GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
family with sequence similarity 171 member A2 | ENSG00000161682 | FAM171A2 | chr17:44353215-44363875:- | 9 | 12.5 |
tweety family member 2 | ENSG00000141540 | TTYH2 | chr17:74213514-74262020:+ | 10 | 11.5 |
multiple EGF like domains 8 | ENSG00000105429 | MEGF8 | chr19:42325609-42378769:+ | 9 | 12.5 |
CD37 molecule | ENSG00000104894 | CD37 | chr19:49335171-49343335:+ | 10 | 14.5 |
cyclin and CBS domain divalent metal cation transport mediator 3 | ENSG00000168763 | CNNM3 | chr2:96816245-96833911:+ | 9 | 15.5 |
ring finger protein 149 | ENSG00000163162 | RNF149 | chr2:101271219-101308701:- | 9 | 13.5 |
sodium voltage-gated channel alpha subunit 2 | ENSG00000136531 | SCN2A | chr2:165239402-165392310:+ | 10 | 11.5 |
ATP binding cassette subfamily B member 11 | ENSG00000073734 | ABCB11 | chr2:168922938-169031322:- | 9 | 10.5 |
leucine rich repeat neuronal 1 | ENSG00000175928 | LRRN1 | chr3:3799437-3847703:+ | 9 | 11.5 |
interleukin 17 receptor D | ENSG00000144730 | IL17RD | chr3:57089982-57170306:- | 9 | 10 |
solute carrier family 15 member 2 | ENSG00000163406 | SLC15A2 | chr3:121894089-121944102:+ | 10 | 11.5 |
ATP binding cassette subfamily C member 5 | ENSG00000114770 | ABCC5 | chr3:183919934-184018015:- | 9 | 12.5 |
fibroblast growth factor receptor like 1 | ENSG00000127418 | FGFRL1 | chr4:1009936-1026897:+ | 9 | 12.5 |
solute carrier family 2 member 9 | ENSG00000109667 | SLC2A9 | chr4:9771153-10054936:- | 9 | 13.5 |
gamma-aminobutyric acid type A receptor subunit alpha2 | ENSG00000151834 | GABRA2 | chr4:46248427-46475230:- | 10 | 11.5 |
ephrin A5 | ENSG00000184349 | EFNA5 | chr5:107376889-107670895:- | 10 | 11.5 |
thioredoxin domain containing 15 | ENSG00000113621 | TXNDC15 | chr5:134873803-134901525:+ | 9 | 11.5 |
solute carrier family 26 member 2 | ENSG00000155850 | SLC26A2 | chr5:149960737-149993455:+ | 10 | 14.5 |
ADAM metallopeptidase domain 19 | ENSG00000135074 | ADAM19 | chr5:157395534-157575775:- | 9 | 12.5 |
MHC class I polypeptide-related sequence B | ENSG00000204516 | MICB | chr6:31494881-31511124:+ | 10 | 13 |
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