GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
CD163 moleculeENSG00000177575CD163chr12:7470813-7503893:-1417.5
SLIT and NTRK like family member 6ENSG00000184564SLITRK6chr13:85792790-85799488:-1416.5
protein tyrosine phosphatase receptor type MENSG00000173482PTPRMchr18:7566782-8406861:+1318.5
leukocyte associated immunoglobulin like receptor 1ENSG00000167613LAIR1chr19:54351384-54370558:-1318.5
integrin subunit alpha 4ENSG00000115232ITGA4chr2:181457202-181536187:+1318.5
sushi domain containing 2ENSG00000099994SUSD2chr22:24181259-24189110:+1318.5
discoidin, CUB and LCCL domain containing 2ENSG00000057019DCBLD2chr3:98795941-98901689:-1318.5
integrin subunit beta 5ENSG00000082781ITGB5chr3:124761948-124901418:-1420.5
ATPase Na+/K+ transporting subunit beta 3ENSG00000069849ATP1B3chr3:141876124-141926514:+1422.5
neuroligin 1ENSG00000169760NLGN1chr3:173396284-174286644:+1416.5
interleukin 6 signal transducerENSG00000134352IL6STchr5:55935095-55994993:-1418.5
protocadherin gamma subfamily C, 3ENSG00000240184PCDHGC3chr5:141475947-141512979:+1418.5
ephrin B1ENSG00000090776EFNB1chrX:68828997-68842147:+1422.5
pannexin 1ENSG00000110218PANX1chr11:94128928-94181972:+1419.5
chondroitin sulfate proteoglycan 4ENSG00000173546CSPG4chr15:75674322-75712848:-1318.5
ATP binding cassette subfamily C member 1ENSG00000103222ABCC1chr16:15949577-16143074:+1319.5
stabilin 1ENSG00000010327STAB1chr3:52495338-52524495:+1315.5
roundabout guidance receptor 1ENSG00000169855ROBO1chr3:78597240-79767815:-1319
CD47 moleculeENSG00000196776CD47chr3:108043298-108091025:-1320.5
Thy-1 cell surface antigenENSG00000154096THY1chr11:119417378-119424985:-1319.5

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