transmembrane protein 63B | ENSG00000137216 | TMEM63B | chr6:44126914-44155519:+ | 10 | 14 |
solute carrier family 22 member 16 | ENSG00000004809 | SLC22A16 | chr6:110424687-110476641:- | 9 | 11.5 |
major facilitator superfamily domain containing 4B | ENSG00000173214 | KIAA1919 | chr6:111259348-111271167:+ | 9 | 11.5 |
LDL receptor related protein 11 | ENSG00000120256 | LRP11 | chr6:149818798-149864026:- | 9 | 10.5 |
solute carrier family 12 member 9 | ENSG00000146828 | SLC12A9 | chr7:100826820-100867009:+ | 9 | 14.5 |
solute carrier family 26 member 5 | ENSG00000170615 | SLC26A5 | chr7:103352730-103446177:- | 10 | 11.5 |
tetraspanin 33 | ENSG00000158457 | TSPAN33 | chr7:129144892-129169697:+ | 10 | 13.5 |
aquaporin 3 (Gill blood group) | ENSG00000165272 | AQP3 | chr9:33441154-33447611:- | 9 | 10.5 |
ciliary neurotrophic factor receptor | ENSG00000122756 | CNTFR | chr9:34551432-34590140:- | 10 | 11 |
solute carrier family 44 member 1 | ENSG00000070214 | SLC44A1 | chr9:105244622-105439171:+ | 9 | 17.5 |
sushi domain containing 1 | ENSG00000106868 | SUSD1 | chr9:112040785-112175408:- | 9 | 12.5 |
glycoprotein M6B | ENSG00000046653 | GPM6B | chrX:13771031-13938638:- | 10 | 12.5 |
plexin B3 | ENSG00000198753 | PLXNB3 | chrX:153764196-153779346:+ | 10 | 12 |
neuronal growth regulator 1 | ENSG00000172260 | NEGR1 | chr1:71395940-72282734:- | 9 | 16 |
leucine rich repeat containing 8 VRAC subunit C | ENSG00000171488 | LRRC8C | chr1:89633072-89769903:+ | 9 | 16.5 |
tetraspanin 8 | ENSG00000127324 | TSPAN8 | chr12:71125085-71441898:- | 10 | 14.5 |
ATPase H+ transporting V0 subunit a1 | ENSG00000033627 | ATP6V0A1 | chr17:42458844-42522611:+ | 10 | 15.5 |
mast cell expressed membrane protein 1 | ENSG00000183019 | MCEMP1 | chr19:7676628-7679826:+ | 9 | 13.5 |
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